Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LRAT
  • Mouse genes Lrat
  • Rat genes Lrat
  • Zfish genes lrata,lratb.1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lrat

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008374	O-acyltransferase activity	Lrat	IDA		Mouse	PMID:11108736
Molecular Function	GO:0047173	phosphatidylcholine-retinol O-acyltransferase activity	LRAT	IDA		Human	PMID:10819989
Molecular Function	GO:0047173	phosphatidylcholine-retinol O-acyltransferase activity	Lrat	IMP		Mouse	MGI:MGI:6414681|PMID:28758396
Molecular Function	GO:0047173	phosphatidylcholine-retinol O-acyltransferase activity	Lrat	IDA		Rat	PMID:14642897|RGD:6484737
Molecular Function	GO:0047173	phosphatidylcholine-retinol O-acyltransferase activity	Lrat	IDA		Rat	PMID:2253789|RGD:1599829
Molecular Function	GO:0047173	phosphatidylcholine-retinol O-acyltransferase activity	Lrat	IDA		Rat	PMID:8460936|RGD:1599831
Molecular Function	GO:0047173	phosphatidylcholine-retinol O-acyltransferase activity	Lrat	IDA		Rat	PMID:9244401|RGD:1599832
Molecular Function	GO:0047173	phosphatidylcholine-retinol O-acyltransferase activity	lratb.1	IMP	ZFIN:ZDB-MRPHLNO-070313-1	Zfish	PMID:17098734
Molecular Function	GO:0047173	phosphatidylcholine-retinol O-acyltransferase activity	lratb.1	IGI	ZFIN:ZDB-MRPHLNO-050316-2,ZFIN:ZDB-MRPHLNO-070313-1	Zfish	PMID:17098734
Molecular Function	GO:0005515	protein binding	LRAT	IPI	UniProtKB:P62952	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LRAT	IPI	UniProtKB:Q7Z5P4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LRAT	IPI	UniProtKB:Q9Y320	Human	PMID:32296183
Molecular Function	GO:0001972	retinoic acid binding	Lrat	IDA		Rat	PMID:8460936|RGD:1599831
Molecular Function	GO:0001972	retinoic acid binding	Lrat	IDA		Rat	PMID:9244401|RGD:1599832
Molecular Function	GO:0019841	retinol binding	Lrat	IDA		Rat	PMID:2253789|RGD:1599829
Molecular Function	GO:0019841	retinol binding	Lrat	IDA		Rat	PMID:8460936|RGD:1599831
Molecular Function	GO:0019841	retinol binding	Lrat	IDA		Rat	PMID:9244401|RGD:1599832
Cellular Component	GO:0005783	endoplasmic reticulum	Lrat	IDA		Mouse	MGI:MGI:6414681|PMID:28758396
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Lrat	IDA		Rat	PMID:2253789|RGD:1599829
Cellular Component	GO:0005771	multivesicular body	Lrat	IDA		Rat	PMID:18544127|RGD:6893660
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Lrat	IDA		Rat	PMID:18544127|RGD:6893660
Cellular Component	GO:0005791	rough endoplasmic reticulum	Lrat	IDA		Rat	PMID:18544127|RGD:6893660
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	Lrat	IEP		Mouse	PMID:20439489
Biological Process	GO:0009790	embryo development	Lrat	IGI	MGI:MGI:97879	Mouse	PMID:18093970
Biological Process	GO:0032370	positive regulation of lipid transport	Lrat	IGI	MGI:MGI:107742	Mouse	PMID:23105095
Biological Process	GO:0032370	positive regulation of lipid transport	Lrat	IGI	MGI:MGI:1921402	Mouse	PMID:23105095
Biological Process	GO:0009617	response to bacterium	Lrat	IEP		Mouse	PMID:23012479
Biological Process	GO:0032526	response to retinoic acid	Lrat	IEP		Rat	PMID:19700416|RGD:6484694
Biological Process	GO:0033189	response to vitamin A	Lrat	IEP		Rat	PMID:19700416|RGD:6484694
Biological Process	GO:0042572	retinol metabolic process	LRAT	IDA		Human	PMID:10819989
Biological Process	GO:0042572	retinol metabolic process	Lrat	IMP		Mouse	MGI:MGI:6414681|PMID:28758396
Biological Process	GO:0042572	retinol metabolic process	Lrat	IMP	MGI:MGI:3038935	Mouse	PMID:18093970
Biological Process	GO:0042572	retinol metabolic process	Lrat	IGI	MGI:MGI:97879	Mouse	PMID:18093970
Biological Process	GO:0042572	retinol metabolic process	Lrat	IDA		Rat	PMID:14642897|RGD:6484737
Biological Process	GO:0042572	retinol metabolic process	Lrat	IDA		Rat	PMID:2253789|RGD:1599829
Biological Process	GO:0042572	retinol metabolic process	Lrat	IDA		Rat	PMID:8460936|RGD:1599831
Biological Process	GO:0042572	retinol metabolic process	Lrat	IDA		Rat	PMID:9244401|RGD:1599832
Biological Process	GO:0042572	retinol metabolic process	lratb.1	IGI	ZFIN:ZDB-MRPHLNO-050316-3,ZFIN:ZDB-MRPHLNO-070313-1	Zfish	PMID:17098734
Biological Process	GO:0042572	retinol metabolic process	lratb.1	IMP	ZFIN:ZDB-MRPHLNO-070313-1	Zfish	PMID:17098734
Biological Process	GO:0006776	vitamin A metabolic process	Lrat	IMP		Mouse	MGI:MGI:6414681|PMID:28758396
Biological Process	GO:0006776	vitamin A metabolic process	Lrat	IDA		Mouse	PMID:11108736
Biological Process	GO:0006776	vitamin A metabolic process	Lrat	IDA		Rat	PMID:2253789|RGD:1599829
Biological Process	GO:0006776	vitamin A metabolic process	Lrat	IDA		Rat	PMID:8460936|RGD:1599831
Biological Process	GO:0006776	vitamin A metabolic process	Lrat	IDA		Rat	PMID:9244401|RGD:1599832

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern