Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KMT5B
  • Mouse genes Kmt5b
  • Rat genes Kmt5b
  • Zfish genes kmt5b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kmt5b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	KMT5B	IDA		Human	PMID:28114273
Molecular Function	GO:0042799	histone H4K20 methyltransferase activity	KMT5B	IDA		Human	PMID:24396869
Molecular Function	GO:0042799	histone H4K20 methyltransferase activity	KMT5B	IMP		Human	PMID:28114273
Molecular Function	GO:0042799	histone H4K20 methyltransferase activity	Kmt5b	IDA		Mouse	MGI:MGI:5575440|PMID:24049080
Molecular Function	GO:0042799	histone H4K20 methyltransferase activity	Kmt5b	IDA		Mouse	PMID:15145825
Molecular Function	GO:0042054	histone methyltransferase activity	KMT5B	IDA		Human	PMID:17707234
Molecular Function	GO:0005515	protein binding	KMT5B	IPI	UniProtKB:Q9H2G4	Human	PMID:32296183
Molecular Function	GO:1904047	S-adenosyl-L-methionine binding	Kmt5b	IDA		Mouse	MGI:MGI:5575440|PMID:24049080
Cellular Component	GO:0000779	condensed chromosome, centromeric region	Kmt5b	IDA		Mouse	PMID:15145825
Cellular Component	GO:0005654	nucleoplasm	KMT5B	IDA		Human	GO_REF:0000052
Biological Process	GO:0006281	DNA repair	KMT5B	IMP		Human	PMID:28114273
Biological Process	GO:0034770	histone H4-K20 methylation	kmt5b	IGI	ZFIN:ZDB-MRPHLNO-120424-3,ZFIN:ZDB-MRPHLNO-120424-4	Zfish	PMID:22398447
Biological Process	GO:0016570	histone modification	Kmt5b	IDA		Mouse	MGI:MGI:3043964|PMID:15145825
Biological Process	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining	KMT5B	IMP		Human	PMID:28114273
Biological Process	GO:0045830	positive regulation of isotype switching	Kmt5b	IMP		Mouse	MGI:MGI:6370097|PMID:28114273
Biological Process	GO:0040014	regulation of multicellular organism growth	kmt5b	IGI	ZFIN:ZDB-MRPHLNO-120424-3,ZFIN:ZDB-MRPHLNO-120424-4	Zfish	PMID:22398447

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern