Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LINGO1
  • Mouse genes Lingo1
  • Rat genes Lingo1
  • Zfish genes lingo1a,lingo1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lingo1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005154	epidermal growth factor receptor binding	Lingo1	IPI	PR:Q01279	Mouse	PMID:17726113
Molecular Function	GO:0005515	protein binding	LINGO1	IPI	UniProtKB:P08138	Human	PMID:14966521
Molecular Function	GO:0005515	protein binding	LINGO1	IPI	UniProtKB:Q99M75	Human	PMID:14966521
Molecular Function	GO:0005515	protein binding	LINGO1	IPI	UniProtKB:P00533	Human	PMID:17726113
Molecular Function	GO:0005515	protein binding	LINGO1	IPI	UniProtKB:P08138	Human	PMID:20659559
Molecular Function	GO:0005515	protein binding	LINGO1	IPI	UniProtKB:P05067-4	Human	PMID:22133804
Molecular Function	GO:0005515	protein binding	LINGO1	IPI	UniProtKB:P14373	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LINGO1	IPI	UniProtKB:Q08379	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LINGO1	IPI	UniProtKB:Q96R06	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LINGO1	IPI	UniProtKB:O43559	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LINGO1	IPI	UniProtKB:P23142-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LINGO1	IPI	UniProtKB:P26371	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LINGO1	IPI	UniProtKB:Q6L8G9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LINGO1	IPI	UniProtKB:Q8N5G2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LINGO1	IPI	UniProtKB:Q9BYQ4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LINGO1	IPI	UniProtKB:Q9H2F3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LINGO1	IPI	UniProtKB:Q9P121-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LINGO1	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Lingo1	IPI	UniProtKB:P12023	Mouse	MGI:MGI:3829123|PMID:17934213
Molecular Function	GO:0005515	protein binding	Lingo1	IPI	PR:Q01279	Mouse	PMID:15695332
Molecular Function	GO:0005515	protein binding	Lingo1	IPI	PR:Q01279	Mouse	PMID:15728722
Molecular Function	GO:0005515	protein binding	Lingo1	IPI	PR:Q01279	Mouse	PMID:17726113
Molecular Function	GO:0005515	protein binding	lingo1b	IPI	UniProtKB:Q6NW92	Zfish	PMID:20802085|ZFIN:ZDB-PUB-100910-6
Molecular Function	GO:0005515	protein binding	lingo1b	IPI	UniProtKB:A8BB44	Zfish	PMID:19765300
Molecular Function	GO:0005515	protein binding	lingo1a	IPI	UniProtKB:Q66HV9	Zfish	PMID:19765300
Biological Process	GO:0031103	axon regeneration	lingo1a	IMP	ZFIN:ZDB-MRPHLNO-100520-2	Zfish	PMID:19962310
Biological Process	GO:0021954	central nervous system neuron development	Lingo1	IDA		Mouse	PMID:17726113
Biological Process	GO:0021954	central nervous system neuron development	Lingo1	IMP	MGI:MGI:3623893	Mouse	PMID:17726113
Biological Process	GO:0042552	myelination	lingo1b	IMP	ZFIN:ZDB-MRPHLNO-140606-5	Zfish	PMID:24262204
Biological Process	GO:0048715	negative regulation of oligodendrocyte differentiation	Lingo1	IMP		Mouse	PMID:15895088
Biological Process	GO:0048666	neuron development	lingo1b	IMP	ZFIN:ZDB-MRPHLNO-140606-5	Zfish	PMID:24262204
Biological Process	GO:0031175	neuron projection development	Lingo1	IDA		Mouse	PMID:17726113
Biological Process	GO:0048709	oligodendrocyte differentiation	Lingo1	IMP		Mouse	PMID:15895088
Biological Process	GO:0043491	protein kinase B signaling	Lingo1	IDA		Mouse	PMID:17726113

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern