Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KPNA2
  • Mouse genes Kpna2
  • Rat genes Kpna2,LOC100359600
  • Zfish genes kpna2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kpna2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0140297	DNA-binding transcription factor binding	Kpna2	IPI	UniProtKB:P06400	Mouse	MGI:MGI:5882908|PMID:12695505
Molecular Function	GO:0042826	histone deacetylase binding	KPNA2	IPI	UniProtKB:P56524	Human	PMID:10869435
Molecular Function	GO:0061608	nuclear import signal receptor activity	KPNA2	IDA		Human	PMID:32290222
Molecular Function	GO:0061608	nuclear import signal receptor activity	Kpna2	IDA		Mouse	PMID:15719015
Molecular Function	GO:0061608	nuclear import signal receptor activity	Kpna2	IDA		Mouse	PMID:15689618
Molecular Function	GO:0008139	nuclear localization sequence binding	KPNA2	IDA		Human	PMID:17324944
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q14974-1	Human	PMID:10353244
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q14974	Human	PMID:10523667
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:P40617	Human	PMID:10980193
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q14974	Human	PMID:11024021
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:P03101	Human	PMID:11971900
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:P03101	Human	PMID:12551970
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:P03126	Human	PMID:12551970
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:P03101	Human	PMID:15507604
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:P03107	Human	PMID:15507604
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q5VWG9	Human	PMID:15870280
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q7Z7C8	Human	PMID:15870280
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:P27695	Human	PMID:15942031
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:P52926	Human	PMID:17324944
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:A0A3G5BIZ0	Human	PMID:17596301
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q14974	Human	PMID:17596301
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q14974-1	Human	PMID:19668212
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:O94992	Human	PMID:19883659
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:O94992|UniProtKB:Q96MH2	Human	PMID:19883659
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q9UH99	Human	PMID:20551905
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:P03070	Human	PMID:20701745
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q14974	Human	PMID:20701745
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:P06703	Human	PMID:20965181
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:P29034	Human	PMID:20965181
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q6GQG6	Human	PMID:20965181
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q8WYA6	Human	PMID:21385873
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:P05412	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:P07910	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:P03126	Human	PMID:22898364
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:P19712:PRO_0000038050	Human	PMID:24965446
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:O75478	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:P07910	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:P37198	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:P40692	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:P63010	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q53SE7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q6A162	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q7Z6G3-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q86Y26	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q8IX15-3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q8N6Y0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q8NBZ0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q93062	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q96PV4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q99750	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q9BRK4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q9BYV2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q9HAN9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q9NP66	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q9UJW9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q9UKX7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q9Y5V3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:P0DOE7	Human	PMID:25556234
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:P05412	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q15637	Human	PMID:26420826
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q14974	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q14974	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:P46379	Human	PMID:29042515
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:K9N643	Human	PMID:29370303
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:P40692	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:P40692	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q9HAN9	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q9UJW9	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q9Y5V3	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:O43148	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:P40692	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q96C86	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q9HAN9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q9UBU8-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q9UKX7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q16236	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:P0DTC6	Human	PMID:32979938
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:K9N643	Human	PMID:33060197
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:P0DTC6	Human	PMID:33097660
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q14653	Human	PMID:34950606
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q14974	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:P03070	Human	PMID:9168958
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:P46063	Human	PMID:9168958
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:P04620	Human	PMID:9405152
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:Q14974	Human	PMID:9405152
Molecular Function	GO:0005515	protein binding	KPNA2	IPI	UniProtKB:P38398	Human	PMID:9497340
Molecular Function	GO:0005515	protein binding	Kpna2	IPI	UniProtKB:Q9BYF1	Mouse	MGI:MGI:6827201|PMID:34031383
Molecular Function	GO:0005515	protein binding	Kpna2	IPI	UniProtKB:Q15637	Mouse	MGI:MGI:5700260|PMID:26420826
Molecular Function	GO:0005515	protein binding	Kpna2	IPI	UniProtKB:P31345	Mouse	MGI:MGI:5919323|PMID:25599645
Molecular Function	GO:0005515	protein binding	Kpna2	IPI	UniProtKB:P06180	Mouse	MGI:MGI:5882908|PMID:12695505
Molecular Function	GO:0005515	protein binding	Kpna2	IPI	UniProtKB:Q7TPV4	Mouse	MGI:MGI:3688337|PMID:12941609
Molecular Function	GO:0005515	protein binding	Kpna2	IPI	UniProtKB:B4LTG5	Mouse	MGI:MGI:5693713|PMID:25283549
Molecular Function	GO:0005515	protein binding	Kpna2	IPI	UniProtKB:P03070	Mouse	MGI:MGI:5693237|PMID:10764582
Molecular Function	GO:0005515	protein binding	Kpna2	IPI	UniProtKB:Q8BUE4	Mouse	MGI:MGI:6378077|PMID:26689472
Molecular Function	GO:0005515	protein binding	Kpna2	IPI	UniProtKB:P01580|UniProtKB:P03070	Mouse	MGI:MGI:3795810|PMID:18405666
Molecular Function	GO:0005515	protein binding	Kpna2	IPI	UniProtKB:P29034|UniProtKB:Q3SYU7	Mouse	MGI:MGI:5693364|PMID:20965181
Molecular Function	GO:0005515	protein binding	Kpna2	IPI	PR:P15919	Mouse	PMID:19324890
Molecular Function	GO:0005515	protein binding	Kpna2	IPI	PR:P70168	Mouse	PMID:20699224
Molecular Function	GO:0003723	RNA binding	KPNA2	HDA		Human	PMID:22681889
Cellular Component	GO:0010494	cytoplasmic stress granule	Kpna2	IDA		Mouse	MGI:MGI:6148443|PMID:27430620
Cellular Component	GO:0005829	cytosol	KPNA2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0098978	glutamatergic synapse	Kpna2	IDA		Mouse	PMID:15603742
Cellular Component	GO:0098978	glutamatergic synapse	Kpna2	IMP		Mouse	PMID:15603742
Cellular Component	GO:0016020	membrane	KPNA2	HDA		Human	PMID:19946888
Cellular Component	GO:0042564	NLS-dependent protein nuclear import complex	KPNA2	IPI		Human	PMID:10353244
Cellular Component	GO:0031965	nuclear membrane	KPNA2	IDA		Human	PMID:7635189
Cellular Component	GO:0005654	nucleoplasm	KPNA2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0014069	postsynaptic density	Kpna2	IEP		Mouse	PMID:15603742
Cellular Component	GO:0014069	postsynaptic density	Kpna2	IDA		Mouse	PMID:15603742
Biological Process	GO:0075506	entry of viral genome into host nucleus through nuclear pore complex via importin	KPNA2	IMP		Human	PMID:28189564
Biological Process	GO:0075506	entry of viral genome into host nucleus through nuclear pore complex via importin	Kpna2	IMP		Mouse	PMID:28189564
Biological Process	GO:0006607	NLS-bearing protein import into nucleus	KPNA2	IDA		Human	PMID:17324944
Biological Process	GO:1903902	positive regulation of viral life cycle	KPNA2	IMP		Human	PMID:28189564
Biological Process	GO:1903902	positive regulation of viral life cycle	Kpna2	IMP		Mouse	PMID:28189564
Biological Process	GO:0099527	postsynapse to nucleus signaling pathway	Kpna2	IDA		Mouse	PMID:15603742
Biological Process	GO:0099527	postsynapse to nucleus signaling pathway	Kpna2	IMP		Mouse	PMID:15603742
Biological Process	GO:0006606	protein import into nucleus	KPNA2	IDA		Human	PMID:32290222
Biological Process	GO:0006606	protein import into nucleus	Kpna2	IDA		Mouse	PMID:15689618
Biological Process	GO:0006606	protein import into nucleus	Kpna2	IDA		Mouse	PMID:15719015
Biological Process	GO:0046015	regulation of transcription by glucose	Kpna2	IDA		Rat	PMID:11988093|RGD:633087

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern