Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LAMTOR2
  • Mouse genes Lamtor2
  • Rat genes Lamtor2
  • Zfish genes lamtor2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lamtor2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	LAMTOR2	IDA		Human	PMID:22980980
Molecular Function	GO:0060090	molecular adaptor activity	LAMTOR2	IDA		Human	PMID:22980980
Molecular Function	GO:0005515	protein binding	LAMTOR2	IPI	UniProtKB:Q6IAA8	Human	PMID:20381137
Molecular Function	GO:0005515	protein binding	LAMTOR2	IPI	UniProtKB:Q9UHA4	Human	PMID:20381137
Molecular Function	GO:0005515	protein binding	LAMTOR2	IPI	UniProtKB:Q9UHA4	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	LAMTOR2	IPI	UniProtKB:Q9UHA4	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	LAMTOR2	IPI	UniProtKB:Q6IAA8	Human	PMID:22980980
Molecular Function	GO:0005515	protein binding	LAMTOR2	IPI	UniProtKB:Q9UHA4	Human	PMID:22980980
Molecular Function	GO:0005515	protein binding	LAMTOR2	IPI	UniProtKB:Q9UHA4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LAMTOR2	IPI	UniProtKB:Q6IAA8	Human	PMID:25561175
Molecular Function	GO:0005515	protein binding	LAMTOR2	IPI	UniProtKB:Q8NBW4	Human	PMID:25561175
Molecular Function	GO:0005515	protein binding	LAMTOR2	IPI	UniProtKB:Q9UHA4	Human	PMID:25561175
Molecular Function	GO:0005515	protein binding	LAMTOR2	IPI	UniProtKB:Q6IAA8	Human	PMID:25567906
Molecular Function	GO:0005515	protein binding	LAMTOR2	IPI	UniProtKB:Q8NBW4	Human	PMID:25567906
Molecular Function	GO:0005515	protein binding	LAMTOR2	IPI	UniProtKB:Q96GS4	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	LAMTOR2	IPI	UniProtKB:Q6IAA8	Human	PMID:29123114
Molecular Function	GO:0005515	protein binding	LAMTOR2	IPI	UniProtKB:Q96GS4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LAMTOR2	IPI	UniProtKB:Q9UHA4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Lamtor2	IPI	UniProtKB:Q9CQ22	Mouse	MGI:MGI:4887551|PMID:19177150
Molecular Function	GO:0005515	protein binding	Lamtor2	IPI	UniProtKB:O88653	Mouse	MGI:MGI:3693387|PMID:15263099
Molecular Function	GO:0005515	protein binding	Lamtor2	IPI	UniProtKB:Q6P791	Mouse	MGI:MGI:4887551|PMID:19177150
Cellular Component	GO:0005770	late endosome	Lamtor2	IDA		Mouse	MGI:MGI:4887551|PMID:19177150
Cellular Component	GO:0005770	late endosome	Lamtor2	IDA		Mouse	PMID:15263099
Cellular Component	GO:0005770	late endosome	Lamtor2	IDA		Mouse	PMID:24841562
Cellular Component	GO:0005765	lysosomal membrane	LAMTOR2	HDA		Human	PMID:17897319
Cellular Component	GO:0071986	Ragulator complex	LAMTOR2	IPI		Human	PMID:28935770
Cellular Component	GO:0071986	Ragulator complex	LAMTOR2	IDA		Human	PMID:20381137
Biological Process	GO:0071230	cellular response to amino acid stimulus	LAMTOR2	IMP		Human	PMID:20381137
Biological Process	GO:0071230	cellular response to amino acid stimulus	LAMTOR2	IDA		Human	PMID:22980980
Biological Process	GO:0010761	fibroblast migration	Lamtor2	IMP	MGI:MGI:3701832	Mouse	PMID:24841562
Biological Process	GO:0010761	fibroblast migration	Lamtor2	IDA		Mouse	PMID:24841562
Biological Process	GO:0010761	fibroblast migration	Lamtor2	IGI	MGI:MGI:1352757	Mouse	PMID:24841562
Biological Process	GO:0043410	positive regulation of MAPK cascade	Lamtor2	IDA		Mouse	PMID:15263099
Biological Process	GO:0032008	positive regulation of TOR signaling	LAMTOR2	IMP		Human	PMID:20381137
Biological Process	GO:0008104	protein localization	LAMTOR2	IMP		Human	PMID:20381137
Biological Process	GO:1902414	protein localization to cell junction	Lamtor2	IMP	UniProtKB:Q9Y2Q5	Mouse	PMID:24841562
Biological Process	GO:0001558	regulation of cell growth	LAMTOR2	IMP		Human	PMID:20381137
Biological Process	GO:0150116	regulation of cell-substrate junction organization	LAMTOR2	IMP		Human	PMID:24841562
Biological Process	GO:0150116	regulation of cell-substrate junction organization	Lamtor2	IDA		Mouse	PMID:24841562
Biological Process	GO:0150116	regulation of cell-substrate junction organization	Lamtor2	IMP	MGI:MGI:3701832	Mouse	PMID:24841562

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern