Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LIG3
  • Mouse genes Lig3
  • Rat genes Lig3
  • Zfish genes lig3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lig3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003909	DNA ligase activity	LIG3	IDA		Human	PMID:9809069
Molecular Function	GO:0003909	DNA ligase activity	Lig3	IDA		Rat	PMID:17412650|RGD:2302580
Molecular Function	GO:0005515	protein binding	LIG3	IPI	UniProtKB:Q9NUW8	Human	PMID:15744309
Molecular Function	GO:0005515	protein binding	LIG3	IPI	UniProtKB:Q9ULZ3	Human	PMID:24407287
Molecular Function	GO:0005515	protein binding	LIG3	IPI	UniProtKB:P61244	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	LIG3	IPI	UniProtKB:P54098	Human	PMID:33855352
Cellular Component	GO:0000794	condensed nuclear chromosome	Lig3	IDA		Mouse	PMID:9001252
Cellular Component	GO:0005739	mitochondrion	Lig3	IMP		Mouse	MGI:MGI:4943978|PMID:21390131
Cellular Component	GO:0005654	nucleoplasm	LIG3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Lig3	IDA		Rat	PMID:17412650|RGD:2302580
Cellular Component	GO:0000795	synaptonemal complex	Lig3	IDA		Mouse	PMID:9001252
Biological Process	GO:0006288	base-excision repair, DNA ligation	LIG3	IDA		Human	PMID:19589734
Biological Process	GO:0006288	base-excision repair, DNA ligation	Lig3	IDA		Rat	PMID:17412650|RGD:2302580
Biological Process	GO:0006302	double-strand break repair	LIG3	IDA		Human	PMID:19589734
Biological Process	GO:0097681	double-strand break repair via alternative nonhomologous end joining	Lig3	IMP		Mouse	MGI:MGI:5014103|PMID:21655080
Biological Process	GO:0097681	double-strand break repair via alternative nonhomologous end joining	lig3	IMP	ZFIN:ZDB-MRPHLNO-160119-1	Zfish	PMID:26318124
Biological Process	GO:0097681	double-strand break repair via alternative nonhomologous end joining	lig3	IMP	ZFIN:ZDB-MRPHLNO-131031-3	Zfish	PMID:26318124
Biological Process	GO:0006303	double-strand break repair via nonhomologous end joining	Lig3	IMP		Mouse	PMID:21655080
Biological Process	GO:0043504	mitochondrial DNA repair	Lig3	IMP		Mouse	PMID:21390131
Biological Process	GO:0043504	mitochondrial DNA repair	Lig3	IMP		Mouse	PMID:21390132
Biological Process	GO:0007005	mitochondrion organization	Lig3	IMP		Mouse	MGI:MGI:4943978|PMID:21390131
Biological Process	GO:0045910	negative regulation of DNA recombination	Lig3	IMP	MGI:MGI:3629052	Mouse	PMID:16648486
Biological Process	GO:0090298	negative regulation of mitochondrial DNA replication	LIG3	IMP		Human	PMID:21878356

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern