Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LAMA5
  • Mouse genes Lama5
  • Rat genes Lama5
  • Zfish genes lama5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lama5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005178	integrin binding	LAMA5	IDA		Human	PMID:11821406
Molecular Function	GO:0005178	integrin binding	Lama5	IDA		Mouse	PMID:11741585
Molecular Function	GO:0005515	protein binding	Lama5	IPI	PR:P02468	Mouse	PMID:12743034
Molecular Function	GO:0005515	protein binding	Lama5	IPI	PR:P02469	Mouse	PMID:12743034
Cellular Component	GO:0005604	basement membrane	LAMA5	IDA		Human	PMID:14557481
Cellular Component	GO:0005604	basement membrane	Lama5	IDA		Mouse	PMID:10651091
Cellular Component	GO:0005604	basement membrane	Lama5	IDA		Mouse	PMID:14568553
Cellular Component	GO:0005604	basement membrane	Lama5	IDA		Mouse	PMID:15895400
Cellular Component	GO:0005604	basement membrane	Lama5	IDA		Mouse	PMID:9396756
Cellular Component	GO:0005604	basement membrane	Lama5	IDA		Mouse	PMID:12743034
Cellular Component	GO:0005604	basement membrane	Lama5	IDA		Mouse	PMID:11507772
Cellular Component	GO:0005604	basement membrane	Lama5	IDA		Mouse	PMID:8707838
Cellular Component	GO:0005604	basement membrane	Lama5	IDA		Mouse	PMID:9299121
Cellular Component	GO:0005604	basement membrane	Lama5	IDA		Mouse	PMID:22665518
Cellular Component	GO:0005604	basement membrane	Lama5	IDA		Mouse	PMID:9735344
Cellular Component	GO:0005604	basement membrane	Lama5	IDA		Mouse	PMID:16886065
Cellular Component	GO:0005604	basement membrane	Lama5	IDA		Mouse	PMID:18757743
Cellular Component	GO:0005604	basement membrane	Lama5	IDA		Mouse	PMID:12051813
Cellular Component	GO:0005604	basement membrane	Lama5	IDA		Mouse	PMID:19651211
Cellular Component	GO:0005604	basement membrane	Lama5	IDA		Mouse	PMID:12921739
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LAMA5	HDA		Human	PMID:20551380
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LAMA5	HDA		Human	PMID:23658023
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LAMA5	HDA		Human	PMID:27068509
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LAMA5	HDA		Human	PMID:27559042
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LAMA5	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LAMA5	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Lama5	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Lama5	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0070062	extracellular exosome	LAMA5	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	LAMA5	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	LAMA5	HDA		Human	PMID:23533145
Cellular Component	GO:0031012	extracellular matrix	Lama5	IDA		Mouse	PMID:16554364
Cellular Component	GO:0098965	extracellular matrix of synaptic cleft	Lama5	IDA		Mouse	PMID:29091766
Cellular Component	GO:0098965	extracellular matrix of synaptic cleft	Lama5	IMP		Mouse	PMID:29091766
Cellular Component	GO:0098965	extracellular matrix of synaptic cleft	Lama5	IEP		Mouse	PMID:29091766
Cellular Component	GO:0005615	extracellular space	LAMA5	IDA		Human	PMID:10964500
Cellular Component	GO:0098978	glutamatergic synapse	Lama5	IDA		Mouse	PMID:29091766
Cellular Component	GO:0098978	glutamatergic synapse	Lama5	IMP		Mouse	PMID:29091766
Cellular Component	GO:0098978	glutamatergic synapse	Lama5	IEP		Mouse	PMID:29091766
Cellular Component	GO:0043259	laminin-10 complex	LAMA5	IDA		Human	PMID:10964500
Cellular Component	GO:0043259	laminin-10 complex	Lama5	IPI	PR:P02469	Mouse	PMID:9299121
Cellular Component	GO:0043259	laminin-10 complex	Lama5	IPI	PR:P02468	Mouse	PMID:9299121
Cellular Component	GO:0005610	laminin-5 complex	Lama5	IDA		Rat	PMID:9417868|RGD:633095
Cellular Component	GO:0031594	neuromuscular junction	Lama5	IDA		Mouse	PMID:9396756
Cellular Component	GO:0005634	nucleus	LAMA5	HDA		Human	PMID:21630459
Cellular Component	GO:0043083	synaptic cleft	Lama5	IDA		Mouse	PMID:9396756
Biological Process	GO:0009887	animal organ morphogenesis	Lama5	IMP	MGI:MGI:1934917	Mouse	PMID:12743034
Biological Process	GO:0060445	branching involved in salivary gland morphogenesis	Lama5	IMP		Mouse	PMID:14568553
Biological Process	GO:0001658	branching involved in ureteric bud morphogenesis	Lama5	IMP		Mouse	PMID:14568553
Biological Process	GO:0048754	branching morphogenesis of an epithelial tube	Lama5	IMP		Mouse	PMID:14568553
Biological Process	GO:0016477	cell migration	LAMA5	IDA		Human	PMID:11821406
Biological Process	GO:0098609	cell-cell adhesion	lama5	IMP	ZFIN:ZDB-GENO-080109-2	Zfish	PMID:17919534
Biological Process	GO:0060271	cilium assembly	Lama5	IMP	MGI:MGI:1934917	Mouse	PMID:16365040
Biological Process	GO:0033333	fin development	lama5	IMP		Zfish	PMID:9007245
Biological Process	GO:0033334	fin morphogenesis	lama5	IMP	ZFIN:ZDB-GENO-100528-9	Zfish	PMID:20419147
Biological Process	GO:0001942	hair follicle development	Lama5	IMP	MGI:MGI:1934917	Mouse	PMID:18676816
Biological Process	GO:0007229	integrin-mediated signaling pathway	LAMA5	IMP		Human	PMID:11821406
Biological Process	GO:0001822	kidney development	Lama5	IMP	MGI:MGI:5646299	Mouse	PMID:27002738
Biological Process	GO:0030324	lung development	Lama5	IMP	MGI:MGI:1934917	Mouse	PMID:12051813
Biological Process	GO:0035141	medial fin morphogenesis	lama5	IMP	ZFIN:ZDB-GENO-080109-2	Zfish	PMID:17919534
Biological Process	GO:0035141	medial fin morphogenesis	lama5	IMP	ZFIN:ZDB-MRPHLNO-080109-7	Zfish	PMID:17919534
Biological Process	GO:0001738	morphogenesis of a polarized epithelium	Lama5	IMP	MGI:MGI:1934917	Mouse	PMID:16365040
Biological Process	GO:0016331	morphogenesis of embryonic epithelium	Lama5	IMP	MGI:MGI:1934917	Mouse	PMID:16365040
Biological Process	GO:0007517	muscle organ development	Lama5	IMP	MGI:MGI:1934917	Mouse	PMID:12921739
Biological Process	GO:0001755	neural crest cell migration	Lama5	IMP	MGI:MGI:1934917	Mouse	PMID:16316641
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	Lama5	IMP	MGI:MGI:1934917	Mouse	PMID:16365040
Biological Process	GO:0035138	pectoral fin morphogenesis	lama5	IMP	ZFIN:ZDB-GENO-080109-2	Zfish	PMID:17919534
Biological Process	GO:0099173	postsynapse organization	Lama5	IDA		Mouse	PMID:29091766
Biological Process	GO:0099173	postsynapse organization	Lama5	IMP		Mouse	PMID:29091766
Biological Process	GO:0008104	protein localization	lama5	IMP	ZFIN:ZDB-GENO-080109-2	Zfish	PMID:17919534
Biological Process	GO:0072659	protein localization to plasma membrane	Lama5	IMP	MGI:MGI:1934917	Mouse	PMID:11507772
Biological Process	GO:0050678	regulation of epithelial cell proliferation	Lama5	IMP	MGI:MGI:1934917	Mouse	PMID:16365040
Biological Process	GO:0048705	skeletal system morphogenesis	LAMA5	IMP		Human	PMID:33242826
Biological Process	GO:0034446	substrate adhesion-dependent cell spreading	LAMA5	IDA		Human	PMID:16236823
Biological Process	GO:0036484	trunk neural crest cell migration	Lama5	IMP	MGI:MGI:1934917	Mouse	PMID:16316641

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern