Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KRT16
  • Mouse genes Krt16
  • Rat genes Ka11,Krt16
  • Zfish genes cyt1,cyt1l,krt1-19d,krt15,krt17,krt91,krt92,krt96,krt97,krtt1c19e
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Krt16

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:Q9BT92	Human	PMID:15731013
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:A2BDD9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:O14964	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:O43790	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:O95295	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:O95983-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:O95995	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:P02538	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:P04264	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:P05787	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:P12035	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:P13647	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:P19013	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:P24863	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:P25800	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:P35908	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:P41219	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:P48668	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:P50151	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:P53365	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:P54646	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:P78385	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:P78386	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:Q01546	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:Q07002	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:Q14533	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:Q14CN4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:Q16512	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:Q3MIT2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:Q3SY84	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:Q5W5X9-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:Q5XKE5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:Q6KB66-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:Q6NYC8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:Q7L775	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:Q7RTS7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:Q86Y46-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:Q8IYE0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:Q8N1N4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:Q8N3L3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:Q8N6Y0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:Q8TAB5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:Q8TD31-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:Q969G3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:Q96ES7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:Q96GM5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:Q96LX7-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:Q99816	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:Q9BT92	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:Q9BVG8-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:Q9C0C4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:Q9H257-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:Q9NSK0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:Q9NX04	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:Q9UGP5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT16	IPI	UniProtKB:Q9UIA0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Krt16	IPI	UniProtKB:Q3U0V2	Mouse	MGI:MGI:3624581|PMID:16702408
Molecular Function	GO:0005200	structural constituent of cytoskeleton	Krt16	IDA		Mouse	PMID:12445204
Cellular Component	GO:0001533	cornified envelope	Krt16	IDA		Mouse	PMID:26644517
Cellular Component	GO:0005856	cytoskeleton	KRT16	IDA		Human	PMID:20403371
Cellular Component	GO:0070062	extracellular exosome	KRT16	HDA		Human	PMID:19199708
Cellular Component	GO:0005882	intermediate filament	Krt16	IDA		Mouse	PMID:12445204
Cellular Component	GO:0005634	nucleus	KRT16	HDA		Human	PMID:21630459
Biological Process	GO:0007568	aging	KRT16	IDA		Human	PMID:21916889
Biological Process	GO:0042074	cell migration involved in gastrulation	cyt1	IMP	ZFIN:ZDB-MRPHLNO-080110-4	Zfish	PMID:17719025
Biological Process	GO:0061436	establishment of skin barrier	Krt16	IMP		Mouse	MGI:MGI:5523704|PMID:24218583
Biological Process	GO:0031101	fin regeneration	krt17	IEP		Zfish	PMID:22278371
Biological Process	GO:0042633	hair cycle	KRT16	IDA		Human	PMID:21916889
Biological Process	GO:0006954	inflammatory response	Krt16	IMP		Mouse	MGI:MGI:5523704|PMID:24218583
Biological Process	GO:0045087	innate immune response	Krt16	IMP		Mouse	MGI:MGI:5523704|PMID:24218583
Biological Process	GO:0045104	intermediate filament cytoskeleton organization	Krt16	IDA		Mouse	PMID:12445204
Biological Process	GO:0031424	keratinization	Krt16	IDA		Mouse	MGI:MGI:5613485|PMID:11029038
Biological Process	GO:0030216	keratinocyte differentiation	Krt16	IDA		Mouse	MGI:MGI:5613485|PMID:11029038
Biological Process	GO:0051546	keratinocyte migration	Krt16	IDA		Mouse	MGI:MGI:5613485|PMID:11029038
Biological Process	GO:0002009	morphogenesis of an epithelium	Krt16	IMP		Mouse	MGI:MGI:5523704|PMID:24218583
Biological Process	GO:0030336	negative regulation of cell migration	KRT16	IDA		Human	PMID:20403371

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern