Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LHX6
  • Mouse genes Lhx6
  • Rat genes Lhx6
  • Zfish genes lhx6a,lhx6b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lhx6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	LHX6	IPI	UniProtKB:Q86U70	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LHX6	IPI	UniProtKB:P36508	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LHX6	IPI	UniProtKB:P52744	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LHX6	IPI	UniProtKB:P57682	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LHX6	IPI	UniProtKB:Q01974	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LHX6	IPI	UniProtKB:Q16656-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LHX6	IPI	UniProtKB:Q6QHK4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LHX6	IPI	UniProtKB:Q86U70-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LHX6	IPI	UniProtKB:Q86YD7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LHX6	IPI	UniProtKB:Q99829	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LHX6	IPI	UniProtKB:D3DTS7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LHX6	IPI	UniProtKB:O14832	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LHX6	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LHX6	IPI	UniProtKB:P01023	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LHX6	IPI	UniProtKB:P04792	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LHX6	IPI	UniProtKB:P28799	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LHX6	IPI	UniProtKB:P37840	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LHX6	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LHX6	IPI	UniProtKB:P54252	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LHX6	IPI	UniProtKB:P54253	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LHX6	IPI	UniProtKB:Q9Y3C5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LHX6	IPI	UniProtKB:Q86U70	Human	PMID:35140242
Molecular Function	GO:0005515	protein binding	Lhx6	IPI	UniProtKB:P70662	Mouse	MGI:MGI:3851324|PMID:10393337
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	LHX6	IDA		Human	PMID:28473536
Cellular Component	GO:0005634	nucleus	LHX6	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005634	nucleus	Lhx6	IDA		Mouse	PMID:17376969
Biological Process	GO:0021853	cerebral cortex GABAergic interneuron migration	Lhx6	IMP	MGI:MGI:3702518	Mouse	PMID:17376969
Biological Process	GO:0021895	cerebral cortex neuron differentiation	Lhx6	IGI	MGI:MGI:108067	Mouse	PMID:18339674
Biological Process	GO:0021799	cerebral cortex radially oriented cell migration	Lhx6	IMP	MGI:MGI:3702518	Mouse	PMID:17376969
Biological Process	GO:0021800	cerebral cortex tangential migration	Lhx6	IMP	MGI:MGI:3702518	Mouse	PMID:17376969
Biological Process	GO:0021884	forebrain neuron development	Lhx6	IGI	MGI:MGI:1096343	Mouse	PMID:15217369
Biological Process	GO:0021877	forebrain neuron fate commitment	Lhx6	IGI	MGI:MGI:108067	Mouse	PMID:18339674
Biological Process	GO:0042551	neuron maturation	Lhx6	IMP	MGI:MGI:3702518	Mouse	PMID:17376969
Biological Process	GO:0001764	neuron migration	Lhx6	IMP	MGI:MGI:3702518	Mouse	PMID:17376969

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern