Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KLK4
  • Mouse genes Klk4
  • Rat genes Klk4
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Klk4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	KLK4	IPI	UniProtKB:Q06418	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KLK4	IPI	UniProtKB:P20155	Human	PMID:31391482
Biological Process	GO:0097186	amelogenesis	KLK4	IMP		Human	PMID:15235027
Biological Process	GO:0097186	amelogenesis	Klk4	IMP	MGI:MGI:4355346	Mouse	PMID:19578120
Biological Process	GO:0097186	amelogenesis	Klk4	IMP	MGI:MGI:4355346	Mouse	PMID:22243248
Biological Process	GO:0097186	amelogenesis	Klk4	IMP	MGI:MGI:4355346	Mouse	PMID:21454549
Biological Process	GO:0022617	extracellular matrix disassembly	Klk4	IMP	MGI:MGI:4355346	Mouse	PMID:22243248
Biological Process	GO:0030163	protein catabolic process	Klk4	IMP	MGI:MGI:4355346	Mouse	PMID:22243248

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern