Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KLHL42
  • Mouse genes Klhl42
  • Rat genes Klhl42
  • Zfish genes klhl42
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Klhl42

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:Q9UHV2	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:Q9UMX0	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:O75449	Human	PMID:19261606
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:Q13618	Human	PMID:19261606
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:O75886	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:P36406	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:Q08AL9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:Q13137	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:Q8WTU0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:Q92567	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:Q9UMX0-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:Q9Y2D8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:O43482	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:O75886	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:P01189	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:P07237	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:P15173	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:P17540	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:P36406	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:Q04864-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:Q0VD86	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:Q15038	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:Q3LI73	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:Q5W5X9-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:Q7Z3H0-1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:Q8N1B4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:Q8WTU0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:Q8WUE5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:Q96D30	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:Q99471	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:Q9BXL8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:Q9BYV2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:Q9UHD9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:Q9UHV2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:Q9UJW9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLHL42	IPI	UniProtKB:Q9UMX0	Human	PMID:32296183
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	KLHL42	IDA		Human	PMID:19261606
Cellular Component	GO:0031463	Cul3-RING ubiquitin ligase complex	KLHL42	IDA		Human	PMID:19261606
Biological Process	GO:0031018	endocrine pancreas development	klhl42	IMP	ZFIN:ZDB-MRPHLNO-160621-45	Zfish	PMID:26963759
Biological Process	GO:0042593	glucose homeostasis	klhl42	IMP	ZFIN:ZDB-MRPHLNO-160621-45	Zfish	PMID:26963759
Biological Process	GO:1990798	pancreas regeneration	klhl42	IMP	ZFIN:ZDB-MRPHLNO-160621-45	Zfish	PMID:26963759
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	KLHL42	IDA		Human	PMID:19261606
Biological Process	GO:0000209	protein polyubiquitination	KLHL42	IDA		Human	PMID:19261606
Biological Process	GO:0032886	regulation of microtubule-based process	KLHL42	IMP		Human	PMID:19261606

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern