Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LIMCH1
  • Mouse genes Limch1
  • Rat genes Limch1
  • Zfish genes limch1a,limch1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Limch1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0032034	myosin II head/neck binding	LIMCH1	IDA		Human	PMID:28228547
Molecular Function	GO:0032034	myosin II head/neck binding	LIMCH1	IPI	UniProtKB:P35579	Human	PMID:28228547
Cellular Component	GO:0001725	stress fiber	LIMCH1	IDA		Human	PMID:28228547
Biological Process	GO:0060327	cytoplasmic actin-based contraction involved in cell motility	LIMCH1	IMP		Human	PMID:28228547
Biological Process	GO:0030336	negative regulation of cell migration	LIMCH1	IMP		Human	PMID:28228547
Biological Process	GO:0001934	positive regulation of protein phosphorylation	LIMCH1	IMP		Human	PMID:28228547
Biological Process	GO:0051496	positive regulation of stress fiber assembly	LIMCH1	IMP		Human	PMID:28228547
Biological Process	GO:0051893	regulation of focal adhesion assembly	LIMCH1	IMP		Human	PMID:28228547

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern