Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KNTC1
  • Mouse genes Kntc1
  • Rat genes Kntc1
  • Zfish genes kntc1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kntc1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	KNTC1	IPI	UniProtKB:O43264	Human	PMID:11146660
Molecular Function	GO:0005515	protein binding	KNTC1	IPI	UniProtKB:Q9H900	Human	PMID:12686595
Molecular Function	GO:0005515	protein binding	KNTC1	IPI	UniProtKB:Q96EA4	Human	PMID:19468067
Molecular Function	GO:0005515	protein binding	KNTC1	IPI	UniProtKB:Q9H900	Human	PMID:20462495
Cellular Component	GO:0015629	actin cytoskeleton	KNTC1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	KNTC1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005828	kinetochore microtubule	KNTC1	IDA		Human	PMID:11146660
Cellular Component	GO:0005886	plasma membrane	KNTC1	IDA		Human	GO_REF:0000052
Cellular Component	GO:1990423	RZZ complex	KNTC1	IPI		Human	PMID:25849506
Cellular Component	GO:1990423	RZZ complex	KNTC1	IDA		Human	PMID:20462495
Cellular Component	GO:0000922	spindle pole	KNTC1	IDA		Human	PMID:11146660
Biological Process	GO:0007094	mitotic spindle assembly checkpoint signaling	KNTC1	IDA		Human	PMID:11146660

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern