Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LDB1
  • Mouse genes Ldb1
  • Rat genes Ldb1
  • Zfish genes ldb1a,ldb1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ldb1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Ldb1	IDA		Mouse	PMID:19011221
Molecular Function	GO:0003682	chromatin binding	Ldb1	IDA		Mouse	PMID:18550854
Molecular Function	GO:0003677	DNA binding	Ldb1	IDA		Mouse	MGI:MGI:3700453|PMID:9391090
Molecular Function	GO:0140297	DNA-binding transcription factor binding	LDB1	IPI	UniProtKB:O75626	Human	PMID:32417234
Molecular Function	GO:0140297	DNA-binding transcription factor binding	Ldb1	IPI	UniProtKB:P50481	Mouse	MGI:MGI:7339313|PMID:18539116
Molecular Function	GO:0019899	enzyme binding	LDB1	IPI	UniProtKB:Q96EB6	Human	PMID:23382074
Molecular Function	GO:0019899	enzyme binding	Ldb1	IPI	UniProtKB:Q9WTV7	Mouse	MGI:MGI:4456957|PMID:11882901
Molecular Function	GO:0042802	identical protein binding	Ldb1	IPI	PR:P70662	Mouse	PMID:19323994
Molecular Function	GO:0030274	LIM domain binding	LDB1	IPI	UniProtKB:O60663	Human	PMID:12792813
Molecular Function	GO:0030274	LIM domain binding	Ldb1	IDA		Mouse	MGI:MGI:894031|PMID:8876198
Molecular Function	GO:0030274	LIM domain binding	Ldb1	IPI	UniProtKB:P29674|UniProtKB:P63006	Mouse	MGI:MGI:3700452|PMID:9468533
Molecular Function	GO:0030274	LIM domain binding	Ldb1	IDA		Mouse	MGI:MGI:3700454|PMID:9315627
Molecular Function	GO:0030274	LIM domain binding	Ldb1	IPI	PR:P50481	Mouse	PMID:9192866
Molecular Function	GO:0030274	LIM domain binding	Ldb1	IPI	PR:P61372	Mouse	PMID:9192866
Molecular Function	GO:0030274	LIM domain binding	ldb1a	IDA		Zfish	PMID:16815859
Molecular Function	GO:0005515	protein binding	LDB1	IPI	UniProtKB:P61968	Human	PMID:15231748
Molecular Function	GO:0005515	protein binding	LDB1	IPI	UniProtKB:P50458	Human	PMID:20211142
Molecular Function	GO:0005515	protein binding	LDB1	IPI	UniProtKB:P25791	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	LDB1	IPI	UniProtKB:O60663-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LDB1	IPI	UniProtKB:P25791	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LDB1	IPI	UniProtKB:P25800	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LDB1	IPI	UniProtKB:P61968	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LDB1	IPI	UniProtKB:Q68G74	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LDB1	IPI	UniProtKB:Q9BWW4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LDB1	IPI	UniProtKB:Q9UPM6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LDB1	IPI	UniProtKB:Q9BWW4	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	LDB1	IPI	UniProtKB:P50458	Human	PMID:35140242
Molecular Function	GO:0005515	protein binding	LDB1	IPI	UniProtKB:Q68G74	Human	PMID:35140242
Molecular Function	GO:0005515	protein binding	LDB1	IPI	UniProtKB:Q9UPM6	Human	PMID:35140242
Molecular Function	GO:0005515	protein binding	Ldb1	IPI	UniProtKB:P61372	Mouse	MGI:MGI:4455093|PMID:20211142
Molecular Function	GO:0005515	protein binding	Ldb1	IPI	UniProtKB:Q15327	Mouse	MGI:MGI:5294529|PMID:20599664
Molecular Function	GO:0005515	protein binding	Ldb1	IPI	UniProtKB:O54988	Mouse	MGI:MGI:5751678|PMID:19675209
Molecular Function	GO:0005515	protein binding	Ldb1	IPI	UniProtKB:O54972|UniProtKB:P22091|UniProtKB:Q60722	Mouse	MGI:MGI:5508258|PMID:16407974
Molecular Function	GO:0005515	protein binding	Ldb1	IPI	UniProtKB:P25801	Mouse	MGI:MGI:3700453|PMID:9391090
Molecular Function	GO:0005515	protein binding	Ldb1	IPI	UniProtKB:P50481|UniProtKB:P61372	Mouse	MGI:MGI:5508589|PMID:18583962
Molecular Function	GO:0005515	protein binding	Ldb1	IPI	UniProtKB:Q9R1R0	Mouse	MGI:MGI:3851324|PMID:10393337
Molecular Function	GO:0005515	protein binding	Ldb1	IPI	UniProtKB:P22091	Mouse	MGI:MGI:4412329|PMID:19799863
Molecular Function	GO:0005515	protein binding	Ldb1	IPI	UniProtKB:P63006	Mouse	PMID:26494787
Molecular Function	GO:0005515	protein binding	Ldb1	IPI	PR:P61969	Mouse	PMID:19666821
Molecular Function	GO:0005515	protein binding	Ldb1	IPI	PR:P61969	Mouse	PMID:17991461
Molecular Function	GO:0005515	protein binding	Ldb1	IPI	PR:P61372	Mouse	PMID:19666821
Molecular Function	GO:0005515	protein binding	Ldb1	IPI	UniProtKB:P23769	Mouse	PMID:19323994
Molecular Function	GO:0005515	protein binding	Ldb1	IPI	PR:P63006	Mouse	PMID:8918878
Molecular Function	GO:0005515	protein binding	Ldb1	IPI	PR:Q9Z0S2	Mouse	PMID:17991461
Molecular Function	GO:0005515	protein binding	Ldb1	IPI	MGI:MGI:1919725	Mouse	PMID:19323994
Molecular Function	GO:0005515	protein binding	Ldb1	IPI	PR:P61969	Mouse	PMID:9860983
Molecular Function	GO:0005515	protein binding	Ldb1	IPI	RGD:61957	Rat	PMID:9315627|RGD:1581795
Molecular Function	GO:0005515	protein binding	ldb1a	IPI	ZFIN:ZDB-GENE-990415-138	Zfish	PMID:16815859
Molecular Function	GO:0042803	protein homodimerization activity	Ldb1	IDA		Mouse	MGI:MGI:3700452|PMID:9468533
Molecular Function	GO:0042803	protein homodimerization activity	Ldb1	IDA		Mouse	MGI:MGI:3700454|PMID:9315627
Molecular Function	GO:0043621	protein self-association	Ldb1	IPI	PR:P70662	Mouse	PMID:19323994
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	LDB1	IPI	UniProtKB:P25791	Human	PMID:16314316
Molecular Function	GO:0003713	transcription coactivator activity	Ldb1	IMP		Mouse	MGI:MGI:7339313|PMID:18539116
Cellular Component	GO:1990907	beta-catenin-TCF complex	LDB1	IDA		Human	PMID:28296634
Cellular Component	GO:0031252	cell leading edge	Ldb1	IDA		Mouse	MGI:MGI:5751678|PMID:19675209
Cellular Component	GO:0000785	chromatin	LDB1	IDA		Human	PMID:20855495
Cellular Component	GO:0005634	nucleus	Ldb1	IDA		Mouse	MGI:MGI:894031|PMID:8876198
Cellular Component	GO:0005634	nucleus	Ldb1	IDA		Mouse	MGI:MGI:3700453|PMID:9391090
Cellular Component	GO:0005634	nucleus	Ldb1	IDA		Mouse	PMID:19011221
Cellular Component	GO:0005634	nucleus	Ldb1	IDA		Rat	PMID:9315627|RGD:1581795
Cellular Component	GO:0005634	nucleus	ldb1a	IDA		Zfish	PMID:16815859
Cellular Component	GO:0032991	protein-containing complex	Ldb1	IPI	UniProtKB:P25801	Mouse	MGI:MGI:3700453|PMID:9391090
Cellular Component	GO:0032991	protein-containing complex	Ldb1	IPI	UniProtKB:P22091	Mouse	MGI:MGI:3700453|PMID:9391090
Cellular Component	GO:0032991	protein-containing complex	Ldb1	IDA		Mouse	MGI:MGI:3578570|PMID:15857913
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	Ldb1	IDA		Mouse	PMID:9860983
Cellular Component	GO:0005667	transcription regulator complex	LDB1	IDA		Human	PMID:16314316
Cellular Component	GO:0005667	transcription regulator complex	Ldb1	IMP		Mouse	MGI:MGI:7339313|PMID:18539116
Cellular Component	GO:0005667	transcription regulator complex	Ldb1	IDA		Mouse	PMID:26494787
Cellular Component	GO:0005667	transcription regulator complex	Ldb1	IDA		Mouse	PMID:19323994
Biological Process	GO:0009948	anterior/posterior axis specification	Ldb1	IMP	MGI:MGI:2449177	Mouse	PMID:12490556
Biological Process	GO:0007155	cell adhesion	Ldb1	IGI	MGI:MGI:109360	Mouse	PMID:17991461
Biological Process	GO:0022607	cellular component assembly	Ldb1	IGI	MGI:MGI:109360	Mouse	PMID:17991461
Biological Process	GO:0021702	cerebellar Purkinje cell differentiation	Ldb1	IMP	MGI:MGI:3719683	Mouse	PMID:17664423
Biological Process	GO:0021549	cerebellum development	Ldb1	IMP	MGI:MGI:3719683	Mouse	PMID:17664423
Biological Process	GO:0010669	epithelial structure maintenance	Ldb1	IGI	MGI:MGI:894670	Mouse	PMID:17991461
Biological Process	GO:0001702	gastrulation with mouth forming second	Ldb1	IMP	MGI:MGI:2449177	Mouse	PMID:12490556
Biological Process	GO:0001942	hair follicle development	Ldb1	IGI	MGI:MGI:109360	Mouse	PMID:17991461
Biological Process	GO:0060322	head development	Ldb1	IGI	UniProtKB:Q9D032	Mouse	MGI:MGI:3578570|PMID:15857913
Biological Process	GO:0043973	histone H3-K4 acetylation	Ldb1	IMP		Mouse	MGI:MGI:4834059|PMID:20570862
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	LDB1	IDA		Human	PMID:10767331
Biological Process	GO:0045647	negative regulation of erythrocyte differentiation	Ldb1	IMP		Mouse	MGI:MGI:3700453|PMID:9391090
Biological Process	GO:0030182	neuron differentiation	Ldb1	IEP		Mouse	MGI:MGI:894031|PMID:8876198
Biological Process	GO:0045785	positive regulation of cell adhesion	Ldb1	IGI	MGI:MGI:109360	Mouse	PMID:17991461
Biological Process	GO:0046985	positive regulation of hemoglobin biosynthetic process	Ldb1	IMP		Mouse	MGI:MGI:4834059|PMID:20570862
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	LDB1	IMP		Human	PMID:20855495
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ldb1	IMP		Mouse	MGI:MGI:4834059|PMID:20570862
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ldb1	IMP		Mouse	MGI:MGI:7339313|PMID:18539116
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ldb1	IGI	MGI:MGI:98510	Mouse	PMID:18184866
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ldb1	IGI	MGI:MGI:102673	Mouse	PMID:9192866
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ldb1	IGI	MGI:MGI:95662	Mouse	PMID:18184866
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ldb1	IGI	MGI:MGI:98480	Mouse	PMID:18184866
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ldb1	IGI	MGI:MGI:109360	Mouse	PMID:17991461
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ldb1	IGI	MGI:MGI:107374	Mouse	PMID:9192866
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ldb1	IGI	MGI:MGI:1919725	Mouse	PMID:19323994
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ldb1	IMP		Mouse	PMID:9192866
Biological Process	GO:0030334	regulation of cell migration	Ldb1	IDA		Mouse	MGI:MGI:5751678|PMID:19675209
Biological Process	GO:0051893	regulation of focal adhesion assembly	Ldb1	IDA		Mouse	MGI:MGI:5751678|PMID:19675209
Biological Process	GO:0043549	regulation of kinase activity	Ldb1	IDA		Mouse	MGI:MGI:5751678|PMID:19675209
Biological Process	GO:0034243	regulation of transcription elongation by RNA polymerase II	Ldb1	IMP		Mouse	MGI:MGI:4834059|PMID:20570862
Biological Process	GO:0035019	somatic stem cell population maintenance	Ldb1	IGI	MGI:MGI:109360	Mouse	PMID:17991461
Biological Process	GO:0006366	transcription by RNA polymerase II	Ldb1	IDA		Mouse	MGI:MGI:3578570|PMID:15857913
Biological Process	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	Ldb1	IMP		Mouse	MGI:MGI:4834059|PMID:20570862
Biological Process	GO:0016055	Wnt signaling pathway	Ldb1	IMP	MGI:MGI:2449177	Mouse	PMID:12490556

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern