Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LEF1
  • Mouse genes Lef1
  • Rat genes Lef1
  • Zfish genes lef1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lef1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070016	armadillo repeat domain binding	LEF1	IPI	UniProtKB:Q02248	Human	PMID:12408825
Molecular Function	GO:0008013	beta-catenin binding	LEF1	IPI	UniProtKB:P35222	Human	PMID:10825188
Molecular Function	GO:0008013	beta-catenin binding	LEF1	IPI	UniProtKB:Q02248	Human	PMID:12408825
Molecular Function	GO:0008013	beta-catenin binding	LEF1	IPI	UniProtKB:P35222	Human	PMID:18936100
Molecular Function	GO:0008013	beta-catenin binding	LEF1	IPI	UniProtKB:P35222	Human	PMID:20123964
Molecular Function	GO:0008013	beta-catenin binding	LEF1	IPI	UniProtKB:P35222	Human	PMID:20360943
Molecular Function	GO:0008013	beta-catenin binding	LEF1	IDA		Human	PMID:9488439
Molecular Function	GO:0070742	C2H2 zinc finger domain binding	LEF1	IPI	UniProtKB:P23771	Human	PMID:18445004
Molecular Function	GO:0003682	chromatin binding	Lef1	IDA		Mouse	PMID:15024079
Molecular Function	GO:0003682	chromatin binding	Lef1	IDA		Mouse	PMID:16818445
Molecular Function	GO:0003682	chromatin binding	Lef1	IDA		Mouse	PMID:18202148
Molecular Function	GO:0003682	chromatin binding	Lef1	IDA		Mouse	PMID:16678101
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	Lef1	IDA		Mouse	PMID:15545629
Molecular Function	GO:0003677	DNA binding	Lef1	IDA		Mouse	MGI:MGI:3690807|PMID:7774816
Molecular Function	GO:0003677	DNA binding	Lef1	IDA		Mouse	PMID:16936075
Molecular Function	GO:0008301	DNA binding, bending	Lef1	EXP		Mouse	MGI:MGI:7310013|PMID:15236581
Molecular Function	GO:0008301	DNA binding, bending	Lef1	IDA		Mouse	MGI:MGI:3690807|PMID:7774816
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	LEF1	IMP		Human	PMID:23001182
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Lef1	IDA		Mouse	MGI:MGI:5572893|PMID:12244173
Molecular Function	GO:0003700	DNA-binding transcription factor activity	LEF1	IDA		Human	PMID:11751639
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Lef1	IDA		Mouse	PMID:16936075
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Lef1	IDA		Mouse	PMID:15545629
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Lef1	IDA		Mouse	PMID:11696550
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	LEF1	IDA		Human	PMID:18794125
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Lef1	IGI	MGI:MGI:88276	Mouse	PMID:15729346
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Lef1	IGI	MGI:MGI:97487	Mouse	PMID:15729346
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Lef1	IGI	MGI:MGI:104633	Mouse	PMID:15729346
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Lef1	IMP		Mouse	PMID:30659184
Molecular Function	GO:0045295	gamma-catenin binding	LEF1	IPI	UniProtKB:P14923	Human	PMID:14661054
Molecular Function	GO:0042393	histone binding	LEF1	IPI	UniProtKB:Q13547	Human	PMID:20363964
Molecular Function	GO:0042826	histone deacetylase binding	LEF1	IPI	UniProtKB:Q13547	Human	PMID:18936100
Molecular Function	GO:0030331	nuclear estrogen receptor binding	LEF1	IDA		Human	PMID:18794125
Molecular Function	GO:0003676	nucleic acid binding	Lef1	EXP		Mouse	MGI:MGI:7310013|PMID:15236581
Molecular Function	GO:0005515	protein binding	LEF1	IPI	UniProtKB:P70331	Human	PMID:12192039
Molecular Function	GO:0005515	protein binding	LEF1	IPI	UniProtKB:P70331-2	Human	PMID:12192039
Molecular Function	GO:0005515	protein binding	LEF1	IPI	UniProtKB:Q9P1T7	Human	PMID:12192039
Molecular Function	GO:0005515	protein binding	LEF1	IPI	UniProtKB:P35222	Human	PMID:17510365
Molecular Function	GO:0005515	protein binding	LEF1	IPI	UniProtKB:P35222	Human	PMID:17517646
Molecular Function	GO:0005515	protein binding	LEF1	IPI	UniProtKB:P35222	Human	PMID:18077326
Molecular Function	GO:0005515	protein binding	LEF1	IPI	UniProtKB:P49789	Human	PMID:18077326
Molecular Function	GO:0005515	protein binding	LEF1	IPI	UniProtKB:Q9NYF0	Human	PMID:18936100
Molecular Function	GO:0005515	protein binding	LEF1	IPI	UniProtKB:P16371	Human	PMID:19460168
Molecular Function	GO:0005515	protein binding	LEF1	IPI	UniProtKB:P35222	Human	PMID:20123964
Molecular Function	GO:0005515	protein binding	LEF1	IPI	UniProtKB:P35222	Human	PMID:21743491
Molecular Function	GO:0005515	protein binding	LEF1	IPI	UniProtKB:P08069	Human	PMID:22261717
Molecular Function	GO:0005515	protein binding	LEF1	IPI	UniProtKB:P14317	Human	PMID:23001182
Molecular Function	GO:0005515	protein binding	LEF1	IPI	UniProtKB:Q16236	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	Lef1	IPI	UniProtKB:Q61473	Mouse	MGI:MGI:4887291|PMID:20802155
Molecular Function	GO:0005515	protein binding	Lef1	IPI	UniProtKB:O75564	Mouse	MGI:MGI:5508728|PMID:21399610
Molecular Function	GO:0005515	protein binding	Lef1	IPI	UniProtKB:Q15038	Mouse	MGI:MGI:5009493|PMID:19304756
Molecular Function	GO:0005515	protein binding	Lef1	IPI	UniProtKB:Q02248	Mouse	MGI:MGI:3694173|PMID:16293619
Molecular Function	GO:0005515	protein binding	Lef1	IPI	UniProtKB:P30681|UniProtKB:P35222	Mouse	MGI:MGI:4361752|PMID:19805379
Molecular Function	GO:0005515	protein binding	Lef1	IPI	PR:Q62441	Mouse	PMID:15729346
Molecular Function	GO:0005515	protein binding	Lef1	IPI	PR:P19785	Mouse	PMID:18202148
Molecular Function	GO:0005515	protein binding	Lef1	IPI	PR:Q9Z1J1	Mouse	PMID:18202148
Molecular Function	GO:0005515	protein binding	Lef1	IPI	PR:Q9JM05	Mouse	PMID:11731474
Molecular Function	GO:0005515	protein binding	Lef1	IPI	PR:Q3TVI8	Mouse	PMID:30659184
Molecular Function	GO:0005515	protein binding	Lef1	IPI	PR:O35137	Mouse	PMID:11696550
Molecular Function	GO:0005515	protein binding	Lef1	IPI	RGD:70487	Rat	PMID:17170212|RGD:1599635
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	LEF1	IDA		Human	PMID:16344550
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	LEF1	IDA		Human	PMID:17063141
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	LEF1	IDA		Human	PMID:18579517
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	LEF1	IDA		Human	PMID:19351848
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	LEF1	IDA		Human	PMID:20128911
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	LEF1	IDA		Human	PMID:20363964
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	LEF1	IDA		Human	PMID:7657162
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	LEF1	IDA		Human	PMID:9308964
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Lef1	IDA		Mouse	MGI:MGI:4836133|PMID:20371816
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Lef1	IDA		Mouse	MGI:MGI:5572893|PMID:12244173
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Lef1	IDA		Mouse	PMID:18684741
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Lef1	IDA		Mouse	PMID:15545629
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	LEF1	IDA		Human	PMID:23001182
Molecular Function	GO:0043565	sequence-specific DNA binding	LEF1	IDA		Human	PMID:10825188
Molecular Function	GO:0043565	sequence-specific DNA binding	Lef1	IDA		Mouse	PMID:21750544
Molecular Function	GO:0043565	sequence-specific DNA binding	Lef1	IDA		Mouse	PMID:22235033
Molecular Function	GO:0043565	sequence-specific DNA binding	lef1	IPI	ZFIN:ZDB-GENE-041203-2	Zfish	PMID:18950487
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	LEF1	IDA		Human	PMID:28473536
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Lef1	IDA		Mouse	PMID:7537238
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Lef1	IDA		Mouse	PMID:12551949
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Lef1	IDA		Mouse	PMID:19056892
Molecular Function	GO:0001222	transcription corepressor binding	LEF1	IPI	UniProtKB:Q04724	Human	PMID:9751710
Molecular Function	GO:0008134	transcription factor binding	Lef1	IPI	PR:Q08775	Mouse	PMID:12551949
Molecular Function	GO:0008134	transcription factor binding	Lef1	IPI	PR:Q03347	Mouse	PMID:12551949
Molecular Function	GO:0140416	transcription regulator inhibitor activity	LEF1	IDA		Human	PMID:18794125
Cellular Component	GO:1990907	beta-catenin-TCF complex	LEF1	IPI		Human	PMID:20123964
Cellular Component	GO:1990907	beta-catenin-TCF complex	LEF1	IPI	UniProtKB:P35222	Human	PMID:18936100
Cellular Component	GO:1990907	beta-catenin-TCF complex	Lef1	IDA		Mouse	MGI:MGI:4836133|PMID:20371816
Cellular Component	GO:0005737	cytoplasm	LEF1	IDA		Human	PMID:19402906
Cellular Component	GO:0005737	cytoplasm	LEF1	IDA		Human	PMID:23001182
Cellular Component	GO:0005737	cytoplasm	Lef1	IDA		Mouse	MGI:MGI:5571208|PMID:24681597
Cellular Component	GO:0005737	cytoplasm	Lef1	IDA		Mouse	PMID:14623238
Cellular Component	GO:0005634	nucleus	LEF1	IDA		Human	PMID:17063141
Cellular Component	GO:0005634	nucleus	LEF1	IDA		Human	PMID:18579517
Cellular Component	GO:0005634	nucleus	LEF1	IDA		Human	PMID:18936100
Cellular Component	GO:0005634	nucleus	LEF1	IDA		Human	PMID:20123964
Cellular Component	GO:0005634	nucleus	LEF1	IDA		Human	PMID:23001182
Cellular Component	GO:0005634	nucleus	Lef1	IDA		Mouse	MGI:MGI:4836133|PMID:20371816
Cellular Component	GO:0005634	nucleus	Lef1	IDA		Mouse	MGI:MGI:4834989|PMID:18579517
Cellular Component	GO:0005634	nucleus	Lef1	IDA		Mouse	MGI:MGI:5571208|PMID:24681597
Cellular Component	GO:0005634	nucleus	Lef1	IDA		Mouse	MGI:MGI:3656361|PMID:16936075
Cellular Component	GO:0005634	nucleus	Lef1	IPI	PR:Q3TVI8	Mouse	PMID:30659184
Cellular Component	GO:0005634	nucleus	Lef1	IDA		Mouse	PMID:30659184
Cellular Component	GO:0005634	nucleus	Lef1	IDA		Mouse	PMID:14623238
Cellular Component	GO:0005634	nucleus	Lef1	IDA		Mouse	PMID:22935613
Cellular Component	GO:0005634	nucleus	Lef1	IDA		Mouse	PMID:21464233
Cellular Component	GO:0005634	nucleus	Lef1	IDA		Mouse	PMID:12551949
Cellular Component	GO:0005634	nucleus	Lef1	IDA		Mouse	PMID:18202148
Cellular Component	GO:0005634	nucleus	Lef1	IDA		Mouse	PMID:7537238
Cellular Component	GO:0005634	nucleus	Lef1	IDA		Mouse	PMID:10498690
Cellular Component	GO:0005634	nucleus	Lef1	IDA		Rat	PMID:9539744|RGD:2298721
Cellular Component	GO:0032993	protein-DNA complex	LEF1	IDA		Human	PMID:10825188
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	Lef1	IPI		Mouse	MGI:MGI:6827205|PMID:21075118
Cellular Component	GO:0005667	transcription regulator complex	LEF1	IDA		Human	PMID:11751639
Cellular Component	GO:0005667	transcription regulator complex	LEF1	IDA		Human	PMID:23001182
Cellular Component	GO:0005667	transcription regulator complex	Lef1	IDA		Mouse	PMID:30659184
Cellular Component	GO:0005667	transcription regulator complex	Lef1	IPI	PR:O35137	Mouse	PMID:11696550
Biological Process	GO:0046632	alpha-beta T cell differentiation	Lef1	IGI	MGI:MGI:98507	Mouse	PMID:9462507
Biological Process	GO:0060033	anatomical structure regression	Lef1	IMP	MGI:MGI:1926601	Mouse	PMID:16163358
Biological Process	GO:0031100	animal organ regeneration	Lef1	IEP		Rat	PMID:18990226|RGD:4110831
Biological Process	GO:1902262	apoptotic process involved in blood vessel morphogenesis	Lef1	IMP	MGI:MGI:1926601	Mouse	PMID:16163358
Biological Process	GO:0060561	apoptotic process involved in morphogenesis	Lef1	IMP	MGI:MGI:1926601	Mouse	PMID:15649466
Biological Process	GO:0042100	B cell proliferation	Lef1	IMP	MGI:MGI:1926601	Mouse	PMID:10933391
Biological Process	GO:0030509	BMP signaling pathway	Lef1	IDA		Mouse	PMID:9769173
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	Lef1	IMP	MGI:MGI:1926601	Mouse	PMID:19154719
Biological Process	GO:0060070	canonical Wnt signaling pathway	LEF1	IDA		Human	PMID:10644691
Biological Process	GO:0060070	canonical Wnt signaling pathway	LEF1	IDA		Human	PMID:11751639
Biological Process	GO:0060070	canonical Wnt signaling pathway	LEF1	IDA		Human	PMID:20123964
Biological Process	GO:0060070	canonical Wnt signaling pathway	Lef1	IDA		Mouse	MGI:MGI:3656361|PMID:16936075
Biological Process	GO:0060070	canonical Wnt signaling pathway	Lef1	IGI	MGI:MGI:98956	Mouse	PMID:10933391
Biological Process	GO:0060070	canonical Wnt signaling pathway	Lef1	IMP	MGI:MGI:1926601	Mouse	PMID:16678815
Biological Process	GO:0060070	canonical Wnt signaling pathway	Lef1	IDA		Mouse	PMID:9769173
Biological Process	GO:0060070	canonical Wnt signaling pathway	Lef1	IGI	MGI:MGI:1202879	Mouse	PMID:17699607
Biological Process	GO:0060070	canonical Wnt signaling pathway	lef1	IMP	ZFIN:ZDB-MRPHLNO-100125-1	Zfish	PMID:21862557
Biological Process	GO:0060070	canonical Wnt signaling pathway	lef1	IGI	ZFIN:ZDB-GENE-990714-26,ZFIN:ZDB-MRPHLNO-071205-3	Zfish	PMID:16890162
Biological Process	GO:0060070	canonical Wnt signaling pathway	lef1	IMP		Zfish	PMID:11784107
Biological Process	GO:0060070	canonical Wnt signaling pathway	lef1	IMP	ZFIN:ZDB-MRPHLNO-060214-5	Zfish	PMID:22373574
Biological Process	GO:0033336	caudal fin development	lef1	IMP	ZFIN:ZDB-GENO-110922-2	Zfish	PMID:21862556
Biological Process	GO:0007155	cell adhesion	Lef1	IEP		Rat	PMID:9539744|RGD:2298721
Biological Process	GO:0060326	cell chemotaxis	LEF1	IDA		Human	PMID:19576624
Biological Process	GO:0048468	cell development	Lef1	IGI	MGI:MGI:104554	Mouse	PMID:15729346
Biological Process	GO:0071345	cellular response to cytokine stimulus	LEF1	IMP		Human	PMID:23001182
Biological Process	GO:0071353	cellular response to interleukin-4	LEF1	IDA		Human	PMID:18579517
Biological Process	GO:0060710	chorio-allantoic fusion	Lef1	IGI	MGI:MGI:98504	Mouse	PMID:10090727
Biological Process	GO:0021542	dentate gyrus development	Lef1	IMP	MGI:MGI:1933764	Mouse	PMID:10631168
Biological Process	GO:0030326	embryonic limb morphogenesis	Lef1	IGI	MGI:MGI:98504	Mouse	PMID:10090727
Biological Process	GO:1904019	epithelial cell apoptotic process	Lef1	IMP	MGI:MGI:1926601	Mouse	PMID:15649466
Biological Process	GO:0001837	epithelial to mesenchymal transition	Lef1	IMP		Mouse	MGI:MGI:2683382|PMID:14691138
Biological Process	GO:0060325	face morphogenesis	Lef1	IGI	MGI:MGI:1202879	Mouse	PMID:17699607
Biological Process	GO:0033333	fin development	lef1	IMP	ZFIN:ZDB-GENO-111013-9	Zfish	PMID:21862557
Biological Process	GO:0033334	fin morphogenesis	lef1	IMP	ZFIN:ZDB-GENO-121211-4	Zfish	PMID:22975330
Biological Process	GO:0031101	fin regeneration	lef1	IMP	ZFIN:ZDB-MRPHLNO-060214-5	Zfish	PMID:19015519
Biological Process	GO:0021873	forebrain neuroblast division	Lef1	IGI	MGI:MGI:1298218	Mouse	PMID:14715945
Biological Process	GO:0021879	forebrain neuron differentiation	lef1	IMP	ZFIN:ZDB-MRPHLNO-060214-6	Zfish	PMID:18799544
Biological Process	GO:0021861	forebrain radial glial cell differentiation	Lef1	IGI	MGI:MGI:1298218	Mouse	PMID:14715945
Biological Process	GO:0021943	formation of radial glial scaffolds	Lef1	IGI	MGI:MGI:1298218	Mouse	PMID:14715945
Biological Process	GO:0021766	hippocampus development	Lef1	IMP	MGI:MGI:1933764	Mouse	PMID:10631168
Biological Process	GO:0021979	hypothalamus cell differentiation	lef1	IMP	ZFIN:ZDB-GENO-121211-4	Zfish	PMID:22975330
Biological Process	GO:0021854	hypothalamus development	lef1	IMP	ZFIN:ZDB-MRPHLNO-060214-6	Zfish	PMID:17050627
Biological Process	GO:0001822	kidney development	Lef1	IEP		Rat	PMID:17329570|RGD:2298718
Biological Process	GO:0030879	mammary gland development	Lef1	IMP	MGI:MGI:1926601	Mouse	PMID:16678815
Biological Process	GO:0055001	muscle cell development	lef1	IMP		Zfish	PMID:19517013
Biological Process	GO:0043066	negative regulation of apoptotic process	LEF1	IMP		Human	PMID:20360943
Biological Process	GO:0071866	negative regulation of apoptotic process in bone marrow cell	LEF1	IMP		Human	PMID:17063141
Biological Process	GO:0043392	negative regulation of DNA binding	LEF1	IDA		Human	PMID:18445004
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	LEF1	IMP		Human	PMID:18579517
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	LEF1	IDA		Human	PMID:18794125
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Lef1	IDA		Mouse	PMID:12551949
Biological Process	GO:0032696	negative regulation of interleukin-13 production	LEF1	IDA		Human	PMID:18445004
Biological Process	GO:0032713	negative regulation of interleukin-4 production	LEF1	IDA		Human	PMID:18445004
Biological Process	GO:0032714	negative regulation of interleukin-5 production	LEF1	IDA		Human	PMID:18445004
Biological Process	GO:0045843	negative regulation of striated muscle tissue development	Lef1	IDA		Mouse	PMID:16936075
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	LEF1	IMP		Human	PMID:20363964
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Lef1	IDA		Mouse	PMID:16678101
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Lef1	IDA		Mouse	PMID:19056892
Biological Process	GO:0001755	neural crest cell migration	lef1	IMP	ZFIN:ZDB-MRPHLNO-060214-5	Zfish	PMID:16228014
Biological Process	GO:0022008	neurogenesis	lef1	IGI	ZFIN:ZDB-MRPHLNO-050809-5,ZFIN:ZDB-MRPHLNO-060214-6	Zfish	PMID:19946145
Biological Process	GO:0022008	neurogenesis	lef1	IGI	ZFIN:ZDB-MRPHLNO-100524-11,ZFIN:ZDB-MRPHLNO-100524-9	Zfish	PMID:19946145
Biological Process	GO:0022008	neurogenesis	lef1	IGI	ZFIN:ZDB-MRPHLNO-050809-5,ZFIN:ZDB-MRPHLNO-100524-11	Zfish	PMID:19946145
Biological Process	GO:0022008	neurogenesis	lef1	IGI	ZFIN:ZDB-MRPHLNO-060214-6,ZFIN:ZDB-MRPHLNO-100524-9	Zfish	PMID:19946145
Biological Process	GO:0030223	neutrophil differentiation	LEF1	IMP		Human	PMID:17063141
Biological Process	GO:0071895	odontoblast differentiation	Lef1	IMP		Rat	PMID:20425127|RGD:4110819
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	Lef1	IMP	MGI:MGI:1926601	Mouse	PMID:15649466
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	Lef1	IMP	MGI:MGI:1926601	Mouse	PMID:12502739
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	Lef1	IGI	MGI:MGI:1202879	Mouse	PMID:17699607
Biological Process	GO:0001649	osteoblast differentiation	LEF1	IEP		Human	PMID:20128911
Biological Process	GO:0048341	paraxial mesoderm formation	Lef1	IGI	MGI:MGI:98504	Mouse	PMID:10090727
Biological Process	GO:0033339	pectoral fin development	lef1	IMP	ZFIN:ZDB-GENO-110922-2	Zfish	PMID:21862556
Biological Process	GO:0043923	positive regulation by host of viral transcription	LEF1	IDA		Human	PMID:7657162
Biological Process	GO:0030335	positive regulation of cell migration	LEF1	IMP		Human	PMID:20018240
Biological Process	GO:0071864	positive regulation of cell proliferation in bone marrow	LEF1	IMP		Human	PMID:17063141
Biological Process	GO:1902732	positive regulation of chondrocyte proliferation	Lef1	IMP		Mouse	PMID:30659184
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	LEF1	IDA		Human	PMID:10644691
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	LEF1	IDA		Human	PMID:17063141
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	LEF1	IMP		Human	PMID:19351848
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	LEF1	IDA		Human	PMID:19620402
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	LEF1	IDA		Human	PMID:20128911
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	LEF1	IDA		Human	PMID:7657162
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Lef1	IDA		Mouse	PMID:10631168
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Lef1	IMP		Mouse	PMID:30659184
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Lef1	IMP	MGI:MGI:1926601	Mouse	PMID:10933391
Biological Process	GO:0010718	positive regulation of epithelial to mesenchymal transition	LEF1	IMP		Human	PMID:20018240
Biological Process	GO:0045588	positive regulation of gamma-delta T cell differentiation	Lef1	IMP		Mouse	MGI:MGI:5486619|PMID:23562159
Biological Process	GO:0010628	positive regulation of gene expression	LEF1	IDA		Human	PMID:16344550
Biological Process	GO:0010628	positive regulation of gene expression	lef1	IMP	ZFIN:ZDB-MRPHLNO-060214-6	Zfish	PMID:18950487
Biological Process	GO:0030854	positive regulation of granulocyte differentiation	LEF1	IDA		Human	PMID:19620402
Biological Process	GO:0030854	positive regulation of granulocyte differentiation	LEF1	IMP		Human	PMID:23001182
Biological Process	GO:0050769	positive regulation of neurogenesis	lef1	IMP	ZFIN:ZDB-GENO-121211-4	Zfish	PMID:22975330
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	LEF1	IDA		Human	PMID:11751639
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	LEF1	IDA		Human	PMID:23001182
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	LEF1	IMP		Human	PMID:23001182
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Lef1	IGI	UniProtKB:Q02248	Mouse	MGI:MGI:4836133|PMID:20371816
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Lef1	IDA		Mouse	MGI:MGI:5572893|PMID:12244173
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Lef1	IDA		Mouse	MGI:MGI:3656361|PMID:16936075
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Lef1	IGI	MGI:MGI:1338823	Mouse	PMID:15094381
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Lef1	IGI	MGI:MGI:97489	Mouse	PMID:15094381
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Lef1	IDA		Mouse	PMID:15545629
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Lef1	IGI	MGI:MGI:97249	Mouse	PMID:15094381
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Lef1	IMP	MGI:MGI:1926601	Mouse	PMID:17284610
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Lef1	IDA		Mouse	PMID:12475749
Biological Process	GO:0030177	positive regulation of Wnt signaling pathway	Lef1	IMP		Mouse	PMID:30659184
Biological Process	GO:0048916	posterior lateral line development	lef1	IMP	ZFIN:ZDB-GENO-111013-9	Zfish	PMID:21862557
Biological Process	GO:0048916	posterior lateral line development	lef1	IMP	ZFIN:ZDB-GENO-110922-2	Zfish	PMID:21862556
Biological Process	GO:0048922	posterior lateral line neuromast deposition	lef1	IMP	ZFIN:ZDB-GENO-110922-2	Zfish	PMID:21862556
Biological Process	GO:0048919	posterior lateral line neuromast development	lef1	IMP	ZFIN:ZDB-MRPHLNO-100125-1	Zfish	PMID:23637337
Biological Process	GO:0071168	protein localization to chromatin	LEF1	IMP		Human	PMID:20363964
Biological Process	GO:0060784	regulation of cell proliferation involved in tissue homeostasis	lef1	IMP	ZFIN:ZDB-GENO-111013-9	Zfish	PMID:21862557
Biological Process	GO:0022407	regulation of cell-cell adhesion	Lef1	IMP	MGI:MGI:1926601	Mouse	PMID:19154719
Biological Process	GO:0006355	regulation of DNA-templated transcription	Lef1	IMP		Mouse	MGI:MGI:5486619|PMID:23562159
Biological Process	GO:1900052	regulation of retinoic acid biosynthetic process	lef1	IGI	ZFIN:ZDB-GENO-090916-1,ZFIN:ZDB-MRPHLNO-060214-6	Zfish	PMID:20850014
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Lef1	IDA		Mouse	PMID:11696550
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	lef1	IGI	ZFIN:ZDB-GENE-050222-4	Zfish	PMID:17215296
Biological Process	GO:0030111	regulation of Wnt signaling pathway	Lef1	IGI	MGI:MGI:98504	Mouse	PMID:10090727
Biological Process	GO:0010226	response to lithium ion	Lef1	IEP		Rat	PMID:17329570|RGD:2298718
Biological Process	GO:0014070	response to organic cyclic compound	Lef1	IEP		Rat	PMID:17329570|RGD:2298718
Biological Process	GO:0062009	secondary palate development	Lef1	IMP		Mouse	MGI:MGI:2683382|PMID:14691138
Biological Process	GO:0050909	sensory perception of taste	Lef1	IMP	MGI:MGI:1926601	Mouse	PMID:17284610
Biological Process	GO:0043588	skin development	Lef1	IEP		Rat	PMID:17244330|RGD:2298719
Biological Process	GO:0001756	somitogenesis	Lef1	IGI	MGI:MGI:98504	Mouse	PMID:10090727
Biological Process	GO:0001756	somitogenesis	Lef1	IMP	MGI:MGI:1933764	Mouse	PMID:15545629
Biological Process	GO:0001756	somitogenesis	lef1	IMP		Zfish	PMID:19517013
Biological Process	GO:0002040	sprouting angiogenesis	Lef1	IMP	MGI:MGI:1926601	Mouse	PMID:19154719
Biological Process	GO:0033153	T cell receptor V(D)J recombination	Lef1	IGI	MGI:MGI:98507	Mouse	PMID:9462507
Biological Process	GO:0045063	T-helper 1 cell differentiation	Lef1	IDA		Mouse	MGI:MGI:4834989|PMID:18579517
Biological Process	GO:0043586	tongue development	Lef1	IMP	MGI:MGI:1926601	Mouse	PMID:17284610
Biological Process	GO:0061153	trachea gland development	Lef1	IMP	MGI:MGI:1926601	Mouse	PMID:10498680
Biological Process	GO:0006366	transcription by RNA polymerase II	Lef1	IMP	MGI:MGI:1926601	Mouse	PMID:17284610
Biological Process	GO:0001944	vasculature development	Lef1	IMP	MGI:MGI:1926601	Mouse	PMID:16163358

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern