Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LAMP3
  • Mouse genes Lamp3
  • Rat genes Lamp3
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lamp3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Cellular Component	GO:0097233	alveolar lamellar body membrane	Lamp3	IDA		Mouse	PMID:14982840
Cellular Component	GO:0097233	alveolar lamellar body membrane	Lamp3	IDA		Rat	PMID:20054147|RGD:11041051
Cellular Component	GO:0005769	early endosome	LAMP3	IDA		Human	PMID:21810281
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	LAMP3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005765	lysosomal membrane	Lamp3	IDA		Mouse	PMID:12938238
Cellular Component	GO:0005764	lysosome	Lamp3	IDA		Mouse	PMID:23395172
Cellular Component	GO:0048471	perinuclear region of cytoplasm	LAMP3	IDA		Human	PMID:25681212
Cellular Component	GO:0005886	plasma membrane	LAMP3	IDA		Human	PMID:21810281
Cellular Component	GO:0031982	vesicle	LAMP3	IDA		Human	PMID:25681212
Biological Process	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	LAMP3	IMP		Human	PMID:25681212
Biological Process	GO:1901799	negative regulation of proteasomal protein catabolic process	LAMP3	IMP		Human	PMID:25681212
Biological Process	GO:0010628	positive regulation of gene expression	LAMP3	IMP		Human	PMID:23651994
Biological Process	GO:0010506	regulation of autophagy	LAMP3	IMP		Human	PMID:25681212
Biological Process	GO:1903900	regulation of viral life cycle	LAMP3	IMP		Human	PMID:21810281
Biological Process	GO:0035455	response to interferon-alpha	LAMP3	IMP		Human	PMID:23651994

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern