Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Lpin1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes LPIN1
- Mouse genes Lpin1
- Rat genes Lpin1
- Zfish genes lpin1a,lpin1b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lpin1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042826	histone deacetylase binding	Lpin1	IDA		Mouse	PMID:20385772
Molecular Function	GO:0042975	peroxisome proliferator activated receptor binding	Lpin1	IPI	UniProtKB:P23204	Mouse	MGI:MGI:3770090\|PMID:16950137
Molecular Function	GO:0008195	phosphatidate phosphatase activity	LPIN1	EXP		Human	PMID:18694939
Molecular Function	GO:0008195	phosphatidate phosphatase activity	LPIN1	IDA		Human	PMID:29765047
Molecular Function	GO:0008195	phosphatidate phosphatase activity	Lpin1	IDA		Mouse	MGI:MGI:4943609\|PMID:21397848
Molecular Function	GO:0008195	phosphatidate phosphatase activity	Lpin1	IDA		Mouse	PMID:17158099
Molecular Function	GO:0005515	protein binding	LPIN1	IPI	UniProtKB:O60333-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LPIN1	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LPIN1	IPI	UniProtKB:P01100	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LPIN1	IPI	UniProtKB:P04792	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LPIN1	IPI	UniProtKB:P09172	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LPIN1	IPI	UniProtKB:P12931	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LPIN1	IPI	UniProtKB:P14136	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LPIN1	IPI	UniProtKB:P21333-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LPIN1	IPI	UniProtKB:P28799	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LPIN1	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LPIN1	IPI	UniProtKB:P50440	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LPIN1	IPI	UniProtKB:P62993	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LPIN1	IPI	UniProtKB:Q00403	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LPIN1	IPI	UniProtKB:Q00613	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LPIN1	IPI	UniProtKB:Q01658	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LPIN1	IPI	UniProtKB:Q8N2W9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LPIN1	IPI	UniProtKB:Q8WXH2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LPIN1	IPI	UniProtKB:Q9UBB4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LPIN1	IPI	UniProtKB:Q9Y3C5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LPIN1	IPI	UniProtKB:Q9Y5Q9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Lpin1	IPI	UniProtKB:Q8CFN5	Mouse	MGI:MGI:4441113\|PMID:19753306
Molecular Function	GO:0005515	protein binding	Lpin1	IPI	UniProtKB:O70343	Mouse	MGI:MGI:3770090\|PMID:16950137
Molecular Function	GO:0005515	protein binding	Lpin1	IPI	PR:Q8K120	Mouse	PMID:20385772
Molecular Function	GO:0005515	protein binding	Lpin1	IPI	PR:P23204	Mouse	PMID:20385772
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	Lpin1	IDA		Mouse	PMID:20385772
Molecular Function	GO:0003713	transcription coactivator activity	Lpin1	IDA		Mouse	MGI:MGI:3770090\|PMID:16950137
Molecular Function	GO:0003713	transcription coactivator activity	Lpin1	IDA		Mouse	MGI:MGI:4441113\|PMID:19753306
Cellular Component	GO:0005737	cytoplasm	Lpin1	IDA		Mouse	MGI:MGI:4441113\|PMID:19753306
Cellular Component	GO:0005737	cytoplasm	Lpin1	IDA		Mouse	MGI:MGI:5307934\|PMID:22134922
Cellular Component	GO:0005737	cytoplasm	Lpin1	IDA		Mouse	MGI:MGI:4943609\|PMID:21397848
Cellular Component	GO:0005737	cytoplasm	Lpin1	IDA		Mouse	MGI:MGI:6377845\|PMID:26475860
Cellular Component	GO:0005829	cytosol	LPIN1	IDA		Human	PMID:29765047
Cellular Component	GO:0005783	endoplasmic reticulum	LPIN1	IDA		Human	PMID:29765047
Cellular Component	GO:0005783	endoplasmic reticulum	Lpin1	IDA		Mouse	MGI:MGI:6377845\|PMID:26475860
Cellular Component	GO:0005741	mitochondrial outer membrane	Lpin1	IDA		Mouse	MGI:MGI:4943609\|PMID:21397848
Cellular Component	GO:0031965	nuclear membrane	Lpin1	IDA		Mouse	MGI:MGI:5307934\|PMID:22134922
Cellular Component	GO:0005634	nucleus	Lpin1	IDA		Mouse	MGI:MGI:6377845\|PMID:26475860
Cellular Component	GO:0005634	nucleus	Lpin1	IDA		Mouse	MGI:MGI:4441113\|PMID:19753306
Cellular Component	GO:0005634	nucleus	Lpin1	IDA		Mouse	PMID:11138012
Cellular Component	GO:0005634	nucleus	Lpin1	IDA		Mouse	PMID:20385772
Cellular Component	GO:0005667	transcription regulator complex	Lpin1	IDA		Mouse	PMID:20385772
Biological Process	GO:0030036	actin cytoskeleton organization	Lpin1	IMP	MGI:MGI:1856603	Mouse	PMID:10438476
Biological Process	GO:0031100	animal organ regeneration	Lpin1	IEP		Rat	PMID:14718385\|RGD:1641826
Biological Process	GO:0044255	cellular lipid metabolic process	Lpin1	IMP	MGI:MGI:3799353	Mouse	PMID:22337502
Biological Process	GO:0032869	cellular response to insulin stimulus	Lpin1	IMP	MGI:MGI:1856603	Mouse	PMID:10438476
Biological Process	GO:0032869	cellular response to insulin stimulus	Lpin1	IDA		Rat	PMID:11792863\|RGD:1641823
Biological Process	GO:0009062	fatty acid catabolic process	Lpin1	IDA		Mouse	MGI:MGI:3770090\|PMID:16950137
Biological Process	GO:0006955	immune response	Lpin1	IMP	MGI:MGI:3799353	Mouse	PMID:22337502
Biological Process	GO:0006629	lipid metabolic process	Lpin1	IMP	MGI:MGI:1856603	Mouse	PMID:2722772
Biological Process	GO:0006629	lipid metabolic process	Lpin1	IMP	MGI:MGI:1856603	Mouse	PMID:14522948
Biological Process	GO:0000266	mitochondrial fission	Lpin1	IDA		Mouse	MGI:MGI:4943609\|PMID:21397848
Biological Process	GO:0031642	negative regulation of myelination	Lpin1	IMP		Rat	PMID:21715287\|RGD:38599010
Biological Process	GO:1903741	negative regulation of phosphatidate phosphatase activity	Lpin1	IMP		Rat	PMID:21715287\|RGD:38599010
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Lpin1	IGI	MGI:MGI:1920431	Mouse	PMID:20385772
Biological Process	GO:0006654	phosphatidic acid biosynthetic process	Lpin1	IEP		Rat	PMID:21715287\|RGD:38599010
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	Lpin1	IMP		Mouse	MGI:MGI:5466423\|PMID:23028044
Biological Process	GO:0045740	positive regulation of DNA replication	Lpin1	IMP		Rat	PMID:21715287\|RGD:38599010
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Lpin1	IDA		Mouse	MGI:MGI:3770090\|PMID:16950137
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Lpin1	IGI	MGI:MGI:104740	Mouse	PMID:20385772
Biological Process	GO:0045598	regulation of fat cell differentiation	Lpin1	IMP	MGI:MGI:1856603	Mouse	PMID:11138012
Biological Process	GO:0045598	regulation of fat cell differentiation	Lpin1	IMP	MGI:MGI:1857584	Mouse	PMID:11138012
Biological Process	GO:0031529	ruffle organization	Lpin1	IMP	MGI:MGI:1856603	Mouse	PMID:10438476
Biological Process	GO:0019432	triglyceride biosynthetic process	LPIN1	IDA		Human	PMID:29765047
Biological Process	GO:0006642	triglyceride mobilization	Lpin1	IDA		Mouse	MGI:MGI:3770090\|PMID:16950137

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.