Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LHCGR
  • Mouse genes Lhcgr
  • Rat genes Lhcgr
  • Zfish genes lhcgr
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lhcgr

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051117	ATPase binding	Lhcgr	IPI	RGD:2174	Rat	PMID:17588601|RGD:2292598
Molecular Function	GO:0038106	choriogonadotropin hormone binding	Lhcgr	IDA		Mouse	MGI:MGI:5318037|PMID:10493819
Molecular Function	GO:0035472	choriogonadotropin hormone receptor activity	Lhcgr	IDA		Mouse	MGI:MGI:5318037|PMID:10493819
Molecular Function	GO:0035472	choriogonadotropin hormone receptor activity	Lhcgr	IMP	MGI:MGI:2181999	Mouse	PMID:11145748
Molecular Function	GO:0008528	G protein-coupled peptide receptor activity	Lhcgr	IDA		Rat	PMID:2502842|RGD:1566529
Molecular Function	GO:0042802	identical protein binding	Lhcgr	IDA		Rat	PMID:11266505|RGD:1600296
Molecular Function	GO:0042802	identical protein binding	Lhcgr	IPI	RGD:3007	Rat	PMID:2601325|RGD:2292582
Molecular Function	GO:0004964	luteinizing hormone receptor activity	LHCGR	IMP		Human	PMID:11847099
Molecular Function	GO:0004964	luteinizing hormone receptor activity	lhcgr	IDA		Zfish	PMID:15728794
Molecular Function	GO:0017046	peptide hormone binding	Lhcgr	IDA		Rat	PMID:15901736|RGD:2292553
Molecular Function	GO:0017046	peptide hormone binding	Lhcgr	IMP		Rat	PMID:1714448|RGD:2292578
Molecular Function	GO:0017046	peptide hormone binding	Lhcgr	IPI	RGD:1348590	Rat	PMID:2601325|RGD:2292582
Molecular Function	GO:0017046	peptide hormone binding	Lhcgr	IPI	RGD:1348590|RGD:1351942	Rat	PMID:2925659|RGD:2292580
Molecular Function	GO:0017046	peptide hormone binding	Lhcgr	IPI	RGD:1348590	Rat	PMID:3782111|RGD:2292594
Cellular Component	GO:0034451	centriolar satellite	LHCGR	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005737	cytoplasm	Lhcgr	IDA		Rat	PMID:12816543|RGD:2292599
Cellular Component	GO:0005783	endoplasmic reticulum	Lhcgr	IDA		Rat	PMID:16495341|RGD:1600293
Cellular Component	GO:0005768	endosome	Lhcgr	IDA		Rat	PMID:10847593|RGD:2292601
Cellular Component	GO:0005615	extracellular space	Lhcgr	IDA		Rat	PMID:2174034|RGD:2292585
Cellular Component	GO:0005764	lysosome	Lhcgr	IDA		Rat	PMID:10847593|RGD:2292601
Cellular Component	GO:0016020	membrane	Lhcgr	IDA		Rat	PMID:15901736|RGD:2292553
Cellular Component	GO:0005634	nucleus	Lhcgr	IDA		Rat	PMID:12816543|RGD:2292599
Cellular Component	GO:0005886	plasma membrane	LHCGR	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	LHCGR	IDA		Human	PMID:11847099
Cellular Component	GO:0005886	plasma membrane	Lhcgr	IDA		Mouse	MGI:MGI:5318037|PMID:10493819
Cellular Component	GO:0005886	plasma membrane	Lhcgr	IDA		Rat	PMID:16495341|RGD:1600293
Cellular Component	GO:0005886	plasma membrane	Lhcgr	IDA		Rat	PMID:1695568|RGD:2292610
Cellular Component	GO:0043235	receptor complex	Lhcgr	IDA		Rat	PMID:11266505|RGD:1600296
Biological Process	GO:0007190	activation of adenylate cyclase activity	Lhcgr	IDA		Mouse	MGI:MGI:5318037|PMID:10493819
Biological Process	GO:0007190	activation of adenylate cyclase activity	Lhcgr	IDA		Rat	PMID:8440169|RGD:2292602
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	Lhcgr	IDA		Mouse	MGI:MGI:5318037|PMID:10493819
Biological Process	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	Lhcgr	IMP		Rat	PMID:1714448|RGD:2292578
Biological Process	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	Lhcgr	IDA		Rat	PMID:2502842|RGD:1566529
Biological Process	GO:0050482	arachidonic acid secretion	Lhcgr	IDA		Rat	PMID:9291830|RGD:1600299
Biological Process	GO:0071371	cellular response to gonadotropin stimulus	Lhcgr	IDA		Mouse	MGI:MGI:5318037|PMID:10493819
Biological Process	GO:0071373	cellular response to luteinizing hormone stimulus	LHCGR	IMP		Human	PMID:11847099
Biological Process	GO:0007417	central nervous system development	Lhcgr	IEP		Rat	PMID:14581462|RGD:1600294
Biological Process	GO:0050890	cognition	LHCGR	IMP		Human	PMID:23227193
Biological Process	GO:0046544	development of secondary male sexual characteristics	Lhcgr	IMP	MGI:MGI:2181999	Mouse	PMID:11145748
Biological Process	GO:0008585	female gonad development	Lhcgr	IMP	MGI:MGI:2181999	Mouse	PMID:15951841
Biological Process	GO:0008585	female gonad development	Lhcgr	IMP	MGI:MGI:2181999	Mouse	PMID:11145748
Biological Process	GO:0008585	female gonad development	lhcgr	IGI	ZFIN:ZDB-GENE-020423-5	Zfish	PMID:26452104
Biological Process	GO:0009755	hormone-mediated signaling pathway	Lhcgr	IDA		Rat	PMID:2502842|RGD:1566529
Biological Process	GO:0042700	luteinizing hormone signaling pathway	LHCGR	IMP		Human	PMID:11847099
Biological Process	GO:0042700	luteinizing hormone signaling pathway	Lhcgr	IDA		Rat	PMID:3030841|RGD:2292625
Biological Process	GO:0008584	male gonad development	Lhcgr	IMP	MGI:MGI:2181999	Mouse	PMID:11145748
Biological Process	GO:0008584	male gonad development	lhcgr	IMP	ZFIN:ZDB-GENO-160126-3	Zfish	PMID:25993524
Biological Process	GO:0001541	ovarian follicle development	Lhcgr	IMP	MGI:MGI:2181999	Mouse	PMID:11145748
Biological Process	GO:0030728	ovulation	lhcgr	IMP	ZFIN:ZDB-GENO-160127-2	Zfish	PMID:25238195
Biological Process	GO:0022602	ovulation cycle process	Lhcgr	IMP	MGI:MGI:2181999	Mouse	PMID:11145748
Biological Process	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	Lhcgr	IDA		Mouse	MGI:MGI:5318037|PMID:10493819
Biological Process	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	Lhcgr	IDA		Rat	PMID:3026357|RGD:2292621
Biological Process	GO:0010524	positive regulation of calcium ion transport into cytosol	Lhcgr	IDA		Rat	PMID:8187959|RGD:2292619
Biological Process	GO:0050850	positive regulation of calcium-mediated signaling	Lhcgr	IDA		Rat	PMID:8187959|RGD:2292619
Biological Process	GO:0046886	positive regulation of hormone biosynthetic process	Lhcgr	IDA		Rat	PMID:3026357|RGD:2292621
Biological Process	GO:0032962	positive regulation of inositol trisphosphate biosynthetic process	Lhcgr	IDA		Mouse	MGI:MGI:5318037|PMID:10493819
Biological Process	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	Lhcgr	IDA		Rat	PMID:8187959|RGD:2292619
Biological Process	GO:0006622	protein targeting to lysosome	Lhcgr	IMP		Rat	PMID:10847593|RGD:2292601
Biological Process	GO:0050810	regulation of steroid biosynthetic process	Lhcgr	IEP		Rat	PMID:17241129|RGD:1600071
Biological Process	GO:0090030	regulation of steroid hormone biosynthetic process	Lhcgr	IMP	MGI:MGI:2181999	Mouse	PMID:11145748
Biological Process	GO:0034699	response to luteinizing hormone	Lhcgr	IDA		Rat	PMID:9553128|RGD:12792999
Biological Process	GO:0009410	response to xenobiotic stimulus	Lhcgr	IEP		Rat	PMID:9653071|RGD:1600297
Biological Process	GO:0072520	seminiferous tubule development	Lhcgr	IMP	MGI:MGI:2181999	Mouse	PMID:11145748
Biological Process	GO:0007283	spermatogenesis	Lhcgr	IMP	MGI:MGI:2181999	Mouse	PMID:11145748
Biological Process	GO:0007283	spermatogenesis	lhcgr	IGI	ZFIN:ZDB-GENE-020423-5	Zfish	PMID:26452104
Biological Process	GO:0060065	uterus development	Lhcgr	IMP	MGI:MGI:2181999	Mouse	PMID:11145748

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern