Comparative GO Graph (mouse, human, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LCOR
  • Mouse genes Lcor
  • Rat genes
  • Zfish genes lcor
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lcor

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Lcor	IDA		Mouse	PMID:17392792
Molecular Function	GO:0042826	histone deacetylase binding	LCOR	IPI	UniProtKB:O15379	Human	PMID:12535528
Molecular Function	GO:0042826	histone deacetylase binding	LCOR	IPI	UniProtKB:Q9UBN7	Human	PMID:12535528
Molecular Function	GO:1990226	histone methyltransferase binding	LCOR	IPI	UniProtKB:Q15910	Human	PMID:29628311
Molecular Function	GO:1990226	histone methyltransferase binding	LCOR	IPI	UniProtKB:Q96KQ7	Human	PMID:29628311
Molecular Function	GO:1990226	histone methyltransferase binding	LCOR	IPI	UniProtKB:Q9H9B1	Human	PMID:29628311
Molecular Function	GO:0030331	nuclear estrogen receptor binding	LCOR	IPI	UniProtKB:P03372	Human	PMID:12535528
Molecular Function	GO:0005515	protein binding	LCOR	IPI	UniProtKB:Q13363	Human	PMID:20211142
Molecular Function	GO:0005515	protein binding	LCOR	IPI	UniProtKB:A2ABF9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LCOR	IPI	UniProtKB:P56545	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LCOR	IPI	UniProtKB:P56545-3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LCOR	IPI	UniProtKB:Q08379	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LCOR	IPI	UniProtKB:Q13077	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LCOR	IPI	UniProtKB:P56545	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	LCOR	IPI	UniProtKB:Q13363	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	LCOR	IPI	UniProtKB:Q13363	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	LCOR	IPI	UniProtKB:O43189	Human	PMID:29628311
Molecular Function	GO:0005515	protein binding	LCOR	IPI	UniProtKB:O75530	Human	PMID:29628311
Molecular Function	GO:0005515	protein binding	LCOR	IPI	UniProtKB:O95785	Human	PMID:29628311
Molecular Function	GO:0005515	protein binding	LCOR	IPI	UniProtKB:Q15022	Human	PMID:29628311
Molecular Function	GO:0005515	protein binding	LCOR	IPI	UniProtKB:Q9H582	Human	PMID:29628311
Molecular Function	GO:0005515	protein binding	LCOR	IPI	UniProtKB:Q9Y483	Human	PMID:29628311
Molecular Function	GO:0005515	protein binding	LCOR	IPI	UniProtKB:Q13363	Human	PMID:31041561
Molecular Function	GO:0005515	protein binding	LCOR	IPI	UniProtKB:P56545	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	LCOR	IPI	UniProtKB:Q13363	Human	PMID:35016035
Molecular Function	GO:0005515	protein binding	Lcor	IPI	PR:Q6ZQ88	Mouse	PMID:17392792
Molecular Function	GO:0003714	transcription corepressor activity	LCOR	IDA		Human	PMID:12535528
Molecular Function	GO:0001222	transcription corepressor binding	LCOR	IPI	UniProtKB:P56545	Human	PMID:29628311
Molecular Function	GO:0001222	transcription corepressor binding	LCOR	IPI	UniProtKB:Q13363	Human	PMID:29628311
Molecular Function	GO:1990381	ubiquitin-specific protease binding	LCOR	IPI	UniProtKB:P51784	Human	PMID:29628311
Molecular Function	GO:1990381	ubiquitin-specific protease binding	LCOR	IPI	UniProtKB:Q9UPT9	Human	PMID:29628311
Cellular Component	GO:0005654	nucleoplasm	LCOR	IDA		Human	GO_REF:0000052
Biological Process	GO:0071392	cellular response to estradiol stimulus	LCOR	IDA		Human	PMID:12535528
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	LCOR	IDA		Human	PMID:12535528
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Lcor	IDA		Mouse	PMID:17392792
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Lcor	IMP		Mouse	PMID:17392792
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Lcor	IDA		Mouse	PMID:12560079
Biological Process	GO:0006366	transcription by RNA polymerase II	Lcor	IDA		Mouse	PMID:12560079
Biological Process	GO:0045815	transcription initiation-coupled chromatin remodeling	Lcor	IDA		Mouse	MGI:MGI:6159308|PMID:29628311

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern