Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LITAF
  • Mouse genes Litaf
  • Rat genes Litaf
  • Zfish genes litaf
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Litaf

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	LITAF	IMP		Human	PMID:21217782
Molecular Function	GO:0042802	identical protein binding	LITAF	IPI	UniProtKB:Q99732	Human	PMID:27927196
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q9NZC7	Human	PMID:15064722
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:P46934	Human	PMID:16118794
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q99816	Human	PMID:16118794
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:O14964	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:O75886	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:O95817	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q13137	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q96HR9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q9UMX0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q9UMX0-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:O14964	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:O75886	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q13137	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q96CV9-2	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q96HR9	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q9UMX0-2	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:P46934	Human	PMID:27927196
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q86WH2	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q9UM19	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:O14964	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:O75886	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:O95817	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q96HR9	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:I6L9I8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:O00291	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:O60784-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:O75113	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:O75886	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:O95208-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:O95231	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:O95817	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:P37235	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:P61601	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:P62760	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:P62979	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:P62987	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q02930-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q03989	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q15025	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q15038	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q15915	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q6PIL6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q7Z3K3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q86VP1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q86WH2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q96HR9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q96KP6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q9H0X6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q9NZ52-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q9NZC7-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q9NZI2-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q9UHD9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q9UM19	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q9Y6I3-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:O00291	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:O00308	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:O14933	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:O15195-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:P13473-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:P80723	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:P83916	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q8N6K7-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q8N8N0	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q8NI60	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q8TCE9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q92608-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q92828	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q96CV9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q96D59	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q96HP8	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q96T52-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q99717	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q9BVU5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q9BXL8	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q9BYD3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q9C0H9-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q9HC96	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q9NR30	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q9NS23-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q9UKA4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:Q9UN19	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:P46934	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	LITAF	IPI	UniProtKB:P46937	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	Litaf	IPI	PR:P46935	Mouse	PMID:11042109
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	LITAF	IDA		Human	PMID:12655064
Molecular Function	GO:0050699	WW domain binding	LITAF	IPI	UniProtKB:Q9NZC7	Human	PMID:15064722
Molecular Function	GO:0008270	zinc ion binding	LITAF	IDA		Human	PMID:27582497
Cellular Component	GO:0098559	cytoplasmic side of early endosome membrane	LITAF	IDA		Human	PMID:27582497
Cellular Component	GO:0098560	cytoplasmic side of late endosome membrane	LITAF	IDA		Human	PMID:27582497
Cellular Component	GO:0098574	cytoplasmic side of lysosomal membrane	LITAF	IDA		Human	PMID:27582497
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	LITAF	IDA		Human	PMID:27582497
Cellular Component	GO:0005794	Golgi apparatus	LITAF	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	LITAF	IDA		Human	PMID:15064722
Cellular Component	GO:0005794	Golgi apparatus	LITAF	IMP		Human	PMID:16118794
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	LITAF	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005765	lysosomal membrane	LITAF	IDA		Human	PMID:11274176
Cellular Component	GO:0005654	nucleoplasm	LITAF	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	LITAF	IMP		Human	PMID:16118794
Biological Process	GO:0007568	aging	Litaf	IEP		Rat	PMID:21633715|RGD:7247626
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Litaf	IMP	MGI:MGI:3687962	Mouse	PMID:16954198
Biological Process	GO:1901223	negative regulation of NIK/NF-kappaB signaling	Litaf	IMP		Mouse	PMID:12914755
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	LITAF	HMP		Human	PMID:12761501
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	LITAF	IMP		Human	PMID:21217782
Biological Process	GO:0010935	regulation of macrophage cytokine production	Litaf	IMP	MGI:MGI:3687962	Mouse	PMID:16954198
Biological Process	GO:0032496	response to lipopolysaccharide	Litaf	IMP	MGI:MGI:2182767,MGI:MGI:3687962	Mouse	PMID:22160695

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern