Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LAMA4
  • Mouse genes Lama4
  • Rat genes Lama4
  • Zfish genes lama4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lama4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Cellular Component	GO:0005604	basement membrane	LAMA4	IDA		Human	PMID:14557481
Cellular Component	GO:0005604	basement membrane	Lama4	IDA		Mouse	PMID:9396756
Cellular Component	GO:0005604	basement membrane	Lama4	IDA		Mouse	PMID:15895400
Cellular Component	GO:0005604	basement membrane	Lama4	IDA		Mouse	PMID:9346933
Cellular Component	GO:0005604	basement membrane	Lama4	IDA		Mouse	PMID:9614228
Cellular Component	GO:0005604	basement membrane	Lama4	IDA		Mouse	PMID:18757743
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LAMA4	HDA		Human	PMID:27068509
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LAMA4	HDA		Human	PMID:27559042
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LAMA4	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LAMA4	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Lama4	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Lama4	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0070062	extracellular exosome	LAMA4	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	LAMA4	HDA		Human	PMID:21362503
Cellular Component	GO:0031594	neuromuscular junction	Lama4	IDA		Mouse	PMID:9396756
Cellular Component	GO:0043083	synaptic cleft	Lama4	IDA		Mouse	PMID:9396756
Biological Process	GO:0001568	blood vessel development	Lama4	IMP	MGI:MGI:2179127	Mouse	PMID:11809810
Biological Process	GO:0048514	blood vessel morphogenesis	lama4	IGI	ZFIN:ZDB-GENO-980202-249,ZFIN:ZDB-MRPHLNO-060119-6	Zfish	PMID:16321372
Biological Process	GO:0048514	blood vessel morphogenesis	lama4	IGI	ZFIN:ZDB-MRPHLNO-060119-1,ZFIN:ZDB-MRPHLNO-060119-6	Zfish	PMID:16321372
Biological Process	GO:0050873	brown fat cell differentiation	Lama4	IDA		Mouse	PMID:18492766
Biological Process	GO:0001885	endothelial cell development	lama4	IGI	ZFIN:ZDB-GENO-080130-1,ZFIN:ZDB-MRPHLNO-060119-6	Zfish	PMID:17646580
Biological Process	GO:0016203	muscle attachment	lama4	IGI	ZFIN:ZDB-GENO-070608-1,ZFIN:ZDB-MRPHLNO-060119-6	Zfish	PMID:22859503
Biological Process	GO:0016203	muscle attachment	lama4	IMP	ZFIN:ZDB-MRPHLNO-060119-6	Zfish	PMID:18436206
Biological Process	GO:0120163	negative regulation of cold-induced thermogenesis	Lama4	IMP		Mouse	MGI:MGI:6100984|PMID:28973559
Biological Process	GO:0030903	notochord development	lama4	IGI	ZFIN:ZDB-MRPHLNO-060119-1,ZFIN:ZDB-MRPHLNO-060119-6	Zfish	PMID:16321372
Biological Process	GO:0030903	notochord development	lama4	IGI	ZFIN:ZDB-GENO-980202-249,ZFIN:ZDB-MRPHLNO-060119-6	Zfish	PMID:16321372

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern