Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LGALS2
  • Mouse genes Lgals2
  • Rat genes Lgals2
  • Zfish genes lgals2a,lgals2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lgals2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016936	galactoside binding	Lgals2	IDA		Rat	PMID:9882446|RGD:633279
Molecular Function	GO:0016936	galactoside binding	lgals2a	IDA		Zfish	PMID:14693912
Molecular Function	GO:0043236	laminin binding	lgals2a	IDA		Zfish	PMID:14693912
Molecular Function	GO:0005515	protein binding	LGALS2	IPI	UniProtKB:O00560	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LGALS2	IPI	UniProtKB:Q9H190	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LGALS2	IPI	UniProtKB:Q9H190	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	LGALS2	IPI	UniProtKB:O00560	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LGALS2	IPI	UniProtKB:Q96HA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LGALS2	IPI	UniProtKB:Q9H190	Human	PMID:32296183
Cellular Component	GO:1990724	galectin complex	LGALS2	IPI		Human	PMID:8262940
Biological Process	GO:0098609	cell-cell adhesion	LGALS2	IDA		Human	PMID:15356130
Biological Process	GO:0043065	positive regulation of apoptotic process	LGALS2	IDA		Human	PMID:15356130
Biological Process	GO:0050729	positive regulation of inflammatory response	Lgals2	IDA		Mouse	MGI:MGI:6814706|PMID:18064431
Biological Process	GO:0050769	positive regulation of neurogenesis	lgals2a	IMP	ZFIN:ZDB-MRPHLNO-101117-6	Zfish	PMID:20071673
Biological Process	GO:0090303	positive regulation of wound healing	lgals2a	IMP	ZFIN:ZDB-MRPHLNO-101117-6	Zfish	PMID:20071673
Biological Process	GO:0048741	skeletal muscle fiber development	lgals2a	IMP	ZFIN:ZDB-MRPHLNO-090717-1	Zfish	PMID:18763034
Biological Process	GO:0002040	sprouting angiogenesis	lgals2b	IGI	ZFIN:ZDB-MRPHLNO-061122-2,ZFIN:ZDB-MRPHLNO-061122-5	Zfish	PMID:17043243
Biological Process	GO:0002040	sprouting angiogenesis	lgals2b	IGI	ZFIN:ZDB-MRPHLNO-061122-3,ZFIN:ZDB-MRPHLNO-061122-4	Zfish	PMID:17043243
Biological Process	GO:0002040	sprouting angiogenesis	lgals2a	IGI	ZFIN:ZDB-MRPHLNO-061122-2,ZFIN:ZDB-MRPHLNO-061122-5	Zfish	PMID:17043243
Biological Process	GO:0002040	sprouting angiogenesis	lgals2a	IGI	ZFIN:ZDB-MRPHLNO-061122-3,ZFIN:ZDB-MRPHLNO-061122-4	Zfish	PMID:17043243
Biological Process	GO:0043029	T cell homeostasis	LGALS2	IDA		Human	PMID:15356130
Biological Process	GO:0001944	vasculature development	lgals2b	IMP	ZFIN:ZDB-MRPHLNO-061122-5	Zfish	PMID:17043243
Biological Process	GO:0001944	vasculature development	lgals2b	IMP	ZFIN:ZDB-MRPHLNO-061122-4	Zfish	PMID:17043243
Biological Process	GO:0001944	vasculature development	lgals2a	IMP	ZFIN:ZDB-MRPHLNO-061122-2	Zfish	PMID:17043243
Biological Process	GO:0001944	vasculature development	lgals2a	IMP	ZFIN:ZDB-MRPHLNO-061122-3	Zfish	PMID:17043243

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern