Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LAMTOR1
  • Mouse genes Lamtor1
  • Rat genes LOC100361543,Lamtor1
  • Zfish genes lamtor1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lamtor1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051020	GTPase binding	LAMTOR1	IPI	UniProtKB:Q5VZM2,UniProtKB:Q9HB90	Human	PMID:22424946
Molecular Function	GO:0051020	GTPase binding	LAMTOR1	IPI	UniProtKB:Q5VZM2,UniProtKB:Q9NQL2	Human	PMID:22424946
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	LAMTOR1	IDA		Human	PMID:22980980
Molecular Function	GO:0060090	molecular adaptor activity	LAMTOR1	IDA		Human	PMID:22980980
Molecular Function	GO:0005515	protein binding	LAMTOR1	IPI	UniProtKB:Q5VZM2	Human	PMID:20381137
Molecular Function	GO:0005515	protein binding	LAMTOR1	IPI	UniProtKB:Q9NQL2	Human	PMID:20381137
Molecular Function	GO:0005515	protein binding	LAMTOR1	IPI	UniProtKB:Q9Y2Q5	Human	PMID:20381137
Molecular Function	GO:0005515	protein binding	LAMTOR1	IPI	UniProtKB:Q7L523	Human	PMID:22980980
Molecular Function	GO:0005515	protein binding	LAMTOR1	IPI	UniProtKB:Q9Y2Q5	Human	PMID:22980980
Molecular Function	GO:0005515	protein binding	LAMTOR1	IPI	UniProtKB:Q7L523	Human	PMID:25561175
Molecular Function	GO:0005515	protein binding	LAMTOR1	IPI	UniProtKB:Q8NBW4	Human	PMID:25561175
Molecular Function	GO:0005515	protein binding	LAMTOR1	IPI	UniProtKB:Q9Y2Q5	Human	PMID:25561175
Molecular Function	GO:0005515	protein binding	LAMTOR1	IPI	UniProtKB:Q7L523	Human	PMID:25567906
Molecular Function	GO:0005515	protein binding	LAMTOR1	IPI	UniProtKB:Q8NBW4	Human	PMID:25567906
Molecular Function	GO:0005515	protein binding	LAMTOR1	IPI	UniProtKB:Q9Y2Q5	Human	PMID:25567906
Molecular Function	GO:0005515	protein binding	LAMTOR1	IPI	UniProtKB:O15118,UniProtKB:Q7L523,UniProtKB:Q8NBW4,UniProtKB:Q9HB90	Human	PMID:28336668
Molecular Function	GO:0005515	protein binding	LAMTOR1	IPI	UniProtKB:Q9Y2Q5	Human	PMID:29123114
Molecular Function	GO:0005515	protein binding	LAMTOR1	IPI	UniProtKB:Q86T03	Human	PMID:29644770
Molecular Function	GO:0005515	protein binding	LAMTOR1	IPI	UniProtKB:P78358	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LAMTOR1	IPI	UniProtKB:P06396	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LAMTOR1	IPI	UniProtKB:P08670	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LAMTOR1	IPI	UniProtKB:P16284	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LAMTOR1	IPI	UniProtKB:P20339	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LAMTOR1	IPI	UniProtKB:P22607	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LAMTOR1	IPI	UniProtKB:P28329-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LAMTOR1	IPI	UniProtKB:P61086	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LAMTOR1	IPI	UniProtKB:Q9UMX0	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LAMTOR1	IPI	UniProtKB:Q9Y649	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Lamtor1	IPI	UniProtKB:Q3TWL2	Mouse	MGI:MGI:6304515|PMID:29644770
Molecular Function	GO:0005515	protein binding	Lamtor1	IPI	UniProtKB:O88653|UniProtKB:Q9JHS3	Mouse	MGI:MGI:4887551|PMID:19177150
Molecular Function	GO:0005515	protein binding	Lamtor1	IPI	PR:Q9JKF1	Mouse	PMID:24841562
Molecular Function	GO:0005515	protein binding	LOC100361543	IPI	UniProtKB:O88653	Rat	PMID:19177150|RGD:8553879
Molecular Function	GO:0005515	protein binding	LOC100361543	IPI	UniProtKB:Q5U204	Rat	PMID:19177150|RGD:8553879
Molecular Function	GO:0005515	protein binding	LOC100361543	IPI	UniProtKB:Q9JHS3	Rat	PMID:19177150|RGD:8553879
Molecular Function	GO:0005515	protein binding	Lamtor1	IPI	UniProtKB:O88653	Rat	PMID:19177150|RGD:8553879
Molecular Function	GO:0005515	protein binding	Lamtor1	IPI	UniProtKB:Q5U204	Rat	PMID:19177150|RGD:8553879
Molecular Function	GO:0005515	protein binding	Lamtor1	IPI	UniProtKB:Q9JHS3	Rat	PMID:19177150|RGD:8553879
Cellular Component	GO:0070062	extracellular exosome	LAMTOR1	HDA		Human	PMID:19056867
Cellular Component	GO:0031902	late endosome membrane	LOC100361543	IDA		Rat	PMID:19177150|RGD:8553879
Cellular Component	GO:0031902	late endosome membrane	Lamtor1	IDA		Rat	PMID:19177150|RGD:8553879
Cellular Component	GO:0005764	lysosome	LAMTOR1	IDA		Human	PMID:20544018
Cellular Component	GO:0045121	membrane raft	LOC100361543	IDA		Rat	PMID:19177150|RGD:8553879
Cellular Component	GO:0045121	membrane raft	Lamtor1	IDA		Rat	PMID:19177150|RGD:8553879
Cellular Component	GO:0071986	Ragulator complex	LAMTOR1	IPI		Human	PMID:28935770
Cellular Component	GO:0071986	Ragulator complex	LAMTOR1	IDA		Human	PMID:20381137
Biological Process	GO:0071230	cellular response to amino acid stimulus	LAMTOR1	IMP		Human	PMID:20381137
Biological Process	GO:0071230	cellular response to amino acid stimulus	LAMTOR1	IDA		Human	PMID:22980980
Biological Process	GO:0042632	cholesterol homeostasis	LAMTOR1	IMP		Human	PMID:20544018
Biological Process	GO:0016197	endosomal transport	Lamtor1	IMP		Mouse	MGI:MGI:4887551|PMID:19177150
Biological Process	GO:0007032	endosome organization	Lamtor1	IMP		Mouse	MGI:MGI:4887551|PMID:19177150
Biological Process	GO:0032418	lysosome localization	Lamtor1	IMP		Mouse	MGI:MGI:4887551|PMID:19177150
Biological Process	GO:0007040	lysosome organization	Lamtor1	IMP		Mouse	MGI:MGI:4887551|PMID:19177150
Biological Process	GO:0043410	positive regulation of MAPK cascade	Lamtor1	IMP		Mouse	MGI:MGI:4887551|PMID:19177150
Biological Process	GO:0032008	positive regulation of TOR signaling	LAMTOR1	IMP		Human	PMID:20381137
Biological Process	GO:0008104	protein localization	LAMTOR1	IMP		Human	PMID:20381137
Biological Process	GO:0008104	protein localization	Lamtor1	IMP		Mouse	MGI:MGI:4887551|PMID:19177150
Biological Process	GO:0001558	regulation of cell growth	LAMTOR1	IMP		Human	PMID:20381137
Biological Process	GO:0010874	regulation of cholesterol efflux	LAMTOR1	IMP		Human	PMID:20544018
Biological Process	GO:0060620	regulation of cholesterol import	LAMTOR1	IMP		Human	PMID:20544018
Biological Process	GO:0001919	regulation of receptor recycling	Lamtor1	IMP		Mouse	MGI:MGI:4887551|PMID:19177150

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern