Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LACC1
  • Mouse genes Lacc1
  • Rat genes Lacc1
  • Zfish genes lacc1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lacc1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004000	adenosine deaminase activity	LACC1	IDA		Human	PMID:31978345
Molecular Function	GO:0047975	guanosine phosphorylase activity	LACC1	IDA		Human	PMID:31978345
Molecular Function	GO:0005515	protein binding	LACC1	IPI	UniProtKB:P49327	Human	PMID:27478939
Molecular Function	GO:0004731	purine-nucleoside phosphorylase activity	LACC1	IDA		Human	PMID:31978345
Molecular Function	GO:0017061	S-methyl-5-thioadenosine phosphorylase activity	LACC1	IDA		Human	PMID:31978345
Cellular Component	GO:0005737	cytoplasm	Lacc1	IDA		Mouse	MGI:MGI:6274082|PMID:30510070
Cellular Component	GO:0005783	endoplasmic reticulum	LACC1	IDA		Human	PMID:31875558
Cellular Component	GO:0005634	nucleus	Lacc1	IDA		Mouse	MGI:MGI:6274082|PMID:30510070
Cellular Component	GO:0005777	peroxisome	LACC1	IDA		Human	PMID:27478939
Cellular Component	GO:0005777	peroxisome	LACC1	IDA		Human	PMID:27959965
Biological Process	GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	LACC1	IDA		Human	PMID:31875558
Biological Process	GO:0002221	pattern recognition receptor signaling pathway	LACC1	IDA		Human	PMID:28593945
Biological Process	GO:0002221	pattern recognition receptor signaling pathway	LACC1	IDA		Human	PMID:31875558
Biological Process	GO:0002720	positive regulation of cytokine production involved in immune response	LACC1	IDA		Human	PMID:28593945
Biological Process	GO:0030641	regulation of cellular pH	LACC1	IDA		Human	PMID:31978345
Biological Process	GO:0050727	regulation of inflammatory response	Lacc1	IMP		Mouse	MGI:MGI:6274082|PMID:30510070
Biological Process	GO:1900542	regulation of purine nucleotide metabolic process	Lacc1	IMP		Mouse	MGI:MGI:6436442|PMID:31978345

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern