Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LEMD2
  • Mouse genes Lemd2
  • Rat genes Lemd2
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lemd2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	LEMD2	IPI	UniProtKB:Q8WUX9	Human	PMID:28242692
Cellular Component	GO:0000785	chromatin	LEMD2	IDA		Human	PMID:28242692
Cellular Component	GO:0005783	endoplasmic reticulum	LEMD2	IDA		Human	PMID:28242692
Cellular Component	GO:0016020	membrane	LEMD2	HDA		Human	PMID:19946888
Cellular Component	GO:0005635	nuclear envelope	LEMD2	IDA		Human	PMID:28242692
Cellular Component	GO:0005637	nuclear inner membrane	LEMD2	IDA		Human	PMID:16339967
Cellular Component	GO:0031965	nuclear membrane	LEMD2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0031965	nuclear membrane	Lemd2	IDA		Mouse	PMID:16339967
Biological Process	GO:0060914	heart formation	Lemd2	IMP		Mouse	MGI:MGI:5640886|PMID:25790465
Biological Process	GO:0043409	negative regulation of MAPK cascade	Lemd2	IMP		Mouse	PMID:19720741
Biological Process	GO:0051898	negative regulation of protein kinase B signaling	Lemd2	IMP		Mouse	MGI:MGI:5640886|PMID:25790465
Biological Process	GO:0022008	neurogenesis	Lemd2	IMP		Mouse	MGI:MGI:5640886|PMID:25790465
Biological Process	GO:0006998	nuclear envelope organization	LEMD2	IMP		Human	PMID:17097643
Biological Process	GO:0071168	protein localization to chromatin	LEMD2	IMP		Human	PMID:28242692
Biological Process	GO:0035914	skeletal muscle cell differentiation	LEMD2	IGI	UniProtKB:O08579	Human	PMID:19720741
Biological Process	GO:0035914	skeletal muscle cell differentiation	Lemd2	IMP		Mouse	PMID:19720741

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern