Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Lamp1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes LAMP1
- Mouse genes Lamp1
- Rat genes Lamp1
- Zfish genes lamp1a,lamp1b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lamp1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	LAMP1	IPI	UniProtKB:Q9NP78	Human	PMID:22641697
Molecular Function	GO:0005515	protein binding	LAMP1	IPI	UniProtKB:Q9NP78	Human	PMID:21194361
Molecular Function	GO:0005515	protein binding	LAMP1	IPI	UniProtKB:Q5VZM2	Human	PMID:23394946
Molecular Function	GO:0005515	protein binding	LAMP1	IPI	UniProtKB:P08669	Human	PMID:24970085
Molecular Function	GO:0005515	protein binding	LAMP1	IPI	UniProtKB:Q6P1K1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LAMP1	IPI	UniProtKB:Q6UX27-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Lamp1	IPI	UniProtKB:P63277	Mouse	MGI:MGI:3828400\|PMID:16674683
Molecular Function	GO:0005515	protein binding	Lamp1	IPI	UniProtKB:Q9NP78	Mouse	MGI:MGI:6695860\|PMID:21194361
Molecular Function	GO:0019904	protein domain specific binding	Lamp1	IPI	UniProtKB:Q9NP78	Mouse	MGI:MGI:5499709\|PMID:22641697
Cellular Component	GO:0097208	alveolar lamellar body	Lamp1	IDA		Rat	PMID:7868367\|RGD:4892636
Cellular Component	GO:0044754	autolysosome	Lamp1	IDA		Mouse	PMID:26284655
Cellular Component	GO:0000421	autophagosome membrane	Lamp1	IDA		Mouse	PMID:31006538
Cellular Component	GO:0009986	cell surface	Lamp1	IDA		Mouse	MGI:MGI:3828400\|PMID:16674683
Cellular Component	GO:0044194	cytolytic granule	Lamp1	IDA		Mouse	MGI:MGI:6506882\|PMID:32839608
Cellular Component	GO:0044194	cytolytic granule	Lamp1	IDA		Mouse	PMID:19915045
Cellular Component	GO:0101004	cytolytic granule membrane	LAMP1	IDA		Human	PMID:24088571
Cellular Component	GO:0005737	cytoplasm	LAMP1	IDA		Human	PMID:21266579
Cellular Component	GO:0031410	cytoplasmic vesicle	Lamp1	IDA		Rat	PMID:18690537\|RGD:4892631
Cellular Component	GO:0030425	dendrite	Lamp1	IDA		Rat	PMID:20410104\|RGD:8553482
Cellular Component	GO:0005768	endosome	Lamp1	IDA		Mouse	PMID:10787428
Cellular Component	GO:0005768	endosome	Lamp1	IDA		Mouse	PMID:31637311
Cellular Component	GO:0005768	endosome	Lamp1	IDA		Mouse	PMID:11182090
Cellular Component	GO:0009897	external side of plasma membrane	Lamp1	IDA		Mouse	PMID:16973387
Cellular Component	GO:0070062	extracellular exosome	LAMP1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	LAMP1	HDA		Human	PMID:23533145
Cellular Component	GO:0005770	late endosome	LAMP1	IDA		Human	PMID:15052268
Cellular Component	GO:0005770	late endosome	LAMP1	IDA		Human	PMID:15292400
Cellular Component	GO:0005770	late endosome	LAMP1	IDA		Human	PMID:15792797
Cellular Component	GO:0005770	late endosome	LAMP1	IDA		Human	PMID:16542649
Cellular Component	GO:0005770	late endosome	LAMP1	IDA		Human	PMID:18388320
Cellular Component	GO:0005770	late endosome	LAMP1	IDA		Human	PMID:18767904
Cellular Component	GO:0005770	late endosome	Lamp1	IDA		Mouse	PMID:14668490
Cellular Component	GO:0005770	late endosome	Lamp1	IDA		Mouse	PMID:24841562
Cellular Component	GO:0005770	late endosome	Lamp1	IDA		Mouse	PMID:16415873
Cellular Component	GO:0005770	late endosome	Lamp1	IDA		Mouse	PMID:17620357
Cellular Component	GO:0005770	late endosome	Lamp1	IDA		Mouse	PMID:18477453
Cellular Component	GO:0005770	late endosome	Lamp1	IDA		Mouse	PMID:15294975
Cellular Component	GO:0005770	late endosome	Lamp1	IDA		Mouse	PMID:12446704
Cellular Component	GO:0005764	lysosome	LAMP1	IDA		Human	PMID:15613468
Cellular Component	GO:0005764	lysosome	LAMP1	IDA		Human	PMID:15052268
Cellular Component	GO:0005764	lysosome	LAMP1	IDA		Human	PMID:15292400
Cellular Component	GO:0005764	lysosome	LAMP1	IDA		Human	PMID:16542649
Cellular Component	GO:0005764	lysosome	LAMP1	IDA		Human	PMID:22792322
Cellular Component	GO:0005764	lysosome	LAMP1	IDA		Human	PMID:23704327
Cellular Component	GO:0005764	lysosome	Lamp1	IDA		Mouse	PMID:17185018
Cellular Component	GO:0005764	lysosome	Lamp1	IDA		Mouse	PMID:24035762
Cellular Component	GO:0005764	lysosome	Lamp1	IDA		Mouse	PMID:31637311
Cellular Component	GO:0005764	lysosome	Lamp1	IDA		Mouse	PMID:15006695
Cellular Component	GO:0005764	lysosome	Lamp1	IDA		Mouse	PMID:14627652
Cellular Component	GO:0005764	lysosome	Lamp1	IDA		Mouse	PMID:10787428
Cellular Component	GO:0005764	lysosome	Lamp1	IDA		Mouse	PMID:11854359
Cellular Component	GO:0005764	lysosome	Lamp1	IDA		Mouse	PMID:16542649
Cellular Component	GO:0005764	lysosome	Lamp1	IDA		Mouse	PMID:23926254
Cellular Component	GO:0005764	lysosome	Lamp1	IDA		Mouse	PMID:15588329
Cellular Component	GO:0005764	lysosome	Lamp1	IDA		Mouse	PMID:26965651
Cellular Component	GO:0005764	lysosome	Lamp1	IDA		Mouse	PMID:18477453
Cellular Component	GO:0005764	lysosome	Lamp1	IDA		Mouse	PMID:11486041
Cellular Component	GO:0005764	lysosome	Lamp1	IDA		Mouse	PMID:24029230
Cellular Component	GO:0005764	lysosome	Lamp1	IDA		Mouse	PMID:15294975
Cellular Component	GO:0005764	lysosome	Lamp1	IDA		Mouse	PMID:14643301
Cellular Component	GO:0005764	lysosome	Lamp1	IDA		Mouse	PMID:16415873
Cellular Component	GO:0005764	lysosome	Lamp1	IDA		Mouse	PMID:12925704
Cellular Component	GO:0005764	lysosome	Lamp1	IDA		Mouse	PMID:26432893
Cellular Component	GO:0005764	lysosome	Lamp1	IDA		Rat	PMID:15469932\|RGD:15090831
Cellular Component	GO:0042470	melanosome	Lamp1	IDA		Mouse	PMID:11266470
Cellular Component	GO:0016020	membrane	LAMP1	HDA		Human	PMID:19946888
Cellular Component	GO:0005771	multivesicular body	Lamp1	IDA		Mouse	PMID:11854359
Cellular Component	GO:0005771	multivesicular body	Lamp1	IDA		Rat	PMID:7868367\|RGD:4892636
Cellular Component	GO:0043025	neuronal cell body	Lamp1	IDA		Rat	PMID:20410104\|RGD:8553482
Cellular Component	GO:0048471	perinuclear region of cytoplasm	LAMP1	IMP		Human	PMID:18787122
Cellular Component	GO:0045335	phagocytic vesicle	Lamp1	IMP		Mouse	MGI:MGI:5634883\|PMID:22190682
Cellular Component	GO:0061474	phagolysosome membrane	Lamp1	IDA		Mouse	PMID:23395172
Cellular Component	GO:0005886	plasma membrane	LAMP1	IDA		Human	PMID:20956541
Cellular Component	GO:0042383	sarcolemma	Lamp1	IDA		Mouse	PMID:14506282
Cellular Component	GO:0008021	synaptic vesicle	Lamp1	IDA		Mouse	PMID:15073168
Cellular Component	GO:0030672	synaptic vesicle membrane	Lamp1	EXP		Rat	PMID:17110340\|RGD:12050113
Cellular Component	GO:0030672	synaptic vesicle membrane	Lamp1	IDA		Rat	PMID:17110340\|RGD:12050113
Cellular Component	GO:0005773	vacuole	Lamp1	IDA		Rat	PMID:22147702\|RGD:7247589
Cellular Component	GO:0031982	vesicle	Lamp1	IDA		Mouse	PMID:10787428
Biological Process	GO:0048102	autophagic cell death	Lamp1	IDA		Rat	PMID:18690537\|RGD:4892631
Biological Process	GO:0072594	establishment of protein localization to organelle	LAMP1	IMP		Human	PMID:23632890
Biological Process	GO:0090160	Golgi to lysosome transport	LAMP1	IMP		Human	PMID:23632890
Biological Process	GO:0140507	granzyme-mediated programmed cell death signaling pathway	LAMP1	IMP		Human	PMID:23632890
Biological Process	GO:0043323	positive regulation of natural killer cell degranulation	LAMP1	IMP		Human	PMID:23632890
Biological Process	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	LAMP1	IMP		Human	PMID:23632890
Biological Process	GO:0050821	protein stabilization	Lamp1	IMP		Mouse	MGI:MGI:5499709\|PMID:22641697
Biological Process	GO:1902513	regulation of organelle transport along microtubule	LAMP1	IMP		Human	PMID:23632890

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/24/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.