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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Lbp

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lbp
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0015026coreceptor activityLBPIPIUniProtKB:Q9R3N6HumanPMID:15294986
Molecular FunctionGO:0071723lipopeptide bindingLBPIDAHumanPMID:15294986
Molecular FunctionGO:0001530lipopolysaccharide bindingLBPIDAHumanPMID:12594207
Molecular FunctionGO:0001530lipopolysaccharide bindingLBPIMPHumanPMID:24120359
Molecular FunctionGO:0001530lipopolysaccharide bindingLbpIDAMousePMID:11079463
Molecular FunctionGO:0001530lipopolysaccharide bindingLbpIDARatPMID:22580761|RGD:9685189
Molecular FunctionGO:0070891lipoteichoic acid bindingLBPIDAHumanPMID:12594207
Molecular FunctionGO:0005515protein bindingLBPIPIUniProtKB:Q13162HumanPMID:21988832
Molecular FunctionGO:0005515protein bindingLBPIPIUniProtKB:P23560-2HumanPMID:32814053
Molecular FunctionGO:0005102signaling receptor bindingLbpIDAMouseMGI:MGI:1097829|PMID:9338787
Cellular ComponentGO:0009986cell surfaceLBPIDAHumanPMID:11528597
Cellular ComponentGO:0009986cell surfaceLbpIDAMouseMGI:MGI:3807766|PMID:12932360
Cellular ComponentGO:0070062extracellular exosomeLBPHDAHumanPMID:19056867
Cellular ComponentGO:0070062extracellular exosomeLBPHDAHumanPMID:23533145
Cellular ComponentGO:0005615extracellular spaceLBPIDAHumanPMID:11528597
Cellular ComponentGO:0005615extracellular spaceLBPIDAHumanPMID:2402637
Cellular ComponentGO:0005615extracellular spaceLBPIDAHumanPMID:24120359
Cellular ComponentGO:0005615extracellular spaceLbpIDAMouseMGI:MGI:1097829|PMID:9338787
Cellular ComponentGO:0005615extracellular spaceLbpIDAMousePMID:12055258
Cellular ComponentGO:0005615extracellular spaceLbpIDARatPMID:22580761|RGD:9685189
Biological ProcessGO:0006953acute-phase responseLBPIEPHumanPMID:12932360
Biological ProcessGO:0006953acute-phase responseLbpIMPMouseMGI:MGI:3807766|PMID:12932360
Biological ProcessGO:0002752cell surface pattern recognition receptor signaling pathwayLBPIDAHumanPMID:15294986
Biological ProcessGO:0071222cellular response to lipopolysaccharideLBPIDAHumanPMID:12594207
Biological ProcessGO:0071222cellular response to lipopolysaccharideLBPIMPHumanPMID:24120359
Biological ProcessGO:0071222cellular response to lipopolysaccharideLbpIMPMouseMGI:MGI:5645195|PMID:24380872
Biological ProcessGO:0071223cellular response to lipoteichoic acidLBPIDAHumanPMID:12594207
Biological ProcessGO:0050829defense response to Gram-negative bacteriumLBPIDAHumanPMID:11528597
Biological ProcessGO:0050829defense response to Gram-negative bacteriumLbpIMPMouseMGI:MGI:1097829|PMID:9338787
Biological ProcessGO:0050829defense response to Gram-negative bacteriumLbpIMPMGI:MGI:1857975MousePMID:12055258
Biological ProcessGO:0050830defense response to Gram-positive bacteriumLBPIDAHumanPMID:12932360
Biological ProcessGO:0050830defense response to Gram-positive bacteriumLbpIMPMouseMGI:MGI:3807766|PMID:12932360
Biological ProcessGO:0032490detection of molecule of bacterial originLBPIDAHumanPMID:11528597
Biological ProcessGO:0045087innate immune responseLbpIMPMouseMGI:MGI:3807766|PMID:12932360
Biological ProcessGO:0002232leukocyte chemotaxis involved in inflammatory responseLbpIMPMGI:MGI:1857975MousePMID:12055258
Biological ProcessGO:0015920lipopolysaccharide transportLBPIDAHumanPMID:8985160
Biological ProcessGO:0031663lipopolysaccharide-mediated signaling pathwayLBPIDAHumanPMID:11739189
Biological ProcessGO:0031663lipopolysaccharide-mediated signaling pathwayLBPIDAHumanPMID:8409400
Biological ProcessGO:0001889liver developmentLbpIEPRatPMID:20978830|RGD:9685195
Biological ProcessGO:0002281macrophage activation involved in immune responseLBPIMPHumanPMID:24120359
Biological ProcessGO:0002281macrophage activation involved in immune responseLbpIDAMouseMGI:MGI:3807766|PMID:12932360
Biological ProcessGO:0032720negative regulation of tumor necrosis factor productionLBPIDAHumanPMID:11739189
Biological ProcessGO:0030593neutrophil chemotaxisLbpIMPMGI:MGI:1857975MousePMID:12055258
Biological ProcessGO:0032722positive regulation of chemokine productionLbpIMPMGI:MGI:1857975MousePMID:12055258
Biological ProcessGO:0032755positive regulation of interleukin-6 productionLBPIDAHumanPMID:8409400
Biological ProcessGO:0032757positive regulation of interleukin-8 productionLBPIDAHumanPMID:8409400
Biological ProcessGO:0043032positive regulation of macrophage activationLBPIDAHumanPMID:8409400
Biological ProcessGO:0043032positive regulation of macrophage activationLbpIDARatPMID:10733550|RGD:9685188
Biological ProcessGO:0090023positive regulation of neutrophil chemotaxisLbpIMPMGI:MGI:1857975MousePMID:12055258
Biological ProcessGO:0060100positive regulation of phagocytosis, engulfmentLbpIDARatPMID:11104656|RGD:9685187
Biological ProcessGO:0060265positive regulation of respiratory burst involved in inflammatory responseLbpIMPMouseMGI:MGI:1097829|PMID:9338787
Biological ProcessGO:0034145positive regulation of toll-like receptor 4 signaling pathwayLBPIDAHumanPMID:11528597
Biological ProcessGO:0032760positive regulation of tumor necrosis factor productionLBPIDAHumanPMID:12594207
Biological ProcessGO:0032760positive regulation of tumor necrosis factor productionLBPIMPHumanPMID:24120359
Biological ProcessGO:0032760positive regulation of tumor necrosis factor productionLBPIDAHumanPMID:8409400
Biological ProcessGO:0032760positive regulation of tumor necrosis factor productionLbpIDAMouseMGI:MGI:3807766|PMID:12932360
Biological ProcessGO:0032760positive regulation of tumor necrosis factor productionLbpIMPMouseMGI:MGI:1097829|PMID:9338787
Biological ProcessGO:0032760positive regulation of tumor necrosis factor productionLbpIMPMouseMGI:MGI:5645195|PMID:24380872
Biological ProcessGO:0032760positive regulation of tumor necrosis factor productionLbpIMPMGI:MGI:1857975MousePMID:12055258
Biological ProcessGO:0090559regulation of membrane permeabilityLbpIMPRatPMID:17446308|RGD:9685199
Biological ProcessGO:0032496response to lipopolysaccharideLBPIDAHumanPMID:11739189
Biological ProcessGO:0032496response to lipopolysaccharideLBPIDAHumanPMID:8409400
Biological ProcessGO:0032496response to lipopolysaccharideLbpIMPMouseMGI:MGI:1097829|PMID:9338787
Biological ProcessGO:0032496response to lipopolysaccharideLbpIMPMGI:MGI:1857975MousePMID:12055258
Biological ProcessGO:0032640tumor necrosis factor productionLbpIMPMGI:MGI:1857975MousePMID:12055258

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory