Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KPNA6
  • Mouse genes Kpna6
  • Rat genes Kpna6
  • Zfish genes kpna6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kpna6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0061608	nuclear import signal receptor activity	Kpna6	IDA		Mouse	PMID:15689618
Molecular Function	GO:0005515	protein binding	KPNA6	IPI	UniProtKB:Q14974	Human	PMID:10523667
Molecular Function	GO:0005515	protein binding	KPNA6	IPI	UniProtKB:Q16594	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	KPNA6	IPI	UniProtKB:P03466	Human	PMID:20064372
Molecular Function	GO:0005515	protein binding	KPNA6	IPI	UniProtKB:Q05322	Human	PMID:22810585
Molecular Function	GO:0005515	protein binding	KPNA6	IPI	UniProtKB:Q05322	Human	PMID:25158218
Molecular Function	GO:0005515	protein binding	KPNA6	IPI	UniProtKB:P46087	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KPNA6	IPI	UniProtKB:Q9UKX7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KPNA6	IPI	UniProtKB:P31345	Human	PMID:25599645
Molecular Function	GO:0005515	protein binding	KPNA6	IPI	UniProtKB:P01583	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	KPNA6	IPI	UniProtKB:Q15637	Human	PMID:26420826
Molecular Function	GO:0005515	protein binding	KPNA6	IPI	UniProtKB:Q14974	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	KPNA6	IPI	UniProtKB:P03466	Human	PMID:28169297
Molecular Function	GO:0005515	protein binding	KPNA6	IPI	UniProtKB:O14893	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KPNA6	IPI	UniProtKB:O43148	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KPNA6	IPI	UniProtKB:O75564-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KPNA6	IPI	UniProtKB:P20700	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KPNA6	IPI	UniProtKB:P78424	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KPNA6	IPI	UniProtKB:Q16594	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KPNA6	IPI	UniProtKB:Q86YD7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KPNA6	IPI	UniProtKB:Q92688	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KPNA6	IPI	UniProtKB:Q92993	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KPNA6	IPI	UniProtKB:Q96C86	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KPNA6	IPI	UniProtKB:Q96HA1-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KPNA6	IPI	UniProtKB:Q9BUI4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KPNA6	IPI	UniProtKB:Q9HAN9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KPNA6	IPI	UniProtKB:Q9UKX7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KPNA6	IPI	UniProtKB:Q9Y5V3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KPNA6	IPI	UniProtKB:X5D778	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KPNA6	IPI	UniProtKB:Q14653	Human	PMID:34950606
Molecular Function	GO:0005515	protein binding	Kpna6	IPI	UniProtKB:O60481	Mouse	MGI:MGI:4943378|PMID:18716025
Molecular Function	GO:0005515	protein binding	Kpna6	IPI	PR:Q9R194	Mouse	PMID:15689618
Cellular Component	GO:0016020	membrane	KPNA6	HDA		Human	PMID:19946888
Cellular Component	GO:0042564	NLS-dependent protein nuclear import complex	KPNA6	IPI		Human	PMID:10523667
Biological Process	GO:0075506	entry of viral genome into host nucleus through nuclear pore complex via importin	KPNA6	IMP		Human	PMID:28189564
Biological Process	GO:0075506	entry of viral genome into host nucleus through nuclear pore complex via importin	Kpna6	IMP	MGI:MGI:3856636	Mouse	PMID:28189564
Biological Process	GO:0060135	maternal process involved in female pregnancy	Kpna6	IMP	MGI:MGI:3856636	Mouse	PMID:21479251
Biological Process	GO:0060135	maternal process involved in female pregnancy	Kpna6	IMP	MGI:MGI:5004867	Mouse	PMID:21479251
Biological Process	GO:0030682	mitigation of host defenses by symbiont	Kpna6	IMP	MGI:MGI:3856636	Mouse	PMID:28189564
Biological Process	GO:1900017	positive regulation of cytokine production involved in inflammatory response	Kpna6	IMP	MGI:MGI:3856636	Mouse	PMID:28189564
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Kpna6	IMP	MGI:MGI:3856636	Mouse	PMID:21479251
Biological Process	GO:1903902	positive regulation of viral life cycle	KPNA6	IMP		Human	PMID:28189564
Biological Process	GO:1903902	positive regulation of viral life cycle	Kpna6	IMP	MGI:MGI:3856636	Mouse	PMID:28189564
Biological Process	GO:0006606	protein import into nucleus	Kpna6	IDA		Mouse	PMID:15689618
Biological Process	GO:0006366	transcription by RNA polymerase II	Kpna6	IMP	MGI:MGI:3856636	Mouse	PMID:21479251
Biological Process	GO:0019079	viral genome replication	Kpna6	IMP	MGI:MGI:3856636	Mouse	PMID:28189564

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern