Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Klhl41

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes KLHL41
- Mouse genes Klhl41
- Rat genes Klhl41
- Zfish genes klhl41a,klhl41b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Klhl41

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	KLHL41	IPI	UniProtKB:P20929	Human	PMID:23414517
Molecular Function	GO:0005515	protein binding	KLHL41	IPI	UniProtKB:P20929-4	Human	PMID:23414517
Molecular Function	GO:0005515	protein binding	KLHL41	IPI	UniProtKB:Q96PM5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KLHL41	IPI	UniProtKB:Q96LM5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLHL41	IPI	UniProtKB:Q96PM5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLHL41	IPI	UniProtKB:P40337-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Klhl41	IPI	UniProtKB:Q80XB4	Rat	PMID:12692149\|RGD:8554833
Cellular Component	GO:0031463	Cul3-RING ubiquitin ligase complex	KLHL41	IDA		Human	PMID:15983046
Cellular Component	GO:0005737	cytoplasm	KLHL41	IDA		Human	PMID:19424503
Cellular Component	GO:0005737	cytoplasm	Klhl41	IDA		Mouse	MGI:MGI:5424274\|PMID:22562206
Cellular Component	GO:0005737	cytoplasm	Klhl41	IDA		Mouse	MGI:MGI:5487520\|PMID:21368295
Cellular Component	GO:0005737	cytoplasm	Klhl41	IDA		Mouse	MGI:MGI:5486546\|PMID:18178185
Cellular Component	GO:0005737	cytoplasm	Klhl41	IDA		Rat	PMID:10713668\|RGD:634002
Cellular Component	GO:0005856	cytoskeleton	Klhl41	IDA		Mouse	MGI:MGI:5486546\|PMID:18178185
Cellular Component	GO:0005829	cytosol	KLHL41	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005789	endoplasmic reticulum membrane	KLHL41	IDA		Human	PMID:24268659
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Klhl41	IDA		Mouse	MGI:MGI:5586786\|PMID:24268659
Cellular Component	GO:0031430	M band	Klhl41	IDA		Mouse	PMID:22562206
Cellular Component	GO:0005654	nucleoplasm	KLHL41	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	KLHL41	IDA		Human	GO_REF:0000052
Cellular Component	GO:0031143	pseudopodium	Klhl41	IDA		Rat	PMID:10713668\|RGD:634002
Cellular Component	GO:0033017	sarcoplasmic reticulum membrane	KLHL41	IDA		Human	PMID:24268659
Cellular Component	GO:0033017	sarcoplasmic reticulum membrane	Klhl41	IDA		Mouse	MGI:MGI:5586786\|PMID:24268659
Biological Process	GO:0030239	myofibril assembly	Klhl41	IMP		Mouse	MGI:MGI:5486546\|PMID:18178185
Biological Process	GO:0016567	protein ubiquitination	KLHL41	IDA		Human	PMID:15983046
Biological Process	GO:0031269	pseudopodium assembly	Klhl41	IMP		Rat	PMID:10713668\|RGD:634002
Biological Process	GO:0045661	regulation of myoblast differentiation	Klhl41	IMP		Mouse	MGI:MGI:5487520\|PMID:21368295
Biological Process	GO:2000291	regulation of myoblast proliferation	Klhl41	IMP		Mouse	MGI:MGI:5487520\|PMID:21368295
Biological Process	GO:0060297	regulation of sarcomere organization	klhl41b	IGI	ZFIN:ZDB-MRPHLNO-210623-1,ZFIN:ZDB-MRPHLNO-140213-5,ZFIN:ZDB-MRPHLNO-140213-7	Zfish	PMID:30986853
Biological Process	GO:0060297	regulation of sarcomere organization	klhl41a	IGI	ZFIN:ZDB-MRPHLNO-140213-5,ZFIN:ZDB-MRPHLNO-140213-7	Zfish	PMID:30986853
Biological Process	GO:0060297	regulation of sarcomere organization	klhl41a	IGI	ZFIN:ZDB-MRPHLNO-210623-1,ZFIN:ZDB-MRPHLNO-140213-5,ZFIN:ZDB-MRPHLNO-140213-7	Zfish	PMID:30986853
Biological Process	GO:0060297	regulation of sarcomere organization	klhl41b	IGI	ZFIN:ZDB-MRPHLNO-140213-5,ZFIN:ZDB-MRPHLNO-140213-7	Zfish	PMID:30986853
Biological Process	GO:2001014	regulation of skeletal muscle cell differentiation	Klhl41	IMP		Mouse	PMID:22562206
Biological Process	GO:0045214	sarcomere organization	klhl41b	IGI	ZFIN:ZDB-MRPHLNO-140213-5,ZFIN:ZDB-MRPHLNO-140213-7	Zfish	PMID:24268659
Biological Process	GO:0045214	sarcomere organization	klhl41b	IMP	ZFIN:ZDB-MRPHLNO-140213-7	Zfish	PMID:24268659
Biological Process	GO:0045214	sarcomere organization	klhl41a	IMP	ZFIN:ZDB-MRPHLNO-140213-5	Zfish	PMID:24268659
Biological Process	GO:0045214	sarcomere organization	klhl41a	IGI	ZFIN:ZDB-MRPHLNO-140213-5,ZFIN:ZDB-MRPHLNO-140213-7	Zfish	PMID:24268659
Biological Process	GO:0035914	skeletal muscle cell differentiation	Klhl41	IDA		Mouse	MGI:MGI:5424274\|PMID:22562206
Biological Process	GO:0048741	skeletal muscle fiber development	klhl41b	IGI	ZFIN:ZDB-MRPHLNO-140213-5,ZFIN:ZDB-MRPHLNO-140213-7	Zfish	PMID:24268659
Biological Process	GO:0048741	skeletal muscle fiber development	klhl41b	IMP	ZFIN:ZDB-MRPHLNO-140213-7	Zfish	PMID:24268659
Biological Process	GO:0048741	skeletal muscle fiber development	klhl41a	IMP	ZFIN:ZDB-MRPHLNO-140213-5	Zfish	PMID:24268659
Biological Process	GO:0048741	skeletal muscle fiber development	klhl41a	IGI	ZFIN:ZDB-MRPHLNO-140213-5,ZFIN:ZDB-MRPHLNO-140213-7	Zfish	PMID:24268659
Biological Process	GO:0036269	swimming behavior	klhl41a	IGI	ZFIN:ZDB-MRPHLNO-140213-5,ZFIN:ZDB-MRPHLNO-140213-7	Zfish	PMID:30986853
Biological Process	GO:0036269	swimming behavior	klhl41a	IGI	ZFIN:ZDB-MRPHLNO-210623-1,ZFIN:ZDB-MRPHLNO-140213-5,ZFIN:ZDB-MRPHLNO-140213-7	Zfish	PMID:30986853
Biological Process	GO:0036269	swimming behavior	klhl41b	IGI	ZFIN:ZDB-MRPHLNO-210623-1,ZFIN:ZDB-MRPHLNO-140213-5,ZFIN:ZDB-MRPHLNO-140213-7	Zfish	PMID:30986853
Biological Process	GO:0036269	swimming behavior	klhl41b	IGI	ZFIN:ZDB-MRPHLNO-140213-5,ZFIN:ZDB-MRPHLNO-140213-7	Zfish	PMID:30986853

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.