Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LBH
  • Mouse genes Lbh
  • Rat genes Lbh
  • Zfish genes lbh
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lbh

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	LBH	IPI	UniProtKB:P02511	Human	PMID:20587334
Cellular Component	GO:0005737	cytoplasm	LBH	IDA		Human	PMID:17390236
Cellular Component	GO:0005634	nucleus	LBH	IDA		Human	PMID:17390236
Cellular Component	GO:0005634	nucleus	LBH	IDA		Human	PMID:20587334
Cellular Component	GO:0005634	nucleus	Lbh	IDA		Mouse	MGI:MGI:5634223|PMID:25655704
Cellular Component	GO:0005634	nucleus	Lbh	IDA		Mouse	PMID:11336496
Cellular Component	GO:0032991	protein-containing complex	LBH	IDA		Human	PMID:20587334
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	lbh	IMP	ZFIN:ZDB-MRPHLNO-150323-3	Zfish	PMID:25234704
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	lbh	IMP	ZFIN:ZDB-MRPHLNO-150323-2	Zfish	PMID:25234704
Biological Process	GO:0030879	mammary gland development	Lbh	IMP		Mouse	MGI:MGI:5634223|PMID:25655704
Biological Process	GO:0060644	mammary gland epithelial cell differentiation	Lbh	IMP		Mouse	MGI:MGI:5634223|PMID:25655704
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	LBH	IDA		Human	PMID:20587334
Biological Process	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway	Lbh	IMP		Mouse	MGI:MGI:5634223|PMID:25655704
Biological Process	GO:2000737	negative regulation of stem cell differentiation	Lbh	IMP		Mouse	MGI:MGI:5634223|PMID:25655704
Biological Process	GO:0001755	neural crest cell migration	lbh	IMP	ZFIN:ZDB-MRPHLNO-150323-3	Zfish	PMID:25234704
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	LBH	IDA		Human	PMID:17390236
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Lbh	IDA		Mouse	PMID:11336496
Biological Process	GO:2000103	positive regulation of mammary stem cell proliferation	Lbh	IMP		Mouse	MGI:MGI:5634223|PMID:25655704
Biological Process	GO:1904677	positive regulation of somatic stem cell division	Lbh	IMP		Mouse	MGI:MGI:5634223|PMID:25655704
Biological Process	GO:1904674	positive regulation of somatic stem cell population maintenance	Lbh	IMP		Mouse	MGI:MGI:5634223|PMID:25655704
Biological Process	GO:0010468	regulation of gene expression	Lbh	IMP		Mouse	MGI:MGI:5634223|PMID:25655704
Biological Process	GO:0043408	regulation of MAPK cascade	LBH	IMP		Human	PMID:17390236

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern