Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KYAT1
  • Mouse genes Kyat1
  • Rat genes Kyat1
  • Zfish genes kyat1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kyat1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0047804	cysteine-S-conjugate beta-lyase activity	KYAT1	IDA		Human	PMID:7883047
Molecular Function	GO:0047804	cysteine-S-conjugate beta-lyase activity	Kyat1	IDA		Rat	PMID:1723851|RGD:9685041
Molecular Function	GO:0047316	glutamine-phenylpyruvate transaminase activity	Kyat1	IDA		Rat	PMID:1723851|RGD:9685041
Molecular Function	GO:0016212	kynurenine-oxoglutarate transaminase activity	KYAT1	IDA		Human	PMID:19338303
Molecular Function	GO:0005515	protein binding	KYAT1	IPI	UniProtKB:Q08AM6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KYAT1	IPI	UniProtKB:Q15645	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KYAT1	IPI	UniProtKB:Q08AM6	Human	PMID:29892012
Molecular Function	GO:0042803	protein homodimerization activity	KYAT1	IPI	UniProtKB:Q16773	Human	PMID:15364907
Cellular Component	GO:0005829	cytosol	Kyat1	IDA		Rat	PMID:7796908|RGD:9685040
Cellular Component	GO:0005739	mitochondrion	Kyat1	IDA		Rat	PMID:7796908|RGD:9685040
Biological Process	GO:0070189	kynurenine metabolic process	KYAT1	IDA		Human	PMID:19338303
Biological Process	GO:0097052	L-kynurenine metabolic process	Kyat1	IDA		Rat	PMID:7796908|RGD:9685040
Biological Process	GO:0006090	pyruvate metabolic process	Kyat1	IDA		Rat	PMID:7796908|RGD:9685040
Biological Process	GO:0009617	response to bacterium	Kyat1	IEP		Mouse	PMID:23012479

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern