Comparative GO Graph (mouse, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes
  • Mouse genes Klre1
  • Rat genes Klre1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Klre1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	Klre1	IPI	PR:Q8CJC7	Mouse	PMID:14707119
Molecular Function	GO:0042802	identical protein binding	Klre1	IPI	RGD:727903	Rat	PMID:12782717|RGD:1299590
Molecular Function	GO:0019903	protein phosphatase binding	Klre1	IPI	RGD:620660	Rat	PMID:12782717|RGD:1299590
Molecular Function	GO:0004888	transmembrane signaling receptor activity	Klre1	IDA		Mouse	PMID:14707119
Cellular Component	GO:0009986	cell surface	Klre1	IDA		Rat	PMID:12782717|RGD:1299590
Cellular Component	GO:0009897	external side of plasma membrane	Klre1	IDA		Mouse	PMID:14707119
Cellular Component	GO:0005886	plasma membrane	Klre1	IDA		Mouse	PMID:14707119
Biological Process	GO:0030101	natural killer cell activation	Klre1	IDA		Mouse	PMID:14707119
Biological Process	GO:0002859	negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	Klre1	IDA		Rat	PMID:12782717|RGD:1299590
Biological Process	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	Klre1	IMP		Mouse	PMID:14707119
Biological Process	GO:0032729	positive regulation of type II interferon production	Klre1	IDA		Mouse	PMID:14707119
Biological Process	GO:0002223	stimulatory C-type lectin receptor signaling pathway	Klre1	IDA		Mouse	PMID:14707119
Biological Process	GO:0032609	type II interferon production	Klre1	IDA		Mouse	PMID:14707119

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern