Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LAMTOR5
  • Mouse genes Lamtor5
  • Rat genes Lamtor5
  • Zfish genes lamtor5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lamtor5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	LAMTOR5	IDA		Human	PMID:22980980
Molecular Function	GO:0060090	molecular adaptor activity	LAMTOR5	IDA		Human	PMID:22980980
Molecular Function	GO:0005515	protein binding	LAMTOR5	IPI	UniProtKB:O15392-1	Human	PMID:12773388
Molecular Function	GO:0005515	protein binding	LAMTOR5	IPI	UniProtKB:Q14765	Human	PMID:22740693
Molecular Function	GO:0005515	protein binding	LAMTOR5	IPI	UniProtKB:Q0VGL1	Human	PMID:23414517
Molecular Function	GO:0005515	protein binding	LAMTOR5	IPI	UniProtKB:Q9WMX2:PRO_0000037547	Human	PMID:24169621
Molecular Function	GO:0005515	protein binding	LAMTOR5	IPI	UniProtKB:Q0VGL1	Human	PMID:25561175
Molecular Function	GO:0005515	protein binding	LAMTOR5	IPI	UniProtKB:Q8NBW4	Human	PMID:25561175
Molecular Function	GO:0005515	protein binding	LAMTOR5	IPI	UniProtKB:Q8NBW4	Human	PMID:25567906
Molecular Function	GO:0005515	protein binding	LAMTOR5	IPI	UniProtKB:Q0VGL1	Human	PMID:29123114
Cellular Component	GO:0005829	cytosol	LAMTOR5	IDA		Human	PMID:12773388
Cellular Component	GO:0005764	lysosome	LAMTOR5	IDA		Human	PMID:22980980
Cellular Component	GO:0032991	protein-containing complex	LAMTOR5	IDA		Human	PMID:12773388
Cellular Component	GO:0071986	Ragulator complex	LAMTOR5	IPI		Human	PMID:28935770
Cellular Component	GO:0071986	Ragulator complex	LAMTOR5	IDA		Human	PMID:22980980
Biological Process	GO:0071230	cellular response to amino acid stimulus	LAMTOR5	IDA		Human	PMID:22980980
Biological Process	GO:0071230	cellular response to amino acid stimulus	LAMTOR5	IMP		Human	PMID:22980980
Biological Process	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	LAMTOR5	IDA		Human	PMID:12773388
Biological Process	GO:0010628	positive regulation of gene expression	LAMTOR5	IGI	UniProtKB:Q04206	Human	PMID:21343296
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	LAMTOR5	IDA		Human	PMID:21343296
Biological Process	GO:0032757	positive regulation of interleukin-8 production	LAMTOR5	IGI	UniProtKB:Q04206	Human	PMID:21343296
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	LAMTOR5	IGI	UniProtKB:Q04206	Human	PMID:21343296
Biological Process	GO:1900182	positive regulation of protein localization to nucleus	LAMTOR5	IDA		Human	PMID:21343296
Biological Process	GO:1905636	positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding	LAMTOR5	IDA		Human	PMID:21343296
Biological Process	GO:0032008	positive regulation of TOR signaling	LAMTOR5	IMP		Human	PMID:22980980
Biological Process	GO:0061462	protein localization to lysosome	LAMTOR5	IMP		Human	PMID:22980980
Biological Process	GO:0008361	regulation of cell size	LAMTOR5	IMP		Human	PMID:22980980

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern