Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LAT
  • Mouse genes Lat
  • Rat genes Lat
  • Zfish genes lat
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lat

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	LAT	IPI	UniProtKB:P19174	Human	PMID:10811803
Molecular Function	GO:0005515	protein binding	LAT	IPI	UniProtKB:P27986	Human	PMID:10811803
Molecular Function	GO:0005515	protein binding	LAT	IPI	UniProtKB:P62993	Human	PMID:10811803
Molecular Function	GO:0005515	protein binding	LAT	IPI	UniProtKB:P15498	Human	PMID:12186560
Molecular Function	GO:0005515	protein binding	LAT	IPI	UniProtKB:P43403	Human	PMID:12646565
Molecular Function	GO:0005515	protein binding	LAT	IPI	UniProtKB:P18031	Human	PMID:12857726
Molecular Function	GO:0005515	protein binding	LAT	IPI	UniProtKB:P19174	Human	PMID:14722116
Molecular Function	GO:0005515	protein binding	LAT	IPI	UniProtKB:Q60631	Human	PMID:14722116
Molecular Function	GO:0005515	protein binding	LAT	IPI	UniProtKB:P06239	Human	PMID:16938345
Molecular Function	GO:0005515	protein binding	LAT	IPI	UniProtKB:P19174	Human	PMID:16938345
Molecular Function	GO:0005515	protein binding	LAT	IPI	UniProtKB:P62993	Human	PMID:16938345
Molecular Function	GO:0005515	protein binding	LAT	IPI	UniProtKB:P19174	Human	PMID:24642916
Molecular Function	GO:0005515	protein binding	LAT	IPI	UniProtKB:P00533	Human	PMID:24658140
Molecular Function	GO:0005515	protein binding	LAT	IPI	UniProtKB:O43765	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LAT	IPI	UniProtKB:P00533	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	LAT	IPI	UniProtKB:P19174	Human	PMID:9489702
Molecular Function	GO:0005515	protein binding	LAT	IPI	UniProtKB:P62993	Human	PMID:9489702
Molecular Function	GO:0005515	protein binding	Lat	IPI	UniProtKB:Q60631|UniProtKB:Q60787|UniProtKB:Q62077	Mouse	MGI:MGI:5568870|PMID:24584089
Molecular Function	GO:0005515	protein binding	Lat	IPI	UniProtKB:Q60631|UniProtKB:Q62077	Mouse	MGI:MGI:5432321|PMID:22561606
Molecular Function	GO:0005515	protein binding	Lat	IPI	UniProtKB:Q60631|UniProtKB:Q60787|UniProtKB:Q62077	Mouse	MGI:MGI:5003385|PMID:21487392
Molecular Function	GO:0005515	protein binding	Lat	IPI	PR:Q8BGW0	Mouse	PMID:22732588
Molecular Function	GO:0005515	protein binding	Lat	IPI	PR:Q91YX0	Mouse	PMID:22732588
Molecular Function	GO:0019901	protein kinase binding	LAT	IPI	UniProtKB:Q08881	Human	PMID:12186560
Molecular Function	GO:0030159	signaling receptor complex adaptor activity	LAT	IDA		Human	PMID:9489702
Cellular Component	GO:0005911	cell-cell junction	Lat	IDA		Mouse	PMID:23793062
Cellular Component	GO:0008180	COP9 signalosome	Lat	IDA		Mouse	MGI:MGI:5432321|PMID:22561606
Cellular Component	GO:0005794	Golgi apparatus	LAT	IDA		Human	GO_REF:0000052
Cellular Component	GO:0001772	immunological synapse	LAT	IDA		Human	PMID:12646565
Cellular Component	GO:0001772	immunological synapse	Lat	IDA		Mouse	PMID:14635057
Cellular Component	GO:0016020	membrane	LAT	IDA		Human	PMID:12646565
Cellular Component	GO:0005886	plasma membrane	LAT	IDA		Human	PMID:9729044
Cellular Component	GO:0005886	plasma membrane	LAT	IDA		Human	GO_REF:0000052
Biological Process	GO:0019722	calcium-mediated signaling	LAT	IMP		Human	PMID:12646565
Biological Process	GO:0010467	gene expression	Lat	IMP		Mouse	PMID:16002666
Biological Process	GO:0048872	homeostasis of number of cells	Lat	IMP	MGI:MGI:5547536	Mouse	PMID:23793062
Biological Process	GO:0006955	immune response	LAT	IDA		Human	PMID:15100278
Biological Process	GO:0006954	inflammatory response	Lat	IMP		Mouse	PMID:16002666
Biological Process	GO:0007229	integrin-mediated signaling pathway	LAT	IDA		Human	PMID:15100278
Biological Process	GO:0035556	intracellular signal transduction	LAT	IDA		Human	PMID:12646565
Biological Process	GO:0002260	lymphocyte homeostasis	Lat	IMP	MGI:MGI:5547536	Mouse	PMID:23776175
Biological Process	GO:0045860	positive regulation of protein kinase activity	LAT	IEP		Human	PMID:14624253
Biological Process	GO:0007265	Ras protein signal transduction	LAT	IMP		Human	PMID:12646565
Biological Process	GO:0050863	regulation of T cell activation	LAT	IMP		Human	PMID:12646565
Biological Process	GO:0050852	T cell receptor signaling pathway	LAT	IDA		Human	PMID:25907557

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern