Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LBX1
  • Mouse genes Lbx1
  • Rat genes Lbx1
  • Zfish genes lbx1a,lbx1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lbx1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Lbx1	IDA		Mouse	PMID:15528197
Molecular Function	GO:0005515	protein binding	LBX1	IPI	UniProtKB:A6H8Z2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LBX1	IPI	UniProtKB:O43189	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LBX1	IPI	UniProtKB:O95967	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LBX1	IPI	UniProtKB:P0CB47	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LBX1	IPI	UniProtKB:P17661	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LBX1	IPI	UniProtKB:P33176	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LBX1	IPI	UniProtKB:P46940	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LBX1	IPI	UniProtKB:P63241	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LBX1	IPI	UniProtKB:Q2TAL8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LBX1	IPI	UniProtKB:Q5QJ74	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LBX1	IPI	UniProtKB:Q63ZY3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LBX1	IPI	UniProtKB:Q6L8G9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LBX1	IPI	UniProtKB:Q6P088	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LBX1	IPI	UniProtKB:Q8IZU0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LBX1	IPI	UniProtKB:Q8N6L7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LBX1	IPI	UniProtKB:Q8N8X9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LBX1	IPI	UniProtKB:Q8WWY3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LBX1	IPI	UniProtKB:Q96PN8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LBX1	IPI	UniProtKB:Q9BVG8-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LBX1	IPI	UniProtKB:Q9BYP7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LBX1	IPI	UniProtKB:Q9BYQ4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LBX1	IPI	UniProtKB:Q9NZN9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Lbx1	IPI	PR:Q62440	Mouse	PMID:15528197
Molecular Function	GO:0005515	protein binding	Lbx1	IPI	PR:Q8BX46	Mouse	PMID:15528197
Cellular Component	GO:0005667	transcription regulator complex	Lbx1	IDA		Mouse	PMID:15528197
Biological Process	GO:0008283	cell population proliferation	Lbx1	IMP	MGI:MGI:2386948	Mouse	PMID:12522123
Biological Process	GO:0060026	convergent extension	lbx1b	IMP		Zfish	PMID:26820155
Biological Process	GO:0060026	convergent extension	lbx1b	IGI	GenBank:NM_001313941	Zfish	PMID:26820155
Biological Process	GO:0060026	convergent extension	lbx1b	IGI	ZFIN:ZDB-GENE-980526-87	Zfish	PMID:26820155
Biological Process	GO:1905962	glutamatergic neuron differentiation	Lbx1	IMP	MGI:MGI:2182635	Mouse	PMID:16234809
Biological Process	GO:0001947	heart looping	Lbx1	IMP	MGI:MGI:2386948	Mouse	PMID:12522123
Biological Process	GO:0042692	muscle cell differentiation	lbx1b	IMP		Zfish	PMID:19216761|ZFIN:ZDB-PUB-090217-39
Biological Process	GO:0008285	negative regulation of cell population proliferation	Lbx1	IMP	MGI:MGI:2386948	Mouse	PMID:12522123
Biological Process	GO:0120007	negative regulation of glutamatergic neuron differentiation	Lbx1	IMP	MGI:MGI:2182635	Mouse	PMID:16234809
Biological Process	GO:0048663	neuron fate commitment	Lbx1	IMP	MGI:MGI:1352738	Mouse	PMID:12062039
Biological Process	GO:0048664	neuron fate determination	Lbx1	IGI	MGI:MGI:1351209	Mouse	PMID:16234809
Biological Process	GO:0048664	neuron fate determination	Lbx1	IMP	MGI:MGI:2182635	Mouse	PMID:16234809
Biological Process	GO:0006355	regulation of DNA-templated transcription	Lbx1	IDA		Mouse	PMID:15528197
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Lbx1	IMP	MGI:MGI:2182635	Mouse	PMID:12062038
Biological Process	GO:0030111	regulation of Wnt signaling pathway	lbx1b	IGI		Zfish	PMID:26820155
Biological Process	GO:0021522	spinal cord motor neuron differentiation	Lbx1	IGI	MGI:MGI:2149955	Mouse	PMID:15769945

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern