Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KRT10
  • Mouse genes Krt10
  • Rat genes Krt10
  • Zfish genes cyt1,cyt1l,krt1-19d,krt15,krt17,krt91,krt92,krtt1c19e
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Krt10

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008092	cytoskeletal protein binding	Krt10	IGI	MGI:MGI:96699	Mouse	PMID:24751727
Molecular Function	GO:0005515	protein binding	KRT10	IPI	UniProtKB:A0A0H2URK1	Human	PMID:19627498
Molecular Function	GO:0005515	protein binding	KRT10	IPI	UniProtKB:P04264	Human	PMID:24940650
Molecular Function	GO:0005515	protein binding	KRT10	IPI	UniProtKB:Q15149	Human	PMID:24940650
Molecular Function	GO:0005515	protein binding	KRT10	IPI	UniProtKB:P04264	Human	PMID:27595935
Molecular Function	GO:0005515	protein binding	Krt10	IPI	UniProtKB:P04104|UniProtKB:Q9QXS1	Mouse	MGI:MGI:7260090|PMID:24940650
Molecular Function	GO:0005515	protein binding	Krt10	IPI	UniProtKB:Q60680-1	Mouse	MGI:MGI:3688344|PMID:15102471
Molecular Function	GO:0046982	protein heterodimerization activity	KRT10	IDA		Human	PMID:27595935
Molecular Function	GO:0030280	structural constituent of skin epidermis	KRT10	IDA		Human	PMID:7543090
Cellular Component	GO:0001533	cornified envelope	KRT10	IDA		Human	PMID:7543090
Cellular Component	GO:0001533	cornified envelope	Krt10	IDA		Mouse	PMID:26644517
Cellular Component	GO:0005737	cytoplasm	KRT10	IDA		Human	PMID:22170488
Cellular Component	GO:0005737	cytoplasm	KRT10	IDA		Human	PMID:32179842
Cellular Component	GO:0005737	cytoplasm	Krt10	IDA		Mouse	MGI:MGI:5603985|PMID:24751727
Cellular Component	GO:0070062	extracellular exosome	KRT10	HDA		Human	PMID:11487543
Cellular Component	GO:0070062	extracellular exosome	KRT10	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	KRT10	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	KRT10	HDA		Human	PMID:23580065
Cellular Component	GO:0045095	keratin filament	KRT10	IPI		Human	PMID:27595935
Cellular Component	GO:0045095	keratin filament	Krt10	IDA		Mouse	PMID:24751727
Cellular Component	GO:0045095	keratin filament	Krt10	IDA		Mouse	PMID:7679677
Cellular Component	GO:0045095	keratin filament	Krt10	IDA		Mouse	PMID:14673151
Cellular Component	GO:0016020	membrane	KRT10	HDA		Human	PMID:19946888
Cellular Component	GO:0005634	nucleus	KRT10	HDA		Human	PMID:21630459
Biological Process	GO:0042074	cell migration involved in gastrulation	cyt1	IMP	ZFIN:ZDB-MRPHLNO-080110-4	Zfish	PMID:17719025
Biological Process	GO:0071277	cellular response to calcium ion	Krt10	IDA		Mouse	PMID:19303854
Biological Process	GO:0008544	epidermis development	Krt10	IGI	MGI:MGI:96699	Mouse	PMID:24751727
Biological Process	GO:0031101	fin regeneration	krt17	IEP		Zfish	PMID:22278371
Biological Process	GO:0045109	intermediate filament organization	Krt10	IGI	MGI:MGI:96699	Mouse	PMID:24751727
Biological Process	GO:0003334	keratinocyte development	Krt10	IGI	MGI:MGI:96699	Mouse	PMID:24751727
Biological Process	GO:0030216	keratinocyte differentiation	KRT10	IEP		Human	PMID:22170488
Biological Process	GO:0030216	keratinocyte differentiation	Krt10	IDA		Mouse	PMID:19303854
Biological Process	GO:0018149	peptide cross-linking	KRT10	IDA		Human	PMID:7543090
Biological Process	GO:0045684	positive regulation of epidermis development	Krt10	IMP		Mouse	MGI:MGI:6107675|PMID:26603179
Biological Process	GO:0051290	protein heterotetramerization	KRT10	IDA		Human	PMID:27595935
Biological Process	GO:0048863	stem cell differentiation	Krt10	IDA		Mouse	PMID:19303854

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern