Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LAMA2
  • Mouse genes Lama2
  • Rat genes Lama2
  • Zfish genes lama2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lama2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Lama2	IPI	UniProtKB:Q62165	Mouse	PMID:24722207
Cellular Component	GO:0005604	basement membrane	LAMA2	IDA		Human	PMID:14557481
Cellular Component	GO:0005604	basement membrane	LAMA2	IDA		Human	PMID:2099832
Cellular Component	GO:0005604	basement membrane	Lama2	IDA		Mouse	PMID:15895400
Cellular Component	GO:0005604	basement membrane	Lama2	IDA		Mouse	PMID:9264260
Cellular Component	GO:0005604	basement membrane	Lama2	IDA		Mouse	PMID:18757743
Cellular Component	GO:0005604	basement membrane	Lama2	IDA		Mouse	PMID:12051813
Cellular Component	GO:0005604	basement membrane	Lama2	IDA		Mouse	PMID:9396756
Cellular Component	GO:0005604	basement membrane	Lama2	IDA		Mouse	PMID:9524190
Cellular Component	GO:0005604	basement membrane	Lama2	IDA		Rat	PMID:11271373|RGD:1600203
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LAMA2	HDA		Human	PMID:27068509
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LAMA2	HDA		Human	PMID:27559042
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LAMA2	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LAMA2	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Lama2	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Lama2	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0043197	dendritic spine	Lama2	IDA		Rat	PMID:9295190|RGD:1600208
Cellular Component	GO:0031594	neuromuscular junction	Lama2	IDA		Mouse	PMID:9396756
Cellular Component	GO:0042383	sarcolemma	Lama2	IDA		Mouse	PMID:11115849
Cellular Component	GO:0042383	sarcolemma	Lama2	IDA		Mouse	PMID:9524190
Cellular Component	GO:0043083	synaptic cleft	Lama2	IDA		Mouse	PMID:9396756
Biological Process	GO:0007411	axon guidance	Lama2	IGI	MGI:MGI:109613	Mouse	PMID:19295126
Biological Process	GO:0016203	muscle attachment	lama2	IGI	ZFIN:ZDB-GENO-070608-1,ZFIN:ZDB-GENO-080130-1	Zfish	PMID:22859503
Biological Process	GO:0016203	muscle attachment	lama2	IMP	ZFIN:ZDB-GENO-070608-1	Zfish	PMID:22859503
Biological Process	GO:0016203	muscle attachment	lama2	IGI	ZFIN:ZDB-GENO-070608-1,ZFIN:ZDB-GENO-091008-3	Zfish	PMID:22859503
Biological Process	GO:0016203	muscle attachment	lama2	IGI	ZFIN:ZDB-GENO-070608-1,ZFIN:ZDB-MRPHLNO-060119-6	Zfish	PMID:22859503
Biological Process	GO:0016203	muscle attachment	lama2	IGI	ZFIN:ZDB-GENO-070608-1,ZFIN:ZDB-GENO-100507-10	Zfish	PMID:22859503
Biological Process	GO:0007517	muscle organ development	lama2	IMP	ZFIN:ZDB-MRPHLNO-060119-5	Zfish	PMID:16321372
Biological Process	GO:0007517	muscle organ development	lama2	IMP	ZFIN:ZDB-GENO-110805-7	Zfish	PMID:21531457
Biological Process	GO:0022011	myelination in peripheral nervous system	lama2	IGI	ZFIN:ZDB-GENO-090917-2,ZFIN:ZDB-MRPHLNO-060119-5	Zfish	PMID:25695270
Biological Process	GO:0032224	positive regulation of synaptic transmission, cholinergic	Lama2	IMP	MGI:MGI:1856026	Mouse	PMID:8568931
Biological Process	GO:0014037	Schwann cell differentiation	Lama2	IEP		Rat	PMID:11869039|RGD:1600202
Biological Process	GO:0060538	skeletal muscle organ development	lama2	IMP	ZFIN:ZDB-GENO-070608-1	Zfish	PMID:28241031
Biological Process	GO:0060538	skeletal muscle organ development	lama2	IMP	ZFIN:ZDB-GENO-110817-5	Zfish	PMID:22952766
Biological Process	GO:0060538	skeletal muscle organ development	lama2	IMP	ZFIN:ZDB-GENO-170615-2	Zfish	PMID:28241031

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern