Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LRRC26
  • Mouse genes Lrrc26
  • Rat genes Lrrc26
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lrrc26

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0099104	potassium channel activator activity	LRRC26	IDA		Human	PMID:22547800
Molecular Function	GO:0015459	potassium channel regulator activity	LRRC26	IDA		Human	PMID:20613726
Molecular Function	GO:0005515	protein binding	LRRC26	IPI	UniProtKB:Q12791	Human	PMID:20613726
Molecular Function	GO:0005515	protein binding	LRRC26	IPI	UniProtKB:Q12791-5	Human	PMID:20613726
Molecular Function	GO:0044325	transmembrane transporter binding	LRRC26	IPI	UniProtKB:Q12791	Human	PMID:22547800
Molecular Function	GO:0005249	voltage-gated potassium channel activity	LRRC26	IDA		Human	PMID:22547800
Cellular Component	GO:0070062	extracellular exosome	LRRC26	HDA		Human	PMID:19199708
Cellular Component	GO:0005886	plasma membrane	LRRC26	IDA		Human	PMID:22547800
Cellular Component	GO:0008076	voltage-gated potassium channel complex	LRRC26	IDA		Human	PMID:20613726
Cellular Component	GO:0008076	voltage-gated potassium channel complex	LRRC26	IDA		Human	PMID:22547800
Biological Process	GO:1903818	positive regulation of voltage-gated potassium channel activity	LRRC26	IDA		Human	PMID:22547800
Biological Process	GO:0071805	potassium ion transmembrane transport	LRRC26	IDA		Human	PMID:22547800

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern