Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LAMB2
  • Mouse genes Lamb2
  • Rat genes Lamb2
  • Zfish genes lamb2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lamb2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005178	integrin binding	Lamb2	IPI	PR:Q61738	Mouse	PMID:20566382
Molecular Function	GO:0005178	integrin binding	Lamb2	IPI	PR:P09055	Mouse	PMID:20566382
Molecular Function	GO:0005178	integrin binding	Lamb2	IPI	PR:Q61739	Mouse	PMID:20566382
Molecular Function	GO:0005515	protein binding	LAMB2	IPI	UniProtKB:Q969E8	Human	PMID:32296183
Molecular Function	GO:0150043	structural constituent of synapse-associated extracellular matrix	Lamb2	IDA		Mouse	PMID:17189701
Molecular Function	GO:0150043	structural constituent of synapse-associated extracellular matrix	Lamb2	IMP		Mouse	PMID:17189701
Molecular Function	GO:0150043	structural constituent of synapse-associated extracellular matrix	Lamb2	IEP		Mouse	PMID:17189701
Cellular Component	GO:0005604	basement membrane	LAMB2	IDA		Human	PMID:10964500
Cellular Component	GO:0005604	basement membrane	LAMB2	IDA		Human	PMID:14557481
Cellular Component	GO:0005604	basement membrane	LAMB2	IDA		Human	PMID:2099832
Cellular Component	GO:0005604	basement membrane	Lamb2	IDA		Mouse	MGI:MGI:3776221|PMID:16041630
Cellular Component	GO:0005604	basement membrane	Lamb2	IDA		Mouse	PMID:7670489
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LAMB2	HDA		Human	PMID:20551380
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LAMB2	HDA		Human	PMID:27068509
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LAMB2	HDA		Human	PMID:27559042
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LAMB2	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LAMB2	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Lamb2	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Lamb2	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0070062	extracellular exosome	LAMB2	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	LAMB2	HDA		Human	PMID:23533145
Cellular Component	GO:0043256	laminin complex	Lamb2	IDA		Mouse	PMID:8034675
Cellular Component	GO:0005608	laminin-3 complex	LAMB2	IPI	UniProtKB:P25391	Human	PMID:10964500
Cellular Component	GO:0005608	laminin-3 complex	Lamb2	IDA		Mouse	PMID:20566382
Cellular Component	GO:0031594	neuromuscular junction	Lamb2	IDA		Mouse	PMID:9396756
Cellular Component	GO:0045202	synapse	Lamb2	IDA		Mouse	PMID:17189701
Cellular Component	GO:0043083	synaptic cleft	Lamb2	IDA		Mouse	PMID:9396756
Biological Process	GO:0014002	astrocyte development	Lamb2	IGI	MGI:MGI:1344394	Mouse	PMID:19907020
Biological Process	GO:0048677	axon extension involved in regeneration	Lamb2	IMP	MGI:MGI:1856026	Mouse	PMID:9396756
Biological Process	GO:0007411	axon guidance	Lamb2	IGI	MGI:MGI:109613	Mouse	PMID:19295126
Biological Process	GO:0070831	basement membrane assembly	lamb2	IMP	ZFIN:ZDB-MRPHLNO-091008-3	Zfish	PMID:19736328
Biological Process	GO:0070831	basement membrane assembly	lamb2	IMP	ZFIN:ZDB-GENO-980202-1174	Zfish	PMID:19736328
Biological Process	GO:0000904	cell morphogenesis involved in differentiation	Lamb2	IGI	MGI:MGI:1344394	Mouse	PMID:19907020
Biological Process	GO:0021782	glial cell development	lamb2	IMP	ZFIN:ZDB-CRISPR-191008-15,ZFIN:ZDB-CRISPR-191008-16	Zfish	PMID:30924555
Biological Process	GO:0072274	metanephric glomerular basement membrane development	Lamb2	IMP	MGI:MGI:2138070	Mouse	PMID:7670489
Biological Process	GO:0072274	metanephric glomerular basement membrane development	Lamb2	IMP	MGI:MGI:2138070	Mouse	PMID:16886065
Biological Process	GO:0072249	metanephric podocyte development	Lamb2	IMP	MGI:MGI:2138070	Mouse	PMID:16886065
Biological Process	GO:0016203	muscle attachment	lamb2	IMP	ZFIN:ZDB-GENO-980202-1174	Zfish	PMID:19736328
Biological Process	GO:0016203	muscle attachment	lamb2	IMP	ZFIN:ZDB-MRPHLNO-091008-3	Zfish	PMID:19736328
Biological Process	GO:0007528	neuromuscular junction development	Lamb2	IMP	MGI:MGI:2138070	Mouse	PMID:7885444
Biological Process	GO:0007528	neuromuscular junction development	Lamb2	IMP	MGI:MGI:2138070	Mouse	PMID:17418794
Biological Process	GO:0031175	neuron projection development	Lamb2	IDA		Mouse	PMID:20566382
Biological Process	GO:0060041	retina development in camera-type eye	Lamb2	IGI	MGI:MGI:1344394	Mouse	PMID:19907020
Biological Process	GO:0060041	retina development in camera-type eye	lamb2	IMP	ZFIN:ZDB-CRISPR-191008-15,ZFIN:ZDB-CRISPR-191008-16	Zfish	PMID:30924555
Biological Process	GO:0014044	Schwann cell development	Lamb2	IDA		Mouse	PMID:9641682
Biological Process	GO:0061053	somite development	lamb2	IMP	ZFIN:ZDB-GENO-121101-2	Zfish	PMID:22713473
Biological Process	GO:0050808	synapse organization	Lamb2	IMP	MGI:MGI:2138070	Mouse	PMID:17189701
Biological Process	GO:0007601	visual perception	Lamb2	IGI	MGI:MGI:1344394	Mouse	PMID:19907020

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern