Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LGR6
  • Mouse genes Lgr6
  • Rat genes Lgr6
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lgr6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	LGR6	IPI	UniProtKB:Q2MKA7	Human	PMID:21727895
Molecular Function	GO:0005515	protein binding	LGR6	IPI	UniProtKB:Q2MKA7	Human	PMID:22615920
Molecular Function	GO:0005515	protein binding	LGR6	IPI	UniProtKB:Q6UXX9	Human	PMID:22615920
Molecular Function	GO:0005515	protein binding	LGR6	IPI	UniProtKB:Q9BXY4	Human	PMID:22615920
Cellular Component	GO:0031982	vesicle	LGR6	IDA		Human	PMID:22615920
Biological Process	GO:1990523	bone regeneration	Lgr6	IMP	MGI:MGI:4438349	Mouse	PMID:26460010
Biological Process	GO:0008283	cell population proliferation	Lgr6	IMP	MGI:MGI:4438349	Mouse	PMID:30936556
Biological Process	GO:0030335	positive regulation of cell migration	LGR6	IDA		Human	PMID:22615920
Biological Process	GO:0030177	positive regulation of Wnt signaling pathway	LGR6	IDA		Human	PMID:22615920
Biological Process	GO:0042246	tissue regeneration	Lgr6	IMP	MGI:MGI:4438349	Mouse	PMID:26460010

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern