Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LPAR6
  • Mouse genes Lpar6
  • Rat genes Lpar6
  • Zfish genes lpar6a,lpar6b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lpar6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070915	lysophosphatidic acid receptor activity	lpar6a	IDA		Zfish	PMID:21971049
Molecular Function	GO:0070915	lysophosphatidic acid receptor activity	lpar6a	IDA		Zfish	PMID:28792932
Molecular Function	GO:0070915	lysophosphatidic acid receptor activity	lpar6b	IDA		Zfish	PMID:21971049
Molecular Function	GO:0005515	protein binding	LPAR6	IPI	UniProtKB:P54849	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LPAR6	IPI	UniProtKB:Q96IW7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LPAR6	IPI	UniProtKB:Q9BZL3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LPAR6	IPI	UniProtKB:Q9NS64	Human	PMID:32296183
Cellular Component	GO:0005886	plasma membrane	LPAR6	IDA		Human	PMID:18297070
Biological Process	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	lpar6a	IMP		Zfish	PMID:28792932|ZFIN:ZDB-PUB-180123-14
Biological Process	GO:0001525	angiogenesis	lpar6a	IGI	ZFIN:ZDB-MRPHLNO-120123-10,ZFIN:ZDB-MRPHLNO-120123-9,ZFIN:ZDB-MRPHLNO-120202-2	Zfish	PMID:21971049
Biological Process	GO:0001525	angiogenesis	lpar6a	IGI	ZFIN:ZDB-MRPHLNO-120123-10,ZFIN:ZDB-MRPHLNO-120123-9	Zfish	PMID:21971049
Biological Process	GO:0001525	angiogenesis	lpar6a	IMP	ZFIN:ZDB-MRPHLNO-091217-1	Zfish	PMID:19389629
Biological Process	GO:0001525	angiogenesis	lpar6a	IMP	ZFIN:ZDB-MRPHLNO-091217-1,ZFIN:ZDB-MRPHLNO-091217-2	Zfish	PMID:19389629
Biological Process	GO:0001525	angiogenesis	lpar6a	IMP	ZFIN:ZDB-MRPHLNO-091217-2	Zfish	PMID:19389629
Biological Process	GO:0001525	angiogenesis	lpar6b	IGI	ZFIN:ZDB-MRPHLNO-120123-10,ZFIN:ZDB-MRPHLNO-120123-9	Zfish	PMID:21971049
Biological Process	GO:0001525	angiogenesis	lpar6b	IGI	ZFIN:ZDB-MRPHLNO-120123-10,ZFIN:ZDB-MRPHLNO-120123-9,ZFIN:ZDB-MRPHLNO-120202-2	Zfish	PMID:21971049
Biological Process	GO:0001835	blastocyst hatching	Lpar6	IMP		Mouse	PMID:27869233
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	lpar6a	IDA		Zfish	PMID:28792932|ZFIN:ZDB-PUB-180123-14

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern