Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LRRC19
  • Mouse genes Lrrc19
  • Rat genes Lrrc19
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lrrc19

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0038023	signaling receptor activity	Lrrc19	IDA		Mouse	PMID:19679103
Cellular Component	GO:0005886	plasma membrane	Lrrc19	IDA		Mouse	PMID:19679103
Biological Process	GO:0048874	host-mediated regulation of intestinal microbiota composition	Lrrc19	IMP		Mouse	MGI:MGI:6204559|PMID:26776522
Biological Process	GO:0032637	interleukin-8 production	Lrrc19	IDA		Mouse	PMID:19679103
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	LRRC19	IDA		Human	PMID:19679103
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	Lrrc19	IDA		Mouse	PMID:19679103
Biological Process	GO:0001817	regulation of cytokine production	Lrrc19	IMP		Mouse	MGI:MGI:6204559|PMID:26776522
Biological Process	GO:0050727	regulation of inflammatory response	Lrrc19	IMP		Mouse	MGI:MGI:6204559|PMID:26776522
Biological Process	GO:0002224	toll-like receptor signaling pathway	Lrrc19	IDA		Mouse	PMID:19679103
Biological Process	GO:0038008	TRAF-mediated signal transduction	Lrrc19	IMP		Mouse	MGI:MGI:6204559|PMID:26776522

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern