Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LIG1
  • Mouse genes Lig1
  • Rat genes Lig1
  • Zfish genes lig1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lig1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003909	DNA ligase activity	LIG1	IMP		Human	PMID:15871698
Molecular Function	GO:0003909	DNA ligase activity	LIG1	IDA		Human	PMID:9809069
Molecular Function	GO:0003909	DNA ligase activity	Lig1	IDA		Rat	PMID:1730240|RGD:724410
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	LIG1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	LIG1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Lig1	IDA		Mouse	PMID:9001252
Cellular Component	GO:0005634	nucleus	Lig1	IDA		Rat	PMID:15942958|RGD:1598733
Biological Process	GO:0006284	base-excision repair	LIG1	IDA		Human	PMID:19589734
Biological Process	GO:0006281	DNA repair	Lig1	IMP		Mouse	PMID:21390131
Biological Process	GO:0006281	DNA repair	Lig1	IDA		Rat	PMID:1730240|RGD:724410
Biological Process	GO:0006260	DNA replication	Lig1	IMP	MGI:MGI:2179196	Mouse	PMID:11896201
Biological Process	GO:0006303	double-strand break repair via nonhomologous end joining	Lig1	IMP		Mouse	PMID:21655080
Biological Process	GO:0042542	response to hydrogen peroxide	Lig1	IMP		Mouse	PMID:21390131

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern