Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KMO
  • Mouse genes Kmo
  • Rat genes Kmo
  • Zfish genes kmo
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kmo

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0071949	FAD binding	KMO	IDA		Human	PMID:29429898
Molecular Function	GO:0050660	flavin adenine dinucleotide binding	KMO	IDA		Human	PMID:10672018
Molecular Function	GO:0004502	kynurenine 3-monooxygenase activity	KMO	IDA		Human	PMID:10672018
Molecular Function	GO:0004502	kynurenine 3-monooxygenase activity	KMO	IDA		Human	PMID:23575632
Molecular Function	GO:0004502	kynurenine 3-monooxygenase activity	KMO	IDA		Human	PMID:26752518
Molecular Function	GO:0004502	kynurenine 3-monooxygenase activity	KMO	IDA		Human	PMID:29208702
Molecular Function	GO:0004502	kynurenine 3-monooxygenase activity	KMO	IDA		Human	PMID:29429898
Molecular Function	GO:0004502	kynurenine 3-monooxygenase activity	KMO	IDA		Human	PMID:9237672
Molecular Function	GO:0004502	kynurenine 3-monooxygenase activity	Kmo	IMP		Mouse	MGI:MGI:5780894|PMID:26752518
Molecular Function	GO:0004502	kynurenine 3-monooxygenase activity	Kmo	IDA		Rat	PMID:1332540|RGD:8554522
Molecular Function	GO:0004502	kynurenine 3-monooxygenase activity	Kmo	IDA		Rat	PMID:26752518|RGD:11342439
Molecular Function	GO:0004502	kynurenine 3-monooxygenase activity	Kmo	IDA		Rat	PMID:3400092|RGD:2290313
Molecular Function	GO:0004502	kynurenine 3-monooxygenase activity	Kmo	IDA		Rat	PMID:6259288|RGD:2290309
Molecular Function	GO:0004502	kynurenine 3-monooxygenase activity	Kmo	IDA		Rat	PMID:7131097|RGD:2290310
Molecular Function	GO:0016174	NAD(P)H oxidase H2O2-forming activity	KMO	IDA		Human	PMID:10672018
Molecular Function	GO:0016174	NAD(P)H oxidase H2O2-forming activity	KMO	IDA		Human	PMID:23575632
Molecular Function	GO:0016174	NAD(P)H oxidase H2O2-forming activity	KMO	IDA		Human	PMID:29429898
Cellular Component	GO:0005615	extracellular space	Kmo	IDA		Rat	PMID:29217494|RGD:13703051
Cellular Component	GO:0005743	mitochondrial inner membrane	Kmo	HDA		Mouse	PMID:12865426
Cellular Component	GO:0005741	mitochondrial outer membrane	Kmo	IDA		Rat	PMID:10672018|RGD:8554335
Cellular Component	GO:0005741	mitochondrial outer membrane	Kmo	IDA		Rat	PMID:1332540|RGD:8554522
Cellular Component	GO:0005741	mitochondrial outer membrane	Kmo	IDA		Rat	PMID:7131097|RGD:2290310
Cellular Component	GO:0005739	mitochondrion	Kmo	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Kmo	IDA		Rat	PMID:3346732|RGD:2290308
Cellular Component	GO:0005739	mitochondrion	Kmo	IDA		Rat	PMID:6466295|RGD:2290312
Biological Process	GO:0007568	aging	Kmo	IEP		Rat	PMID:15970278|RGD:13703059
Biological Process	GO:0071347	cellular response to interleukin-1	Kmo	IEP		Rat	PMID:25675848|RGD:13513907
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Kmo	IEP		Rat	PMID:26524415|RGD:13703043
Biological Process	GO:0034276	kynurenic acid biosynthetic process	Kmo	IMP		Rat	PMID:15829251|RGD:13513901
Biological Process	GO:0070189	kynurenine metabolic process	KMO	IDA		Human	PMID:10672018
Biological Process	GO:0070189	kynurenine metabolic process	KMO	IDA		Human	PMID:26752518
Biological Process	GO:0070189	kynurenine metabolic process	KMO	IDA		Human	PMID:29208702
Biological Process	GO:0070189	kynurenine metabolic process	KMO	IDA		Human	PMID:29429898
Biological Process	GO:0070189	kynurenine metabolic process	Kmo	IMP		Mouse	MGI:MGI:5780894|PMID:26752518
Biological Process	GO:0070189	kynurenine metabolic process	Kmo	IDA		Rat	PMID:26752518|RGD:11342439
Biological Process	GO:0097052	L-kynurenine metabolic process	Kmo	IDA		Rat	PMID:23690293|RGD:13513904
Biological Process	GO:0019674	NAD metabolic process	KMO	IDA		Human	PMID:23575632
Biological Process	GO:0019674	NAD metabolic process	KMO	IDA		Human	PMID:29429898
Biological Process	GO:0019674	NAD metabolic process	Kmo	IDA		Rat	PMID:1332540|RGD:8554522
Biological Process	GO:0072015	podocyte development	kmo	IMP	ZFIN:ZDB-MRPHLNO-170113-1	Zfish	PMID:27020856
Biological Process	GO:0072015	podocyte development	kmo	IMP	ZFIN:ZDB-MRPHLNO-170113-2	Zfish	PMID:27020856
Biological Process	GO:0014049	positive regulation of glutamate secretion	Kmo	IMP		Rat	PMID:15829251|RGD:13513901
Biological Process	GO:1903296	positive regulation of glutamate secretion, neurotransmission	Kmo	IMP		Rat	PMID:15829251|RGD:13513901
Biological Process	GO:1901216	positive regulation of neuron death	Kmo	IMP		Rat	PMID:12354294|RGD:13513903
Biological Process	GO:0032496	response to lipopolysaccharide	Kmo	IEP		Rat	PMID:18584961|RGD:13513902
Biological Process	GO:0009651	response to salt stress	KMO	IDA		Human	PMID:10672018
Biological Process	GO:0001878	response to yeast	kmo	IDA		Zfish	PMID:23947337

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern