Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KLF3
  • Mouse genes Klf3
  • Rat genes Klf3
  • Zfish genes klf3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Klf3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	klf3	IDA		Zfish	PMID:26015096
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	klf3	IDA		Zfish	PMID:26015096
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:Q13363-2	Human	PMID:24722188
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:A2ABF9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:Q12933	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:Q13643	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:Q68G74	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:Q92997	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:Q13363-2	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:Q13643	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:P32243-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:P56545-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:Q12933	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:Q13643	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:Q96KQ7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:Q9UPM6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:O14901	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:O14908-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:O43464	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:O43933	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:O60333-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:P01112	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:P02489	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:P04792	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:P22607	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:P28799	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:P46379-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:P54253	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:P60891	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:Q5T3J3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:Q86V38	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:Q92876	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:Q9BVL2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:Q9NX09	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:Q9Y2W7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:Q9Y5Z0	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:P28799	Human	PMID:35140242
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:P54253	Human	PMID:35140242
Molecular Function	GO:0005515	protein binding	KLF3	IPI	UniProtKB:Q96KQ7	Human	PMID:35140242
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Klf3	IDA		Mouse	MGI:MGI:5302142|PMID:22115574
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	KLF3	IDA		Human	PMID:28473536
Cellular Component	GO:0005654	nucleoplasm	KLF3	IDA		Human	GO_REF:0000052
Biological Process	GO:1901653	cellular response to peptide	Klf3	IEP		Rat	PMID:18406357|RGD:2316543
Biological Process	GO:0043249	erythrocyte maturation	klf3	IMP	ZFIN:ZDB-MRPHLNO-150903-3	Zfish	PMID:26015096
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Klf3	IMP		Mouse	MGI:MGI:3820836|PMID:18687676
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	klf3	IDA		Zfish	PMID:26015096|ZFIN:ZDB-PUB-150528-4

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern