Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LHX5
  • Mouse genes Lhx5
  • Rat genes Lhx5
  • Zfish genes lhx5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lhx5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	LHX5	IPI	UniProtKB:D3DTS7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LHX5	IPI	UniProtKB:G5E9A7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LHX5	IPI	UniProtKB:O00291	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LHX5	IPI	UniProtKB:O75400-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LHX5	IPI	UniProtKB:P06307	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LHX5	IPI	UniProtKB:P06396	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LHX5	IPI	UniProtKB:P13473-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LHX5	IPI	UniProtKB:P22607	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LHX5	IPI	UniProtKB:P22695	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LHX5	IPI	UniProtKB:P23284	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LHX5	IPI	UniProtKB:P37840	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LHX5	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LHX5	IPI	UniProtKB:P55212	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LHX5	IPI	UniProtKB:P61981	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LHX5	IPI	UniProtKB:P62826	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LHX5	IPI	UniProtKB:Q14957	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LHX5	IPI	UniProtKB:Q15047-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LHX5	IPI	UniProtKB:Q5SUL5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LHX5	IPI	UniProtKB:Q7Z412	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LHX5	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LHX5	IPI	UniProtKB:Q86WV8	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LHX5	IPI	UniProtKB:Q8NI60	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LHX5	IPI	UniProtKB:Q8TAP4-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LHX5	IPI	UniProtKB:Q92993	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LHX5	IPI	UniProtKB:Q9UMX0	Human	PMID:32814053
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	LHX5	IDA		Human	PMID:28473536
Biological Process	GO:0021846	cell proliferation in forebrain	Lhx5	IMP	MGI:MGI:2152620	Mouse	PMID:10325223
Biological Process	GO:0007267	cell-cell signaling	Lhx5	IGI	MGI:MGI:99783	Mouse	PMID:17664423
Biological Process	GO:0021702	cerebellar Purkinje cell differentiation	Lhx5	IGI	MGI:MGI:99783	Mouse	PMID:17664423
Biological Process	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation	Lhx5	IGI	MGI:MGI:99783	Mouse	PMID:17664423
Biological Process	GO:0021549	cerebellum development	Lhx5	IGI	MGI:MGI:99783	Mouse	PMID:17664423
Biological Process	GO:0001654	eye development	lhx5	IGI	ZFIN:ZDB-GENO-020715-4	Zfish	PMID:16854974
Biological Process	GO:0030900	forebrain development	lhx5	IDA		Zfish	PMID:16854974
Biological Process	GO:0030900	forebrain development	lhx5	IMP	ZFIN:ZDB-MRPHLNO-061117-1	Zfish	PMID:16854974
Biological Process	GO:0021879	forebrain neuron differentiation	Lhx5	IMP	MGI:MGI:2152620	Mouse	PMID:10325223
Biological Process	GO:0021766	hippocampus development	Lhx5	IMP	MGI:MGI:2152620	Mouse	PMID:10325223
Biological Process	GO:0007405	neuroblast proliferation	Lhx5	IMP	MGI:MGI:2152620	Mouse	PMID:10325223
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Lhx5	IGI	UniProtKB:P63006	Mouse	MGI:MGI:3695495|PMID:17166926
Biological Process	GO:1902692	regulation of neuroblast proliferation	Lhx5	IMP	MGI:MGI:2152620	Mouse	PMID:10325223
Biological Process	GO:0021527	spinal cord association neuron differentiation	Lhx5	IGI	UniProtKB:P63006	Mouse	MGI:MGI:3695495|PMID:17166926

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern