Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KPNB1
  • Mouse genes Kpnb1
  • Rat genes Kpnb1
  • Zfish genes kpnb1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kpnb1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	KPNB1	IPI	UniProtKB:Q8N5Y8	Human	PMID:22701565
Molecular Function	GO:0051879	Hsp90 protein binding	Kpnb1	IDA		Mouse	PMID:19581287
Molecular Function	GO:0061676	importin-alpha family protein binding	Kpnb1	IPI	PR:C0LLJ0	Mouse	PMID:20699224
Molecular Function	GO:0061676	importin-alpha family protein binding	Kpnb1	IPI	PR:P52293	Mouse	PMID:20699224
Molecular Function	GO:0019894	kinesin binding	Kpnb1	IPI	RGD:1359118	Rat	PMID:16371587|RGD:9831193
Molecular Function	GO:0061608	nuclear import signal receptor activity	KPNB1	IDA		Human	PMID:14645851
Molecular Function	GO:0061608	nuclear import signal receptor activity	Kpnb1	IDA		Mouse	PMID:11809816
Molecular Function	GO:0061608	nuclear import signal receptor activity	Kpnb1	IDA		Mouse	PMID:15689618
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:O00505	Human	PMID:10523667
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:O00629	Human	PMID:10523667
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:O60684	Human	PMID:10523667
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:P52292	Human	PMID:10523667
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:P52294	Human	PMID:10523667
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:P52292	Human	PMID:11024021
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:P91276	Human	PMID:11311162
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:Q19969	Human	PMID:11311162
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:Q22560	Human	PMID:11311162
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:P03101	Human	PMID:11971900
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:P14907	Human	PMID:12372823
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:Q9BUP3	Human	PMID:15282309
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:O75940	Human	PMID:15494309
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:Q16637-3	Human	PMID:15494309
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:P03101	Human	PMID:15507604
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:P03107	Human	PMID:15507604
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:Q5VWG9	Human	PMID:15870280
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:Q7Z7C8	Human	PMID:15870280
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:P04626	Human	PMID:16314522
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:O96006	Human	PMID:17209048
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:P52292	Human	PMID:17596301
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:P52294	Human	PMID:17596301
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:P14907	Human	PMID:19680228
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:A9QM74	Human	PMID:20701745
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:P52292	Human	PMID:20701745
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:O00629	Human	PMID:20818336
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:Q8K4J6	Human	PMID:20818336
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:P49790	Human	PMID:21858095
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:Q2M3R5	Human	PMID:22084111
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:Q5TAQ9	Human	PMID:22500989
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:Q9WMX2	Human	PMID:24169621
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:Q14980	Human	PMID:26195665
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:A8CG34	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:O00505	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:O00629	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:O60684	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:O95373	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:P49790	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:P52292	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:P52294	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:P52292	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:Q6IQ23	Human	PMID:28877994
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:B3CRR2	Human	PMID:29734393
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:F5H1C8	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:P04233	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:Q15077	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:Q99558	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:Q9H1C4	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:Q9Y275	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:Q9NRI5	Human	PMID:31413325
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:A8CG34	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:O00505	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:O95373	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:P49790	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:P52292	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:Q6IQ23	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:Q9NRI5	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:P04620	Human	PMID:9405152
Molecular Function	GO:0005515	protein binding	KPNB1	IPI	UniProtKB:P52292	Human	PMID:9405152
Molecular Function	GO:0005515	protein binding	Kpnb1	IPI	UniProtKB:P62827	Mouse	MGI:MGI:5644193|PMID:25946333
Molecular Function	GO:0005515	protein binding	Kpnb1	IPI	UniProtKB:P49790	Mouse	MGI:MGI:6093040|PMID:18845677
Molecular Function	GO:0005515	protein binding	Kpnb1	IPI	PR:Q63850	Mouse	PMID:19581287
Molecular Function	GO:0005515	protein binding	Kpnb1	IPI	PR:P17679	Mouse	PMID:17548362
Molecular Function	GO:0005515	protein binding	Kpnb1	IPI	PR:P06537	Mouse	PMID:19581287
Molecular Function	GO:0005515	protein binding	Kpnb1	IPI	PR:P62827	Mouse	PMID:11809816
Molecular Function	GO:0005515	protein binding	Kpnb1	IPI	UniProtKB:Q6P1F4	Mouse	PMID:10891500
Molecular Function	GO:0005515	protein binding	Kpnb1	IPI	PR:Q08369	Mouse	PMID:17548362
Molecular Function	GO:0005515	protein binding	Kpnb1	IPI	UniProtKB:Q99J47	Mouse	PMID:28930673
Molecular Function	GO:0005515	protein binding	Kpnb1	IPI	PR:E9Q9D5	Mouse	PMID:23055941
Molecular Function	GO:0005515	protein binding	Kpnb1	IPI	PR:P52293	Mouse	PMID:15719015
Molecular Function	GO:0005515	protein binding	Kpnb1	IPI	RGD:71033	Rat	PMID:7604027|RGD:2316581
Molecular Function	GO:0005515	protein binding	Kpnb1	IPI	UniProtKB:P17955	Rat	PMID:8707840|RGD:633404
Molecular Function	GO:0005515	protein binding	Kpnb1	IPI	UniProtKB:P70581	Rat	PMID:8707840|RGD:633404
Molecular Function	GO:0005515	protein binding	Kpnb1	IPI	UniProtKB:P70582	Rat	PMID:8707840|RGD:633404
Molecular Function	GO:0005515	protein binding	Kpnb1	IPI	RGD:3216	Rat	PMID:9531546|RGD:10401199
Molecular Function	GO:0019904	protein domain specific binding	KPNB1	IPI	UniProtKB:Q99698	Human	PMID:11984006
Molecular Function	GO:0044877	protein-containing complex binding	Kpnb1	IPI	RGD:1560047|RGD:620367	Rat	PMID:9398662|RGD:9835011
Molecular Function	GO:0003723	RNA binding	KPNB1	HDA		Human	PMID:22681889
Cellular Component	GO:0005737	cytoplasm	KPNB1	IDA		Human	PMID:11891849
Cellular Component	GO:0010494	cytoplasmic stress granule	Kpnb1	IDA		Mouse	MGI:MGI:6148443|PMID:27430620
Cellular Component	GO:0005829	cytosol	KPNB1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0071782	endoplasmic reticulum tubular network	KPNB1	IDA		Human	PMID:22701565
Cellular Component	GO:0070062	extracellular exosome	KPNB1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	KPNB1	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	KPNB1	HDA		Human	PMID:23533145
Cellular Component	GO:0016020	membrane	KPNB1	HDA		Human	PMID:19946888
Cellular Component	GO:0042564	NLS-dependent protein nuclear import complex	KPNB1	IPI		Human	PMID:10353244
Cellular Component	GO:0042564	NLS-dependent protein nuclear import complex	KPNB1	IPI		Human	PMID:10523667
Cellular Component	GO:0042564	NLS-dependent protein nuclear import complex	KPNB1	IPI		Human	PMID:18187419
Cellular Component	GO:0042564	NLS-dependent protein nuclear import complex	KPNB1	IPI		Human	PMID:20701745
Cellular Component	GO:0042564	NLS-dependent protein nuclear import complex	KPNB1	IPI		Human	PMID:20818336
Cellular Component	GO:0005635	nuclear envelope	KPNB1	IDA		Human	PMID:22701565
Cellular Component	GO:0031965	nuclear membrane	KPNB1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005643	nuclear pore	Kpnb1	IDA		Rat	PMID:9398662|RGD:9835011
Cellular Component	GO:0005654	nucleoplasm	KPNB1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	KPNB1	IDA		Human	PMID:9670026
Cellular Component	GO:0032991	protein-containing complex	Kpnb1	IDA		Mouse	PMID:19796622
Biological Process	GO:0030953	astral microtubule organization	KPNB1	IMP		Human	PMID:23783028
Biological Process	GO:0040001	establishment of mitotic spindle localization	KPNB1	IMP		Human	PMID:23783028
Biological Process	GO:0045184	establishment of protein localization	KPNB1	IMP		Human	PMID:23783028
Biological Process	GO:0007079	mitotic chromosome movement towards spindle pole	KPNB1	IMP		Human	PMID:23783028
Biological Process	GO:0007080	mitotic metaphase plate congression	KPNB1	IMP		Human	PMID:23783028
Biological Process	GO:0090307	mitotic spindle assembly	KPNB1	IMP		Human	PMID:23783028
Biological Process	GO:0006607	NLS-bearing protein import into nucleus	KPNB1	IDA		Human	PMID:14645851
Biological Process	GO:0006606	protein import into nucleus	KPNB1	IDA		Human	PMID:15964792
Biological Process	GO:0006606	protein import into nucleus	KPNB1	IMP		Human	PMID:17209048
Biological Process	GO:0006606	protein import into nucleus	KPNB1	IDA		Human	PMID:20818336
Biological Process	GO:0006606	protein import into nucleus	KPNB1	IDA		Human	PMID:7615630
Biological Process	GO:0006606	protein import into nucleus	Kpnb1	IDA		Mouse	PMID:15689618
Biological Process	GO:0031291	Ran protein signal transduction	KPNB1	IMP		Human	PMID:23783028
Biological Process	GO:0006610	ribosomal protein import into nucleus	KPNB1	IDA		Human	PMID:9687515
Biological Process	GO:0006610	ribosomal protein import into nucleus	Kpnb1	IDA		Mouse	PMID:11809816
Biological Process	GO:0006404	RNA import into nucleus	KPNB1	IDA		Human	PMID:9670026

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern