Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LIMD1
  • Mouse genes Limd1
  • Rat genes Limd1
  • Zfish genes limd1a,limd1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Limd1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	LIMD1	IPI	UniProtKB:P06400	Human	PMID:15542589
Molecular Function	GO:0005515	protein binding	LIMD1	IPI	UniProtKB:O95863	Human	PMID:18331720
Molecular Function	GO:0005515	protein binding	LIMD1	IPI	UniProtKB:O95835	Human	PMID:20303269
Molecular Function	GO:0005515	protein binding	LIMD1	IPI	UniProtKB:Q9NRM7	Human	PMID:20303269
Molecular Function	GO:0005515	protein binding	LIMD1	IPI	UniProtKB:P06730	Human	PMID:20616046
Molecular Function	GO:0005515	protein binding	LIMD1	IPI	UniProtKB:P26196	Human	PMID:20616046
Molecular Function	GO:0005515	protein binding	LIMD1	IPI	UniProtKB:Q8IU60	Human	PMID:20616046
Molecular Function	GO:0005515	protein binding	LIMD1	IPI	UniProtKB:Q9UKV8	Human	PMID:20616046
Molecular Function	GO:0005515	protein binding	LIMD1	IPI	UniProtKB:Q9UL18	Human	PMID:20616046
Molecular Function	GO:0005515	protein binding	LIMD1	IPI	UniProtKB:Q9Q2G4	Human	PMID:22190034
Molecular Function	GO:0005515	protein binding	LIMD1	IPI	UniProtKB:P40337	Human	PMID:22286099
Molecular Function	GO:0005515	protein binding	LIMD1	IPI	UniProtKB:Q96KS0	Human	PMID:22286099
Molecular Function	GO:0005515	protein binding	LIMD1	IPI	UniProtKB:Q9GZT9	Human	PMID:22286099
Molecular Function	GO:0005515	protein binding	LIMD1	IPI	UniProtKB:Q9H6Z9	Human	PMID:22286099
Molecular Function	GO:0005515	protein binding	LIMD1	IPI	UniProtKB:Q9UKV8	Human	PMID:28683311
Molecular Function	GO:0005515	protein binding	LIMD1	IPI	UniProtKB:Q9UL18	Human	PMID:28683311
Molecular Function	GO:0005515	protein binding	Limd1	IPI	UniProtKB:P19382|UniProtKB:P97469|UniProtKB:Q02085|UniProtKB:Q99M85	Mouse	MGI:MGI:5318024|PMID:18331720
Molecular Function	GO:0005515	protein binding	Limd1	IPI	UniProtKB:P70196	Mouse	MGI:MGI:3698661|PMID:17092936
Molecular Function	GO:0003714	transcription corepressor activity	Limd1	IDA		Mouse	MGI:MGI:3773767|PMID:17909014
Cellular Component	GO:0005912	adherens junction	LIMD1	IDA		Human	PMID:20303269
Cellular Component	GO:0005737	cytoplasm	LIMD1	IDA		Human	PMID:15542589
Cellular Component	GO:0005737	cytoplasm	LIMD1	IDA		Human	PMID:18439753
Cellular Component	GO:0005737	cytoplasm	Limd1	IDA		Mouse	MGI:MGI:3807091|PMID:18657804
Cellular Component	GO:0005925	focal adhesion	LIMD1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005925	focal adhesion	LIMD1	IDA		Human	PMID:18439753
Cellular Component	GO:0005654	nucleoplasm	LIMD1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	LIMD1	IDA		Human	PMID:15542589
Cellular Component	GO:0005634	nucleus	LIMD1	IDA		Human	PMID:18439753
Cellular Component	GO:0000932	P-body	LIMD1	IDA		Human	PMID:20616046
Cellular Component	GO:0005886	plasma membrane	LIMD1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016442	RISC complex	LIMD1	IDA		Human	PMID:20616046
Biological Process	GO:0016477	cell migration	LIMD1	IMP		Human	PMID:21834987
Biological Process	GO:0007010	cytoskeleton organization	LIMD1	IMP		Human	PMID:21834987
Biological Process	GO:0035195	miRNA-mediated gene silencing	LIMD1	IMP		Human	PMID:20616046
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	Limd1	IMP		Mouse	MGI:MGI:3807091|PMID:18657804
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	LIMD1	IDA		Human	PMID:15542589
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	LIMD1	IMP		Human	PMID:22286099
Biological Process	GO:0035331	negative regulation of hippo signaling	LIMD1	IDA		Human	PMID:20303269
Biological Process	GO:0045668	negative regulation of osteoblast differentiation	Limd1	IMP		Mouse	MGI:MGI:3807091|PMID:18657804
Biological Process	GO:0002076	osteoblast development	Limd1	IMP		Mouse	MGI:MGI:3698661|PMID:17092936
Biological Process	GO:0002076	osteoblast development	Limd1	IMP		Mouse	MGI:MGI:3807091|PMID:18657804
Biological Process	GO:0033962	P-body assembly	LIMD1	IMP		Human	PMID:20616046
Biological Process	GO:0016310	phosphorylation	LIMD1	IDA		Human	PMID:18439753
Biological Process	GO:2000637	positive regulation of miRNA-mediated gene silencing	LIMD1	IMP		Human	PMID:20616046
Biological Process	GO:0008360	regulation of cell shape	LIMD1	IMP		Human	PMID:21834987
Biological Process	GO:0001666	response to hypoxia	LIMD1	IDA		Human	PMID:22286099

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern