Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LBR
  • Mouse genes Lbr
  • Rat genes Lbr
  • Zfish genes lbr
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lbr

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070087	chromo shadow domain binding	LBR	IPI	UniProtKB:P45973	Human	PMID:15882967
Molecular Function	GO:0050613	delta14-sterol reductase activity	LBR	IMP		Human	PMID:12618959
Molecular Function	GO:0050613	delta14-sterol reductase activity	LBR	IDA		Human	PMID:16784888
Molecular Function	GO:0050613	delta14-sterol reductase activity	LBR	IMP		Human	PMID:21327084
Molecular Function	GO:0050613	delta14-sterol reductase activity	LBR	IMP		Human	PMID:27336722
Molecular Function	GO:0050613	delta14-sterol reductase activity	LBR	IDA		Human	PMID:9630650
Molecular Function	GO:0050613	delta14-sterol reductase activity	Lbr	IMP		Mouse	MGI:MGI:3822946|PMID:18785926
Molecular Function	GO:0050613	delta14-sterol reductase activity	Lbr	IMP		Mouse	MGI:MGI:5308142|PMID:22140257
Molecular Function	GO:0070402	NADPH binding	LBR	IMP		Human	PMID:27336722
Molecular Function	GO:0008139	nuclear localization sequence binding	Lbr	IPI	UniProtKB:P03070|UniProtKB:P05221	Rat	PMID:8486604|RGD:9588618
Molecular Function	GO:0005515	protein binding	LBR	IPI	UniProtKB:Q7Z7G1	Human	PMID:26009488
Molecular Function	GO:0005515	protein binding	LBR	IPI	UniProtKB:P60033	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LBR	IPI	UniProtKB:Q9BVK8	Human	PMID:32694168
Molecular Function	GO:0005515	protein binding	LBR	IPI	UniProtKB:P45973	Human	PMID:8663349
Molecular Function	GO:0005515	protein binding	LBR	IPI	UniProtKB:Q13185	Human	PMID:8663349
Molecular Function	GO:0005515	protein binding	Lbr	IPI	UniProtKB:Q9QZE2	Mouse	MGI:MGI:6355741|PMID:26009488
Molecular Function	GO:0005515	protein binding	Lbr	IPI	UniProtKB:P05221	Rat	PMID:9192729|RGD:633039
Molecular Function	GO:0051087	protein-folding chaperone binding	Lbr	IPI	UniProtKB:P05221	Rat	PMID:8486604|RGD:9588618
Molecular Function	GO:0003723	RNA binding	LBR	HDA		Human	PMID:22681889
Cellular Component	GO:0005737	cytoplasm	LBR	IDA		Human	PMID:21327084
Cellular Component	GO:0005737	cytoplasm	Lbr	IDA		Rat	PMID:8598227|RGD:9588616
Cellular Component	GO:0005789	endoplasmic reticulum membrane	LBR	IDA		Human	PMID:21327084
Cellular Component	GO:0016020	membrane	LBR	IDA		Human	PMID:15698635
Cellular Component	GO:0016020	membrane	LBR	HDA		Human	PMID:19946888
Cellular Component	GO:0005635	nuclear envelope	Lbr	IDA		Mouse	PMID:20457914
Cellular Component	GO:0005635	nuclear envelope	Lbr	IDA		Rat	PMID:8598227|RGD:9588616
Cellular Component	GO:0005637	nuclear inner membrane	LBR	IDA		Human	PMID:32694168
Cellular Component	GO:0005637	nuclear inner membrane	lbr	IDA		Zfish	PMID:16759737
Cellular Component	GO:0031965	nuclear membrane	LBR	IDA		Human	GO_REF:0000052
Cellular Component	GO:0031965	nuclear membrane	Lbr	IDA		Mouse	MGI:MGI:3822946|PMID:18785926
Cellular Component	GO:0005643	nuclear pore	Lbr	IDA		Rat	PMID:12438562|RGD:1600216
Cellular Component	GO:0005634	nucleus	LBR	IDA		Human	PMID:21327084
Biological Process	GO:0042074	cell migration involved in gastrulation	lbr	IMP	ZFIN:ZDB-MRPHLNO-060822-8	Zfish	PMID:16759737
Biological Process	GO:0006695	cholesterol biosynthetic process	LBR	IDA		Human	PMID:16784888
Biological Process	GO:0006695	cholesterol biosynthetic process	LBR	IMP		Human	PMID:27336722
Biological Process	GO:0006695	cholesterol biosynthetic process	Lbr	IDA		Mouse	MGI:MGI:3822946|PMID:18785926
Biological Process	GO:0006695	cholesterol biosynthetic process	Lbr	IMP		Mouse	MGI:MGI:5308142|PMID:22140257
Biological Process	GO:0000278	mitotic cell cycle	Lbr	IEP		Rat	PMID:8598227|RGD:9588616
Biological Process	GO:0030223	neutrophil differentiation	Lbr	IMP		Mouse	MGI:MGI:5308142|PMID:22140257

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern