Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Lipe

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes LIPE
- Mouse genes Lipe
- Rat genes Lipe
- Zfish genes lipea,lipeb
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lipe

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0102259	1,2-diacylglycerol acylhydrolase activity	Lipe	IDA		Mouse	MGI:MGI:5465510\|PMID:23066022
Molecular Function	GO:0102258	1,3-diacylglycerol acylhydrolase activity	Lipe	IDA		Mouse	MGI:MGI:5465510\|PMID:23066022
Molecular Function	GO:0047372	acylglycerol lipase activity	Lipe	IDA		Mouse	MGI:MGI:5008527\|PMID:21454566
Molecular Function	GO:0047372	acylglycerol lipase activity	Lipe	IDA		Rat	PMID:15627655\|RGD:1581872
Molecular Function	GO:0033878	hormone-sensitive lipase activity	LIPE	IDA		Human	PMID:19800417
Molecular Function	GO:0033878	hormone-sensitive lipase activity	LIPE	IDA		Human	PMID:8812477
Molecular Function	GO:0033878	hormone-sensitive lipase activity	Lipe	IDA		Rat	PMID:6643478\|RGD:30309921
Molecular Function	GO:0016788	hydrolase activity, acting on ester bonds	Lipe	IDA		Rat	PMID:15697220\|RGD:1581871
Molecular Function	GO:0005515	protein binding	LIPE	IPI	UniProtKB:Q6NZI2	Human	PMID:17026959
Molecular Function	GO:0005515	protein binding	LIPE	IPI	UniProtKB:Q3SY00	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Lipe	IPI	UniProtKB:Q8BVZ1	Mouse	MGI:MGI:5559670\|PMID:19717842
Molecular Function	GO:0005515	protein binding	Lipe	IPI	RGD:69309	Rat	PMID:10318917\|RGD:68775
Molecular Function	GO:0005515	protein binding	Lipe	IPI	RGD:3770	Rat	PMID:12925534\|RGD:1600085
Molecular Function	GO:0005515	protein binding	Lipe	IPI	UniProtKB:M0R7Z9	Rat	PMID:24303154\|RGD:8553664
Molecular Function	GO:0019901	protein kinase binding	Lipe	IPI	UniProtKB:Q5EG47	Mouse	MGI:MGI:5284794\|PMID:15878856
Molecular Function	GO:0050253	retinyl-palmitate esterase activity	LIPE	IDA		Human	PMID:15955102
Molecular Function	GO:0050253	retinyl-palmitate esterase activity	Lipe	IDA		Mouse	MGI:MGI:6437029\|PMID:15550674
Molecular Function	GO:0050253	retinyl-palmitate esterase activity	Lipe	IDA		Rat	PMID:9162045\|RGD:30309933
Molecular Function	GO:0017171	serine hydrolase activity	Lipe	IDA		Mouse	PMID:16818490
Molecular Function	GO:0004771	sterol esterase activity	LIPE	IDA		Human	PMID:15716583
Molecular Function	GO:0004771	sterol esterase activity	LIPE	IDA		Human	PMID:8812477
Molecular Function	GO:0004771	sterol esterase activity	Lipe	IDA		Mouse	MGI:MGI:6437029\|PMID:15550674
Molecular Function	GO:0004771	sterol esterase activity	Lipe	IDA		Mouse	MGI:MGI:4837316\|PMID:20625037
Molecular Function	GO:0004771	sterol esterase activity	Lipe	IDA		Rat	PMID:10694408\|RGD:30309930
Molecular Function	GO:0004771	sterol esterase activity	Lipe	IDA		Rat	PMID:9162045\|RGD:30309933
Molecular Function	GO:0004806	triglyceride lipase activity	LIPE	IDA		Human	PMID:15716583
Molecular Function	GO:0004806	triglyceride lipase activity	LIPE	IDA		Human	PMID:15955102
Molecular Function	GO:0004806	triglyceride lipase activity	Lipe	IDA		Mouse	MGI:MGI:4837316\|PMID:20625037
Molecular Function	GO:0004806	triglyceride lipase activity	Lipe	IDA		Mouse	MGI:MGI:6437029\|PMID:15550674
Molecular Function	GO:0004806	triglyceride lipase activity	Lipe	IMP	MGI:MGI:2388334	Mouse	PMID:17074755
Molecular Function	GO:0004806	triglyceride lipase activity	Lipe	IDA		Rat	PMID:9162045\|RGD:30309933
Cellular Component	GO:0005737	cytoplasm	Lipe	IDA		Rat	PMID:15654127\|RGD:1625027
Cellular Component	GO:0005829	cytosol	LIPE	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Lipe	IDA		Mouse	MGI:MGI:6437029\|PMID:15550674
Cellular Component	GO:0005829	cytosol	Lipe	IDA		Mouse	PMID:17074755
Cellular Component	GO:0005829	cytosol	Lipe	IDA		Mouse	PMID:16804080
Cellular Component	GO:0005615	extracellular space	Lipe	IDA		Rat	PMID:15654127\|RGD:1625027
Cellular Component	GO:0005811	lipid droplet	Lipe	IDA		Mouse	MGI:MGI:5284794\|PMID:15878856
Cellular Component	GO:0005811	lipid droplet	Lipe	IDA		Mouse	PMID:30862682
Cellular Component	GO:0005811	lipid droplet	Lipe	IDA		Mouse	PMID:16804080
Cellular Component	GO:0016020	membrane	Lipe	IDA		Mouse	MGI:MGI:6437029\|PMID:15550674
Biological Process	GO:0070417	cellular response to cold	Lipe	IDA		Mouse	PMID:30862682
Biological Process	GO:0046340	diacylglycerol catabolic process	Lipe	IDA		Mouse	MGI:MGI:5465510\|PMID:23066022
Biological Process	GO:0046340	diacylglycerol catabolic process	Lipe	IDA		Mouse	PMID:16804080
Biological Process	GO:0046340	diacylglycerol catabolic process	Lipe	IMP	MGI:MGI:2388334	Mouse	PMID:11717312
Biological Process	GO:0046485	ether lipid metabolic process	Lipe	IDA		Mouse	MGI:MGI:4837316\|PMID:20625037
Biological Process	GO:0007565	female pregnancy	Lipe	IEP		Rat	PMID:16328496\|RGD:1581870
Biological Process	GO:0016042	lipid catabolic process	Lipe	IDA		Mouse	MGI:MGI:5284794\|PMID:15878856
Biological Process	GO:0042758	long-chain fatty acid catabolic process	Lipe	IDA		Mouse	PMID:16804080
Biological Process	GO:0009410	response to xenobiotic stimulus	Lipe	IEP		Rat	PMID:11016888\|RGD:2313581
Biological Process	GO:0009410	response to xenobiotic stimulus	Lipe	IEP		Rat	PMID:16906479\|RGD:1581869
Biological Process	GO:0019433	triglyceride catabolic process	Lipe	IDA		Mouse	PMID:16804080
Biological Process	GO:0019433	triglyceride catabolic process	Lipe	IMP	MGI:MGI:2388334	Mouse	PMID:11717312
Biological Process	GO:0019433	triglyceride catabolic process	Lipe	IMP	MGI:MGI:2388334	Mouse	PMID:17074755
Biological Process	GO:0019433	triglyceride catabolic process	Lipe	IDA		Rat	PMID:14739077\|RGD:1581873

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.